1d nanomaterials as building blocks of nanoelectronics

Hydrogen sulfide and neurogenic inflammation in a murine model of polymicrobial sepsis

Hydrogen sulfide and neurogenic inflammation in a murine model of polymicrobial sepsis

... expression and activity of CSE as well as the plasma level of H2S were markedly suppressed Exogenous supply of H2S restored pulmonary expression and activity of CSE, increased plasma H2S level, lowered ... 4.2.4 Reverse transcriptase-polymerase chain reaction analysis 101 4.2.5 Measurement of pulmonary edema 102 4.2.6 Alanine aminotransferase and aspartate aminotransferase assay 102 4.2.7 Statistics ... odor of rotten eggs, has been recognized as an important endogenous gaseous signaling molecule of the cardiovascular, gastrointestinal, genitourinary, and nervous systems Besides acting as a...

Ngày tải lên: 10/09/2015, 08:32

243 448 0
Tài liệu Báo cáo khoa học: The crystal structure of coenzyme B12-dependent glycerol dehydratase in complex with cobalamin and propane-1,2-diol pptx

Tài liệu Báo cáo khoa học: The crystal structure of coenzyme B12-dependent glycerol dehydratase in complex with cobalamin and propane-1,2-diol pptx

... similar to that of diol dehydratase [9] Crystallographic indication of the base-on mode of cobalamin binding in class II ribonucleotide reductase of Lactobacillus leichmannii has also been reported ... dehydratase is defined as the amount of enzyme activity that catalyzes the formation of lmol of propionaldehyde per minute under the assay conditions Protein concentration of crude enzyme was determined ... chromatography As a result, the enzyme was purified 5.0-fold in a yield of 18% This method was employed for crystallization of glycerol dehydratase Kinetic parameters and stereospecificity of recombinant...

Ngày tải lên: 21/02/2014, 03:20

11 602 0
Báo cáo y học: "Rituximab therapy reduces activated B cells in both the peripheral blood and bone marrow of patients with rheumatoid arthritis: depletion of memory B cells correlates with clinical response" potx

Báo cáo y học: "Rituximab therapy reduces activated B cells in both the peripheral blood and bone marrow of patients with rheumatoid arthritis: depletion of memory B cells correlates with clinical response" potx

... The DAS28 was applied to assess clinical efficacy [10] The European League Against Rheumatism response criteria based on DAS28 were used to assess the response to therapy [11] Isolation of mononuclear ... The present project has been funded in part by the Hellenic Society of Rheumatology MN and GB are graduate students of the Graduate Program of the Molecular Basis of Human Diseases References Martinez-Gamboa ... 4:61-69 Papadaki HA, Kritikos HD, Valatas V, Boumpas DT, Eliopoulos GD: Anemia of chronic disease in rheumatoid arthritis is associated with increased apoptosis of bone marrow erythroid cells: improvement...

Ngày tải lên: 09/08/2014, 14:22

8 376 0
Báo cáo y học: "IL-2 production correlates with effector cell differentiation in HIV-specific CD8+ T cells" doc

Báo cáo y học: "IL-2 production correlates with effector cell differentiation in HIV-specific CD8+ T cells" doc

... HIV-positive subjects) of the absolute number of cells for each of the 32 phenotypes, as listed at the bottom of the figure Black bars represent the background, as mean of the absolute number of cytokinepositive ... IL-2, as well as for CD27, CD28, and CD45RA Results for each possible phenotype of cytokine-positive cells were expressed both as a percentage of CD4+ or CD8+ T cells and as an absolute number of ... involvement of IL-2 production in the differentiation of CD8+ effector T cells This has implications for immunotherapy and immunomonitoring of HIV disease, as it suggests that the preservation of HIV-specific...

