... These factsstrongly suggest the involvement of the enzyme, GGR, in the biosynthesis of membrane lipids in the hyper-thermophilic archaeon A. fulgidus, as predicted in the previous publication. ... archaeal reductase FEBS Journal 274 (2007) 805814 ê 2007 The Authors Journal compilation ê 2007 FEBS 807 Geranylgeranyl reductase involved in the biosynthesis of archaeal membrane lipids in the hyperthermophilic archaeon ... althoughweakly, on the geranylgeranyl group of GGGP andGGPP. These facts strongly suggest the involvement of the enzyme, A. fulgidus GGR, in the biosynthesis of membrane lipids. ResultsRecombinant expression...