roles of oxidative stress and redox regulation in atherosclerosis

... Processing’ 113 and 75 proteins were involved in translation and folding, sorting and degradation of ‘Genetic Information Processing’ respectively In ‘Metabolism subcategory’, large proportion of ... differentially in DS compared with those in IS including 36 unknown proteins and 213 identified proteins, and 319 differential proteins in MS compared with those in DS Strikingly, nearly half of quantified ... revealed the roles of oxidative stress and antioxidant defensing system in sclerotia formation of Polyporus umbellatus Bing Li1, Xiaofang Tian2, Chunlan Wang1, Xu Zeng1, Yongmei Xing1, Hong Ling1, Wanqiang Yin3,

Ngày tải lên: 19/03/2023, 15:29

... creatinine] Figure 1 Levels of 1-OHP, 8OHdG and reducing species in urine. Concentrations of 1-OHP (a), 8OHdG (b) and reducing capacity (c) in urine samples of workers, presented as a function of ... smoking status and time of sampling. Concentrations are expressed as μmol/mol creatinine for 1-OHP, μg/g creatinine for 8OHdG, and μW/g creatinine for the reduced species. Horizontal line in the ... response of the organism to particle-induced oxida- tive stress. The observed increase of reducing species in urine would mirror an increased level in blood originat- ing from a response to oxidative

Ngày tải lên: 20/06/2014, 00:20

... from NON-HMT and HMT13) and stock of FDI in coastal provinces are much larger than those in interior provinces. One of the interesting things is while in coastal provinces the mean of the number of NON-HMT ... NON-HMT and HMT13) and stock of FDI in coastal provinces are much larger than those in interior provinces One of the interesting things is while in coastal provinces the mean of ... overview of FDI in China, we can see that FDI in China is characterised by uneven distribution between coastal provinces and interior provinces, the dominance of FDI inflows from Hongkong, Macau and

Ngày tải lên: 16/10/2015, 15:35

... funding body had no role in the design of the study and collection, analysis, and interpretation of data and in writing the manuscript Availability of data and materials All the data is contained ... potential against CP-induced testicular toxicity and these results are in agreement of other investigated parameters seminiferous tubules and interstitium, and decreased thickness of germinal epithelium ... concentration of T, LH and FSH are highly susceptible to oxidative stress induced by CP as shown in Table 2, indicating that CP administration altered the secretion of pituitary and gonadal hormones CP inoculation

Ngày tải lên: 23/07/2020, 23:46

... positive interaction effect in combining focused, internal and diversifying, alliance-based knowledge development, and a negative interaction effect in combining diversifying, internal and alliancebased ... experience of social integration, but especially by the necessity of continuing professional culture and professional integration competence (Dandara, 2014) Engaging in lifelong learning activities ... have to provide training services and the existing training programs with their faculties and students in order to 79  The Roles of Lifelong Learning and Knowledge Management in Global Higher

Ngày tải lên: 11/10/2022, 07:30

... expression levels of IFN-γ and TNF-α in vivo compared to CIK cell stimulated with IL-2 alone [8] In order to identify the roles of IL-2 and IL-15 during induction of tumor toxic function of CIK cells, ... antibody against CD3 (OKT3) and interleukin-2 in the following days [3] During the generation of CIK cells, monoclonal antibody against CD3 provided mitogenic signals to T lymphocytes Priming with ... stimulated with combination of IL-2 and IL-15 exhibited enhanced cytotoxic capacity against lung cancer both in vitro and in vivo Interestingly, we found that CIK cells activated with IL-2 and IL-15 could

Ngày tải lên: 02/11/2022, 10:42

... grant numbers of 21276038 and 21076040, and the Open Research Fund from the Key Laboratory of Biofuel of Chinese Academy of Sciences in Qingdao Institute of Bioenergy and Bioprocess Technology ... ethanol produced during fermentation and its inhibition in yeast cells rather than osmotic stress exerted by glucose remained within the system is one of the main reasons for triggering the process ... exploring the gene expression and intracellular metabolism of yeast cells under oscillatory conditions Based on the work, we are now investigating the transcriptomics and metabolomics profiles of