Ngày tải lên: 10/08/2014, 05:20

14 273 0
báo cáo khoa học: " Expressions of COX-2 and VEGF-C in gastric cancer: correlations with lymphangiogenesis and prognostic implications" ppsx

báo cáo khoa học: " Expressions of COX-2 and VEGF-C in gastric cancer: correlations with lymphangiogenesis and prognostic implications" ppsx

... peritumoral LVD was significantly correlated with lymph node metastasis and invasion depth It was higher in the lymph node metastasis group (10.37 ± 4.61) than in the no lymph node metastasis group ... staining of Cox-2 in the gastric carcinoma: the positive expression of COX-2 protein was stained as yellow or brownish yellow in the cytoplasm of carcinoma cells (LsAB, ×400) The correlation of COX-2, ... period of 60 months, 32 of the 56 assessable cases had died The 5-year overall survival (OS) for all patients was 42.9% Analysis of the impact of COX-2 status is shown in Figure Six cases had...

Ngày tải lên: 10/08/2014, 10:21

8 519 0
báo cáo khoa học: "EGFR and COX-2 protein expression in non-small cell lung cancer and the correlation with clinical features" pptx

báo cáo khoa học: "EGFR and COX-2 protein expression in non-small cell lung cancer and the correlation with clinical features" pptx

... the predominant patterns of COX-2 and EGFR staining were cytoplasmic However, in our study, the positivity of COX-2 in tumor was as high as 90%, and the number of cases was too small to analyze ... TNM stages (P > 0.05) However, EGFR over-expression was correlated with lymph node metastasis, the probability of lymph node metastasis was significantly greater in patients with EGFR over-expression ... activation of caspase-8 and caspase-3 Int J Oncol 2009, 34(5):1467-1473 23 Mutter R, Lu B, Carbone DP, Csiki I, Moretti L, Johnson DH, Morrow JD, Sandler AB, Shyr Y, Ye F, Choy H: A phase II study of...

Ngày tải lên: 10/08/2014, 10:21

8 435 0
báo cáo khoa học: " Correction: EGFR and COX-2 protein expression in non-small cell lung cancer and the correlation with clinical features" pps

báo cáo khoa học: " Correction: EGFR and COX-2 protein expression in non-small cell lung cancer and the correlation with clinical features" pps

... of EGFR and COX-2 protein expression Number of cases COX-2 Positive rate(%) EGFR P value Normal tissue 50 45 negative 90 0.000* COX-2 Total Positive negative positive positive negative Neoplastic ... Accepted: 28 March 2011 Published: 28 March 2011 Tissue type Number of cases COX-2 Positive rate(%) P value 0.000* positive negative Neoplastic tissue 50 45 90 Paracancerous tissue 14.3 P < 0.05 Reference ... al Journal of Experimental & Clinical Cancer Research 2011, 30:32 http://www.jeccr.com/content/30/1/32 Table (corrected table 3) EGFR expression and clinical characteristics Page of Table (corrected...

Ngày tải lên: 10/08/2014, 10:21

2 287 0
Báo cáo y học: "Semen-mediated enhancement of HIV infection is donor-dependent and correlates with the levels of SEVI" docx

Báo cáo y học: "Semen-mediated enhancement of HIV infection is donor-dependent and correlates with the levels of SEVI" docx

... post-infection as described above HIV-1 Virion-Fusion This flow cytometry-based HIV-1 virion-fusion assay was conducted as previously described [17,20] This assay is based on the incorporation of beta-lactamase-Vpr ... manufacturer Page 10 of 12 Effect of SE on DC-SIGN-mediated trans-HIV infection Seminal plasma (SE-P) was prepared by centrifugation of pooled SE for 30 at 1,000 g The supernatant was passed through ... effect of SE was relatively stable (Additional file Figure S4) and observed over a broad range of pH conditions as well as in the presence of vaginal fluid (Figure 2C-E) Our finding that SE increases...

Ngày tải lên: 13/08/2014, 01:20

12 333 0
Báo cáo y học: "Role of COX-2 in cough reflex sensitivity to inhaled capsaicin in patients with sinobronchial syndrome" ppsx

Báo cáo y học: "Role of COX-2 in cough reflex sensitivity to inhaled capsaicin in patients with sinobronchial syndrome" ppsx

... diagnosed based on symptoms (postnasal drip, nasal discharge and nasal obstruction), physical examinations and plain roentgenogram as indicated by opacities or air-fluid levels of one or more paranasal ... [2,3], as inhaled steroid therapy for bronchial asthma In our patients, diagnosis of the sinobronchial syndrome was based on the following criteria: 1) productive cough on most days for at least ... each day Control measurement of capsaicin cough threshold was carried out before the first treatment After two weeks as wash out period, treatment with etodolac and placebo was performed in a...

