imidazoline receptors in insulin signaling and metabolic reg

Tài liệu Báo cáo " Effect of Sweet potato (Ipomoea batatas (L.) Lam) leaf extract on hypoglycaemia, blood insulin secretion, and key carbohydrate metabolic enzymes in expermentally obese and STZ-induced diabetic mice " pptx

... glucose level and plasma insulin secretion in type 2 -diabetic mice Table 3. Effect of extract fractions on blood fasting glucose and plasma insulin secretion in obese- diabetic mice Glucose ... with the control (ND mice) . Moreover, blood glucose and insulin concentration unusually increase in obese mice in comparison with the control (ND m...

Ngày tải lên : 12/02/2014, 17:20

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Tài liệu Báo cáo khoa học: Nuclear receptors in the mosquito Aedes aegypti Annotation, hormonal regulation and expression proﬁling ppt

... Vitellogenin, in the mosquito Aedes aegypti. Mol Cell Endocrinol 267, 97–105. 20 Velarde RA, Robinson GE & Fahrbach SE (2006) Nuclear receptors of the honey bee: annotation and expression in the ... reorganization of the follicular epithelium in the resulting adults [40]. DmE75A and DmE75B have been implicated in deﬁning the transition stages 8 and 9 o...

Ngày tải lên : 18/02/2014, 13:20

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Tài liệu Báo cáo khoa học: Compartmentalization and in vivo insulin-induced translocation of the insulin-signaling inhibitor Grb14 in rat liver pptx

... of Grb14 and of the Grb14 SH2 domain have allowed us to propose a model for the Grb14 IR interaction. The PIR–BPS binds as a pseudosubstrate inhibitor in the substrate- binding groove of the kinase, ... 43634377 ê 2008 The Authors Journal compilation ê 2008 FEBS 4365 Compartmentalization and in vivo insulin-induced translocation of the insulin-si...

Ngày tải lên : 18/02/2014, 18:20

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Báo cáo khoa học: E2A participates in a ﬁne control of pre-mature B-cell apoptosis mediated by B-cell receptor signaling via transcriptional regulation of survivin, IAP2 and caspase-8 genes pot

... mainly via moderate changes in amounts of the inhibitors survivin, IAP2 and ICAD (and probably FLIP). Thus, E 2A is involved in ﬁne control of pre-mature B-cell apoptosis mediated by BCR signaling ... factors, caspases, caspase-regulating factors and CAD/ICAD) mediated by PMA/ionomycin results in suppression of activities of caspase-3, caspa...

Ngày tải lên : 16/03/2014, 04:20

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Báo cáo Y học: DNA supercoiling in Escherichia coli is under tight and subtle homeostatic control, involving gene-expression and metabolic regulation of both topoisomerase I and DNA gyrase docx

... I supercoiling À e v gyrase supercoiling À e kt gyrase supercoiling À 1 e v topoisomerase I supercoiling  e kt topoisomerase I supercoiling À e v gyrase supercoiling À e kt gyrase supercoiling 4 The ... capital Cs) by the topoisomerases on supercoiling: C supercoiling gyrase  1 e v topoisomerase I supercoiling e kt topoisomerase I supercoil...

Ngày tải lên : 18/03/2014, 01:20

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Báo cáo khoa học: Colocalization of insulin receptor and insulin receptor substrate-1 to caveolae in primary human adipocytes Cholesterol depletion blocks insulin signalling for metabolic and mitogenic control doc

... [27]. Insulin receptor signalling in caveolae We next examined the functional status of caveolae- localized receptors. After incubating cells with a submax- imal concentration of insulin the insulin- induced ... the insulin receptor in caveolae. In type 2 diabetes the tissues respond poorly to insulin, exhibiting insulin resistance that can be overcome by incr...

Ngày tải lên : 23/03/2014, 12:20

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Báo cáo sinh học: "Imp-L2, a putative homolog of vertebrate IGF-binding protein 7, counteracts insulin signaling in Drosophila and is essential for starvation resistance" ppt

... functional characterization of an insulin- binding protein in invertebrates. We have identified Imp-L2 as a secreted antagonist of IIS in Drosophila. Given the sequence homology of their Ig domains, ... genetic analyses of IIS in Drosophila and Caenorhabditis elegans have not revealed a functional insulin- binding protein so far. Here, we report the identification...

