Textbook of Interventional Cardiovascular Pharmacology - part 7 docx

... and low levels of transgene expression limit this approach. Phospholipid formulae such as 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine-N-dode- canoyl/1,2-dioleoyl-sn- glycero-3-phosphocholine ... intramuscular injec- tion of recombinant adeno-associated virus-erythropoietin in monkeys. J Surg Res 2000; 90(2):102–108. 57 Hirata RK, Russell DW. Design and packaging of adeno-associ- ate...

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... product of the lipoxyge- nase pathway, 5-oxo-6,8,11,14-eicosatetraenoic acid (5-Oxo-ETE), induces leukocyte chemotaxis and inflamma- tion. 5-Oxo-ETE is formed by the oxidation of 5S-hydroxy-ETE (5-HETE) ... Control PRISM ( 17) Tirofiban 3232 Death, 48 hr 3.8 5.6 0.68 0. 37 0. 37 1.00 x 48 hr MI, RA 30 day 15.9 17. 1 (0.48–0.93) (0.32–3.09) 0.93 (0.80–1.09) PRISM-PLUS Tirofiban 1915 Dea...

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... anticoagulation. In the XANADU-ACS trial (77 ), 402 patients with ACS were randomized to unfractionated heparin, low-dose DX-9065a, or high-dose DX-9065a. The primary end-point was the compos- ite of death, MI, ... activity of whole- blood clots. J Clin Invest 1993; 91:1 877 –1883. 55 McKenzie CR, Abendschein DR, Eisenberg PR. Sustained inhi- bition of whole-blood clot procoagulant acti...

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... systems (9,10). Removal of fibrinopeptide A leads to end-to-end fibrin poly- merization whereas loss of fibrinopeptide B allows side-to-side polymerization of the end-to-end linked monomers (11). ... two months. (See p. 273 .) xxvi 1180 FM 3/15/ 07 6: 57 PM Page xxvi Textbook of Interventional Cardiovascular Pharmacology Nicholas N. Kipshidze FACC FESC FSCAI Professor of...

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... 0.32 9.1 Ϯ 0.41 7. 6 Ϯ 0.24 ␤ -carotene (RE) b 377 Ϯ 36.4 5 37 Ϯ 51.4 559 Ϯ 47. 3 522 Ϯ 69.0 554 Ϯ 47. 3 5 07 Ϯ 34.2 A (RE) b 878 Ϯ 40.6 1115 Ϯ 80.2 11 17 Ϯ 61.5 961 Ϯ 74 .4 945 Ϯ 52.8 9 97 Ϯ 58.5 Note: ... 11.3 7. 27 0 .72 6 At 270 days 32 .7 Ϯ20.15 55 .76 Ϯ25.01 0.001 Lesion length (mm) 13.35 Ϯ6.33 12 .79 Ϯ4.28 0.144 Stent length (mm) 15 .7 Ϯ2.62 16 Ϯ2 .78 0.149 Net gain (mm) 0....

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... family of peptides (VEGF-A to -E) of which VEGF-A is the most thoroughly stud- ied. VEGF-A (more often called just VEGF) occurs in five isoforms of 121, 145, 165, 189, and 206 amino acids. VEGF- C ... gelatin Membrane-type (MT-MMPs) MT1-MMP MMP-14 Collagen types I–III, fibronectin, laminins, vitronectin, proteoglycans; activates proMMP-2 MT2-MMP MMP-15 Activates proMMP-2 MT3-MMP MMP-16...

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... Investigators. N Engl J Med 1992; 3 27: 669– 677 . 87 The-Acute-Infarction-Ramipril-Efficacy-(AIRE)-Study- Investigators. Effect of ramipril on mortality and morbidity of survivors of acute myocardial infarction ... failure: analysis of the experience in the MERIT-HF study. J Am Coll Cardiol 2001; 38:932–938. 29 The-Beta-Blocker-Evaluation -of- Survival-Trial-Investigators. A Trial...

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... necrosis factor (TNF), alpha-induced protein 3 77 0859 ITGB5 Integrin, beta 5 77 6636 BHMT Betaine-homocysteine methyltransferase 78 278 9 AVPR1A Arginine vasopressin receptor 1A 78 5 975 F13A1 Coagulation ... interventions 100 80 60 40 20 0 02468 10 0246810 Years 2,0 07 1,605/ 1,393/ 1,145/ 859/ 616/ 92.5 88.0 83.1 76 .3 71 .2 2,0 07 1,601/ 1,3 47/ 1,104/ 879 / 662/ 93.0 87. 9 82.2...

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... mean 15–20 8 hr (2,12) of 40 hrs (1); min (7) dose-dependent, 47 hr for 5 mg dose (15) For vitamin K dependent clotting factors: II-60 hr, VII-4–6 hr, IX-24 hr, X-4 8 -7 2 hr (1) Return to 4–5 ... capacity in patients with hyper- trophic obstructive cardiomyopathy. Eur Heart J 2000; 21 :77 0 77 7. 37 Shamim W, Yousufuddin M, Wang D, et al. Nonsurgical reduc- tion of the interve...

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... (18) 2000 Self-designed PFM-P75 Pig coronary Ibuprofen 10–15 µg PFM-P75 No art in 5% (g/g) Valsartan 20–25 µg PFM-P75 No in 10% (g/g) De Scheerder (18) 2000 Self-designed PFM-P75 Pig coronary ... arteries. Circulation 2002; 106( 17) :2 271 –2 277 . 52 Meerkin D, Tardif JC, Bertrand OF, et al. The effects of intra- coronary brachytherapy on the natural history of postangioplasty dissectio...

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