Báo cáo sinh học: "Regulatable systemic production of monoclonal antibodies by in vivo muscle electroporation" docx

... expressed in none of the mice treated with the saline solution or with tetO-Tg10 alone (not shown). Similarly, in the presence of Dox in the drinking water, Tg10 was detected in none of the mice ... Modulation of erythropoietin delivery from engineered muscles in mice. Hum Gene Ther 1997, 8:195-204. 34. Bohl D, Salvetti A, Moullier P, Heard JM: Control of erythropoie- tin...

Ngày tải lên: 14/08/2014, 19:22

... between strains and is an important tool in the investigation of the spread of infec- tious diseases [4]. Such molecular fingerprinting methods to compare strains can provide useful information ... predispos- ing factors. Line removal seemed important in the successful management of line-associated infection, though the numbers investigated were small. Of the 22 cases where the cl...

Ngày tải lên: 08/08/2014, 19:20

... errors. Assuming that the main cost of reproduction is the time consumed by the male in discerning the sex of potential mates, increasing the number of mountings per unit ... by selection in either direction. In the same testing conditions of this experiment, inbreeding has been shown to enhance the rate of homosexual copulation by...

Ngày tải lên: 09/08/2014, 18:21

... no inherent interest. Its study may permit the choice of a strategy for precision increase, either by connectedness increase or by an increase of the amount of information ... Lalo6 (1993) introduced the concept of generalized coefficient of determination (CD), the CD of a linear combination of genetic values, and suggested a new defin...

Ngày tải lên: 09/08/2014, 18:22

... proposed to use a non-linear function to model indi- vidual production curves in dairy cattle. The parameters of this function have biological interpretation in terms of peak of production and persistency, ... each part of the time period. Analysis of the protein yield data in dairy cattle confirmed these results since QTL with high effect at the beginning or the end of th...

Ngày tải lên: 14/08/2014, 13:22

... entropy of activation in the case of the wild-type enzyme. In principle, the entropy of inactivation consists of two parts: the increased configurational entropy due to partial unfolding of the protein ... purposes. This incompatibility often relates to the stability of the enzymes under body conditions. In the case of engineering proteins for thermostability, researchers a...

Ngày tải lên: 30/03/2014, 02:20

... rodent spine in flexion-extension testing. Incorporating the same metho- dologyusedinhumanspinetesting,wewereableto assess spinal fusion in the rodent model. In humans, quality of spinal fusions ... detected by palpationinflexion-extension testing of a rabbit model [30]. In their experiment, with the absence of a carrier for injected induction proteins, the location of bony...

Ngày tải lên: 20/06/2014, 04:20

... rodent spine in flexion-extension testing. Incorporating the same metho- dologyusedinhumanspinetesting,wewereableto assess spinal fusion in the rodent model. In humans, quality of spinal fusions ... induced in ten mice spine using a previously described technique of in situ endochondr al ossification, harvested with soft tissue, and cast in radiolucent alginate material for ha...

Ngày tải lên: 20/06/2014, 07:20

... differentiation of T H 17 cells, and more importantly, in inducing them to secrete the cytokine interleukin (IL)-22 (a cytokine impli- cated in the defense of mucosal barriers). AhR-dependent induction of ... for instance, in the development of the nervous system in Caenorhabditis elegans, while in Drosophila the AhR homolog spineless is involved in development of a...

Ngày tải lên: 06/08/2014, 19:21

... the shedding of clumps of biofilm [27-29]. Biofilm formation in the wet part of the production and the shedding of clumps of biofilm into the bags with the Dent-O-Sept swab can explain why P. aeruginosa ... contaminated with P. aeruginosa and the finding of the outbreak strain in the production line makes it highly unlikely that the swabs were contaminated after sealing th...

Ngày tải lên: 08/08/2014, 19:20