... Biochemistry, Faculty of Sciences, University of Reims Champagne Ardenne, UMR CNRS n°6237, FranceThe activation ofpolymorphonuclear neutrophils (PMNs) constitutes the first step of phagocytosis andis ... 21March 2008, accepted 18 April 2008)doi:10.1111/j.1742-4658.2008.06474.x Oxidative functionsofpolymorphonuclearneutrophils (PMNs) , which playa deciding role in the phagocytosis process, are stimulated ... identification of lysine residues involvedin the collagen-induced activation of PMNs. The inhibition of PMN activa-tion by collagen in the presence of 6-amino-hexanoic acid, a structural ana-logue of...
... mechanism of amplification that may account formany of the biological effects of aldehydes. The zinc-releasing activity of aldehydes establishes relationships among cellular zinc, the functions of endogenous ... from oxidative stress⁄lipid peroxidation to cellular functions of zincQiang Hao and Wolfgang MaretDepartments of Preventive Medicine & Community Health and Anesthesiology, The University of ... issignificant for even relatively small increases of alde-hyde concentrations. Hence, the actions of zinc mayexplain at least some of the regulatory functions of ethanol and its metabolite acetaldehyde...
... scope, methods and design of the study. Chapter II introduces an overview of English adjectives with the definitions of adjectives and their semantic and syntactic functionsof English adjectives.Chapter ... being stupid again.In short, syntactic functionsof English adjectives are ordered clearly as in the following table:Kinds of adjectiveSemantic functionsof English adjectivesGradable non- ... opened the letter.In short, syntactic functionsof English adjectives are ordered clearly as in the following table:kinds of adjectiveSyntactic functionsof English adjectives attributive PredicativePre-modificationpost-modificationas...
... birth of the field of biochemical engineer-ing. Following on the heels of the antibiotic products was the development of efficient microbial processes for the manufacture of vitamins (riboflavin,cyanocobalamine, ... fraction of the multitude of plant secondary metabolites. Over 10,000 of these low mole-cular weight compounds are known but the actual numbers are probably in theThe Natural Functionsof Secondary ... canker of stone fruit trees and holcus spot of maize, and is also a broad-spectrum antibiotic against procaryotes andeucaryotes including Geotrichum candidum [81]. Proof of the role of antibioticsas...
... NJ(2011) The essential role of the Cu(II) state of Sco inthe maturation of the Cu(A) center of cytochrome oxi-dase: evidence from H135Met and H135SeM variants of the Bacillus subtilis Sco. ... regulation of gene expression, protection against oxidative stress,mitochondrial redox signalling, and regulation of cop-per homeostasis. It appears that the involvement of Sco proteins in each of ... variety of possible functions. Given that the fold of Sco proteins resembles that of proteins involved in thiol-disulfide redox chemistry, itis reasonable to assume that the primary role of Scoproteins...
... characteriza-tion of glycan functions [2]. A large number of glycosyltransferases (products of approximately 170genes) have been cloned [3,4], and some of their impor-tant functions have been ... in regula-tion of the conformation of integrin, determine theextent of cell migration.The mutual regulation of GnT-III and E-cadherinTo a certain degree, mutual regulation of GnT-IIIexpression ... Gu J et al.(2006) Loss of core fucosylation of low-density lipopro-tein receptor-related protein-1 impairs its function, lead-ing to the upregulation of serum levels of insulin-likegrowth...
... problem of relationships betweenhypervariability of amino acid sequences and mechanism(s) of oxidative folding. In this study, we present a comparative analysis of the foldingproperties of four ... Pathway ofoxidative folding of a-lactalbumin: a model for illustrating the diversity of disulfide folding pathways. Biochemistry 41, 8405–8413.37 Chang JY (2004) Evidence for the underlying cause of diversity ... diversity of fold-ing properties of the BPTI mutants can be compared tothat of the conotoxins studied here. The slow-rear-rangement folding of GIIIA and RIIIK and the rapid-collapse folding of PIIIA...