Ngày tải lên: 02/11/2022, 11:36

... tolerance in crop plants by exploring suitable strategies to manage oxidative stress and maintain cellular redox state Here, we summarize the studies linking ROS and temperature stress in plants, ... generation and site of production, role of ROS as messengers as well as inducers of oxidative damage and strategies for the development of temperature stress tolerance involving redox homeostasis in ... University, Chandigarh 160014, India Introduction Temperature stresses Temperature stresses and oxidative damage in crops Temperature stresses and redox homeostasis Plant acclimation to temperature stresses

Ngày tải lên: 19/03/2023, 15:14

... dependent roles of frontal brain regions in the maintenance of working memory NeuroImage, 9, 216-226 Sahu, A (2010) Individual differences in prospective memory: the roles of handedness and interhemispheric ... system - friends in the department and across the globe, who extended a helping hand and a listening ear when in need; and family members for their continued faith in me iv Table of Contents Abstract ... combined fMRI and DTI examination of functional language lateralization and arcuate fasciculus structure: Effects of degree versus direction of hand preference Brain and Cognition, 73, 85-92 Qin,

Ngày tải lên: 20/06/2023, 15:39

... prevalence of metabolic syndrome and its complications are being increasingly recognised The intake of high amounts of fructose and fat is likely to lead to a constellation of abnormalities including insulin ... which curcumin decreases the oxidative stress remains unclear Hence, the present study was carried out to investigate the effect of curcumin on oxidative stress and redox- sensitive kinases in high ... was carried out to investigate the effects of curcumin on oxidative stress and redox- sensitive kinases in high fructose- and high-fat-fed rats Sixty rats were randomly divided into six groups with

Ngày tải lên: 01/11/2022, 09:55

... provides insight into the involvement of oxidative stress in the pathogenesis of OA from the viewpoint of oxidative stress induced genomic instability, especially telomere erosion, and chondrocyte ... senescence Our findings clearly show the presence of oxidative stress in degenerating cartilage, and the resultant telomere erosion and dysfunction of chondrocytes in vitro and in vivo, suggesting a role ... maintain the chondrocyte telomere length and proteoglycan remaining in the cartilage explants, suggesting that oxidative stress induces chondrocyte telomere instability and catabolic changes in

Ngày tải lên: 09/08/2014, 06:22

... responsible for CSE induced pro-inflammatory cytokine release Our findings in SAEC gain credence from previous studies in human subjects wherein an increased expression of NF- Page 18 of 20 (page number ... cigarette smoking can result in destruction of the alveolar wall, leading to airway enlargement Moreover, increased oxidative stress can trigger proinflammatory cytokines, which are increased in the ... mediators It is also involved in the progression of tissue injury during inflammatory conditions, implicating the role of airway/airspace epithelium in the pathogenesis of inflammatory airway

Ngày tải lên: 12/08/2014, 16:20

... pro-apoptotic activity of Bax and Bak by preventing the binding of these proteins to anti-apoptotic Bcl-2, suggesting that these pro-apoptotic proteins kill by binding and inhibiting their anti-apoptotic ... -regulation and increased involvement of COX Va and Vb in a variety of cancers Autocrine gastrins-induced up -regulation in COX Vb resulted in decreased cytochrome c release and ... leading to cytochrome c release (Mihara, Erster et al. 2003). Interestingly, this was achieved in the absence of a BH3 domain in p53, instead p53 binds to Bcl-2 using its proline-rich domain (Mihara,

Ngày tải lên: 14/09/2015, 08:42

... or the C-terminal domain (Figure 4B). We further delineated the interacting domains by subcloning the individual DNA-binding domain and linker domain. The immunoprecipitation/blotting experiment ... Mapping of the interacting regions of Stat3 and GRIM-19. (A) Schematic diagram of Stat3 indicating its functional domains speci®ed according to the amino acids (aa). (B and C) Identi®cation of interacting ... observed in full-length Stat3. On the other hand, Stat3 proteins containing either the DNA-binding and linker domains (ST3-DB.LK), or the SH2 and C-terminal domains (ST3-SH2.CT) localized mainly in