Ngày tải lên: 13/08/2014, 10:20

5 240 0
OReilly.Building.a.Web.2.0.Portal.with.ASP.NET.3.5.Jan.2008-BBL

OReilly.Building.a.Web.2.0.Portal.with.ASP.NET.3.5.Jan.2008-BBL

... consists of one or more activities Each activity is like a class that performs some unit task Activities use the DatabaseHelper and DashboardDataContext classes to work with the database DatabaseHelper ... real web portal in terms of its code quality, feature set, scalability, performance, and other aspects of the product, it works as a good proof of concept for several nascent technologies However, ... named DashboardFacade (see Figure 2-2) Web layer Business layer Data access layer Default.aspx Dashboard Facade Database Helper Workflows Database Context Figure 2-2 Default.aspx calls DashboardFacade...

Ngày tải lên: 15/11/2012, 14:24

310 488 1
Tài liệu Lab 2.3.2 Configuring OSPF with Loopback Addresses pptx

Tài liệu Lab 2.3.2 Configuring OSPF with Loopback Addresses pptx

... prompted for a password, enter class If that does not work, ask the instructor for assistance Router>enable At the privileged EXEC mode, enter the command erase startup-config Router#erase startup-config ... commands: Brasilia(config)#router ospf Brasilia(config-router)#log-adjacency-changes Brasilia(config-router)#end Step Test network connectivity a Ping the Brasilia router from the London router Was it ... subnet mask and default gateway Each workstation should be able to ping all of the attached routers That is because they are all part of the same subnetwork Troubleshoot as necessary Remember to assign...

Ngày tải lên: 18/01/2014, 04:20

8 380 0
Tài liệu DDR Lab Scenario 2 - Dialer Profiles with Authentication pdf

Tài liệu DDR Lab Scenario 2 - Dialer Profiles with Authentication pdf

... switch-type ? basic-1tr6 1TR6 switch type for Germany basic-5ess AT&T 5ESS switch type for the U.S basic-dms100 Northern DMS-100 switch type basic-net3 NET3 switch type for UK and Europe basic-ni1 ... user password database so we can use this information for authentication Configure the Username Password Database The first step in configuring CHAP authentication is to set up local user databases ... lab because we write erased the routers at the beginning of the lab Here is an example of how we assign the physical interface to a dialer pool A physical interface can be assigned to multiple...

Ngày tải lên: 18/01/2014, 04:20

9 329 0
Apress practical web 2 0 applications with PHP

Apress practical web 2 0 applications with PHP

... (settings.ini) [development] database.type database.hostname database.username database.password database.database = = = = = pdo_mysql localhost phpweb20 myPassword phpweb20 paths.base = /var/www/phpweb20 ... world of pixels and code was where his ideas would prosper Jeffrey has previously published articles related to print design and has contributed to award-winning graphical and Internet software ... particular aspects of development that may arise regardless of the type of application: • Chapter 1, Application Planning and Design We begin the book by looking at what defines Web 2.0, as well as looking...

Ngày tải lên: 24/01/2014, 14:07

592 1,3K 0
Tài liệu Physique Correlates with Reproductive Success in an Archival Sample of Delinquent Youth pdf

Tài liệu Physique Correlates with Reproductive Success in an Archival Sample of Delinquent Youth pdf

... is associated with muscular body types Ectomorphy; a measure of the relative dominance of linearity and is associated with thin body types Andromorphy; a measure of the relative masculinity of ... soundness of the physique as a whole,” (p.10) Thus primary structural integration can be thought of as a measure of the symmetry of the entire body Secondary structural integration; a measure of the ... dimensions of physique: Endomorphy; a measure of the relative the roundness of the physique and is associated with fat or obese body types Mesomorphy; measure of the relative dominance of muscle...