Ngày tải lên : 06/08/2014, 18:21

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Báo cáo y học: "Novel anti-inflammatory role of SLPI in adipose tissue and its regulation by high fat diet" pptx

... insulin resistance, induction of SLPI locally in adipose may also play a role in the prevention of inflammation-induced insulin resistance. In summary, we have demonstrated that obesity is accompanied by increased ... anti-inflammatory role of SLPI in adipose tissue and its regulation by high fat diet. Journal of Inflammation 2011 8:5. Submit your...

Ngày tải lên : 11/08/2014, 03:20

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Báo cáo y học: " Novel anti-inflammatory role of SLPI in adipose tissue and its regulation by high fat diet" docx

... activated in adipose tissue in obesity [12,13], the induction of SLPI in adipose tissue during obesity may be influenced by the activation state of the TLRs. Higher expression of SLPI in the visceral ... Adapala et al.: Novel anti-inflammatory role of SLPI in adipose tissue and its regulation by high fat diet. Journal of Inflammation 2...

Ngày tải lên : 11/08/2014, 06:22

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Báo cáo khoa hoc:" Expression of estrogen and progesterone receptors in vestibular schwannomas and their clinical significance" docx

... immunofluorescence histochemical staining to detect estrogen- binding activity and found 1 of 8 tumors had estrogen- binding activity and the intensity of the staining was found to be much greater in ... 0 Bilateral vestibular schwannomas 3 3 Presence of cutaneous markers of Neurofibromatosis 3 3 Table 2: Summary of reported series of expression of estrogen and...

Ngày tải lên : 11/08/2014, 07:21

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Báo cáo y học: "Early Characterization of Toll-like receptors in primary lung epithelial cells: strong impact of the TLR3 ligand poly(I:C) on the regulation of Toll-like receptors, adaptor proteins and inflammatory response" ppt

... 6, the TLR3 ligand poly(I:C) had the most potent effects on the mRNA expression of TLR adaptor proteins. Poly(I:C) induced an increased mRNA expression of the common adaptor protein MyD88 and the ... expression of other TLRs and proteins involved in TLR signaling in SAEC. In addi- tion, we demonstrate that the expression of TLRs and their signa...

Ngày tải lên : 11/08/2014, 08:21

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Báo cáo y học: " Signaling and regulation of G protein-coupled receptors in airway smooth muscle" ppsx

... contractile sensitization [69,70] and actin polymerization [40] strongly suggest a physiologic role for G 12/13 signaling in ASM. Regulation of GPCR signaling Signaling by GPCRs is a highly regulated process. ... analyzing GPCR signaling in ASM Models for analyzing GPCR signaling in ASM run the spectrum of integrative to reductionist approaches, each having certain adv...

Ngày tải lên : 13/08/2014, 13:20

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ROLE OF ADENOSINE A1 RECEPTORS IN NATIVE CORONARY ATHEROSCLEROSIS, IN-STENT STENOSIS, AND CORONARY BLOOD FLOW REGULATION IN METABOLIC SYNDROME AND EXERCISE

... ABSTRACT Xin Long ROLE OF ADENOSINE A1 RECEPTORS IN NATIVE CORONARY ATHEROSCLEROSIS, IN- STENT STENOSIS, AND CORONARY BLOOD FLOW REGULATION IN METABOLIC SYNDROME AND EXERCISE Adenosine is ... of coronary in- stent stenosis in metabolic syndrome. xvi Figure 3.3. Contribution of adenosine A1 receptor (A1R) to coronary...

Ngày tải lên : 24/08/2014, 13:30

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imidazoline receptors in insulin signaling and metabolic regulation

... I 1 -imidazoline binding and cell signaling and the mechanisms linking this signaling protein to regulation glucose metabolism. IRAS is a gene candidate for the I 1 -imidazoline receptor. To investigate ... of SHROB in both insulin cell signaling and glucose metabolism. These changes in adipose tissue very likely contribute to the overall insulin sensitizing effect...

Ngày tải lên : 13/11/2014, 10:20

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