Ngày tải lên: 15/09/2015, 17:10

... stem cells (hMSCs) in fact are able of self-renewal and multi-lineage differentiation and the equilibrium between these two events determines the stem cell fate and their roles in the human body ... contribute significantly to DNA damage and cellular senescence [28-30] According to the free radical or oxidative stress theory of aging [31], oxidative stress incurs when the cellular antioxidant ... appear to efficiently handle oxidative stress, nevertheless they undergo premature senescence in vitro when exposed to H2O2 [32,33] Understanding hMSC behavior in oxidative stress would be important

Ngày tải lên: 15/01/2020, 02:05

... control of bacterial and fungal diseases of fruits, vegetables, nuts and field crops, algae in domestic lakes and ponds and in gardening as powder and spray [13, 14] In India, copper also enters in ... fragmented DNA in brain and hippocampus of coppertreated mice and rats [54, 55] Our findings suggest the ability of flubendiamide and copper to interact with double-stranded DNA (dsDNA) and induce cellular ... Essential roles of receptor-interacting protein and TRAF2 in oxidative stress- induced cell death Mol Cell Biol 2004;24: 5914–22 Gaetke LM, Chow CK Copper toxicity, oxidative stress, and antioxidant

Ngày tải lên: 30/05/2020, 21:22

... Levels of oxidative stress markers in relation to severity of sucking lice infestation in buffaloes Moreover, serum mineral profile including iron, magnesium, zinc and copper were estimated using ... bubaline pediculosis according to the level of severity of infestation Remarkably increased oxidative stress and mineral imbalance were observed in sucking lice infested buffaloes Increased mast cell ... pediculosis on buffalo health in context of oxidative stress and mineral imbalance and immuno regulations are equally important and remain less explored Accumulating evidence indicates a close bidirectional

Ngày tải lên: 20/09/2020, 19:30

... studies of inactive and active Src, the SH2 and SH3 domains are believed to form a ‘regulatory apparatus’. Binding of the phos- phorylated C-terminus to the SH2 domain and ⁄ or binding of the SH2-kinase ... demonstrated that intra-domain interactions between Src family kinases (SFKs), stabilized by binding of the phosphorylated C-terminus to the SH2 domain and ⁄ or binding of the SH2 kinase linker to the ... results in blocking of the binding of the SH2 domain to the substrate and thereby preventing interaction of the substrate with the kinase domain. For active n-Src in which the C-tail tyrosine was...

Ngày tải lên: 06/03/2014, 01:20

... becoming involved in solving major operational problems, serving on the board of directors, finding and hiring managers, occasionally replacing poorly performing managers, and assisting the firm in forming ... important aspect of small business finance the financial intertwining of owners and their businesses (Ang 1992). Outside investors and intermediaries often put considerable weight on the financial conditions ... is intermediated.lc Venture capitalists perform the quintessential functions of financial intermediaries, taking funds from one group of investors and redeploying those funds by investing in informationally...

Ngày tải lên: 15/03/2014, 21:20

... composed of 33 exons coding for a protein of 165 kDa, containing a class II (purF)-type glutaminase domain and short regions for binding to FMN and iron sulfur center. GLT is composed of 20 Amino ... (ORN), citrulline (CIT) and arginine (ARG) contents in leaves of Arabidopsis plants cultured with 5 m M nitrate in air. (F) Ornithine, citrulline and arginine contents in leaves of Arabidopsis ... 5.8-fold increase in arginine relative to the wild-type plants in air, whereas in high CO 2 , arginine remained at a wild-type level, indicating that the high level of photorespiratory ammonium was in part...

Ngày tải lên: 30/03/2014, 01:20