Ngày tải lên: 13/02/2014, 16:20

17 373 0
Tài liệu Báo cáo khoa học: Down-regulation of heme oxygenase-2 is associated with the increased expression of heme oxygenase-1 in human cell lines docx

Tài liệu Báo cáo khoa học: Down-regulation of heme oxygenase-2 is associated with the increased expression of heme oxygenase-1 in human cell lines docx

... oxygenase-2 down-regulates heme oxygenase-1 Y Ding et al On the other hand, it has been reported that expression of HO-1 is decreased in several types of human cell under various conditions, such as ... knockdown of HO-2 expression with each of two different siRNAs is consistently associated with increased expression of HO-1 mRNA and protein Moreover, we provide evidence 5340 that at least three ... (B), as described in Experimental procedures After 24 h of incubation, luciferase activity was measured The test promoters analyzed are shown on the left Relative luciferase activity is shown as...

Ngày tải lên: 19/02/2014, 05:20

14 488 0
Tài liệu Báo cáo khoa học: The Ets transcription factor ESE-1 mediates induction of the COX-2 gene by LPS in monocytes doc

Tài liệu Báo cáo khoa học: The Ets transcription factor ESE-1 mediates induction of the COX-2 gene by LPS in monocytes doc

... entire activation activity as the mutation of Ets sites leads to a more drastic abolition of this induction It has also been shown that the pattern of expression of PEA3 in breast cancer samples correlates ... curve was generated to identify the specificity of the PCR product For each run, serial dilutions of human GAPDH plasmids were used as standards for quantitative measurement of the amount of amplified ... combination thereof and the )170 COX-2 promoter luciferase construct Luciferase activity in the lysates was determined 16 h later, as described elsewhere [23] Data shown are means of duplicate measurements...

Ngày tải lên: 19/02/2014, 17:20

12 520 0
Tài liệu Practical Web 2.0 Applications with PHP pptx

Tài liệu Practical Web 2.0 Applications with PHP pptx

... (settings.ini) [development] database.type database.hostname database.username database.password database.database = = = = = pdo_mysql localhost phpweb20 myPassword phpweb20 paths.base = /var/www/phpweb20 ... world of pixels and code was where his ideas would prosper Jeffrey has previously published articles related to print design and has contributed to award-winning graphical and Internet software ... particular aspects of development that may arise regardless of the type of application: • Chapter 1, Application Planning and Design We begin the book by looking at what defines Web 2.0, as well as looking...

Ngày tải lên: 19/02/2014, 20:20

592 6,1K 0
Báo cáo khoa học: Membrane anchoring of diacylglycerol lactones substituted with rigid hydrophobic acyl domains correlates with biological activities ppt

Báo cáo khoa học: Membrane anchoring of diacylglycerol lactones substituted with rigid hydrophobic acyl domains correlates with biological activities ppt

... well as several other families of signaling proteins, e.g Ras guanyl nucleotide-releasing protein (RasGRPs) and chimaerins, that share with PKC the C1 domain as a DAG recognition motif Many of ... is a measure of the hydrophobic ⁄ hydrophilic balance of the molecule and is calculated by the atom-based program MOE SlogP [19] b The Ki value measures the affinity of the ligand in terms of its ... consequence of interaction of the compounds with the lipid bilayer Both Tm (maximum of DSC spectra) and DH (enthalpy change calculated from the peak areas) significantly decreased as a consequence of incubation...

Ngày tải lên: 15/03/2014, 09:20

11 336 0
Báo cáo khoa học: Structural basis for stereo-specific catalysis in NAD+-dependent (R )-2-hydroxyglutarate dehydrogenase from Acidaminococcus fermentans pptx

Báo cáo khoa học: Structural basis for stereo-specific catalysis in NAD+-dependent (R )-2-hydroxyglutarate dehydrogenase from Acidaminococcus fermentans pptx

... space group P6122 (CC of 31.5 and R-factor of 54.7%) However, the model building was hindered by the poor quality of the calculated phases A second approach was the use of heavy atom derivatives, ... model phases were combined and the autobuilding routine of ARP ⁄ WARP [52] was used to improve and expand the phases to the full resolution of the native data ˚ set (1.98 A) Model building was done ... and the release of product and cofactor ([19] and references within) In contrast to L-2-hydroxyacid dehydrogenases where the active site is shielded from solvent through the closure of the active...

Ngày tải lên: 23/03/2014, 13:20

13 456 0
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