... andabsence of EDTA (Fig. 1). The rate of oxidation wasincreased in the presence of the LPSs of both the smoothand rough E. coli, but the rate of oxidation in the presence of the LPS of smooth ... comparison of the auto-oxidation of cross-linked Hbwith that of Hb A0is shown in Fig. 3A. The effect of thepresence of EDTA, known to bind heavy metal cations [16],on the oxidation of both ... Comparison of the effects of the LPSs of rough S. minnesota 595(Re) and smooth S. minnesota, in the absence and presence of EDTA, onthe oxidation of a, a-cross-linked Hb. Themean±SDofthreeinde-pendent...
... thatMnv−2pdvolg≤ C.(3.14)Proof. This is Lemma 4.3 of [CGY02b] (see also Lemma 4.1 of [Gur93]).This completes the proof of Proposition 3.3.Remark.Ifu ∈ C2is a Γ-admissible solution of (1.13), then by ... ωnis the volume ratio of Euclideanspace.Proof. The proof is based on a construction of the geometric tangent conecorresponding to the end N1, as follows. Take any sequence of numbers risuchthat ... B(x0,ρ/2).An important feature of (1.19) is that both sides of the inequality havethe same homogeneity under the natural dilation structure of equation (1.18);see the proof of Lemma 3.1 and the remark...
... 20 lL of reaction mix-ture, MeMIH-B DNA template was mixed with appropriateamounts of nuclease-free water, 2 lLof10· T7 reactionbuffer, 2 lL of ATP solution, 2 lL of CTP solution, 2 lL of GTP ... vitellogenin-stimulatory factor of shrimp. Because of the existence of multiple forms of the CHH family neuropeptides, there may be a dis-crepancy in defining the function of many cDNAscloned using ... changes of Vg transcriptlevel in hepatopancreasFold changes of Vg transcriptlevel in ovaryFold changes of Vglevel in hemolymphFold changes of Vgcontent in ovaryFig. 3. Effect of recombinant...
... both the physiologic functions and regulation of this pathway remain lar-gely unknown. Genome sequencing of Arabidopsis andrice has revealed complex genomic organization of plant trehalose biosynthesis ... function of trehalosebiosynthesis in the regulation of starch biosynthesishas recently been revealed. Trehalose feeding wasfound to induce expression of ApL3, encoding a largesubunit of ADP-glucose ... vitro functionality of its translated prod-uct. We also describe unique kinetic and biophysicalproperties of the plant TPPs.ResultsIsolation of rice OsTPP2Completion of the rice genome sequence...
... relevance of the different functionsof customer reference marketing are beyond the scope of this study. 7. Theoretical implications The results of the study contribute to the emerging theory of ... base of similar solutions may provide some estimates of the potential value. 6. Conclusions The purpose of this study was to identify and analyze the various practices and functionsof customer ... and coded with the help of NVivo software, a program designed for qualitative data analysis. Nvivo software was used to code the interview data in the first phase of the analysis. The open...
... outgrowth (µm)400Fig. 1. Effects of T-AChE C-terminal peptides on a7-nAChR. (A) Comparison of C-terminal amino acid sequences of R- and T-AChE isoforms.Unique isoform sequences are underlined; ... tumorigenesis [32].In cultures of glial cells, oxidative stress of the typethought to occur as the final common path in neuro-degeneration, increases the influx of calcium throughL-type calcium ... addition,incubation of T548-acetylcholinesterase with activity-enhancing molecules leads to a delay of substrate inhi-bition (Fig. 3B) that is most likely indicative of involvement of the peripheral...
... phosphorylation of DPP IV in liver: evidence fora role of compartmentalized c-Src. FEBS J 273, 992–1003.31 Blom N, Gammeltoft S & Brunak S (1999) Sequence-and structure-based prediction of eukaryotic ... proteinases of theDPIV gene family. DP8 and DP9 are closely relatedpeptidases of 61% amino acid identity, and are ubiqui-tously expressed cytoplasmic molecules [7–9].The functionsof DP8 and ... the presence of ECM compo-nents. We have demonstrated that these effects areindependent of enzyme activity and of the RGDmotif in DP9.ResultsSpecific recombinant expression of DP8 and DP9AD293...