Báo cáo khoa hoc:" Role of metabolically active hormones in the insulin resistance associated with short-term glucocorticoid treatment" doc
Báo cáo khoa hoc:" Role of metabolically active hormones in the insulin resistance associated with short-term glucocorticoid treatment" doc
... of 5
(page number not for citation purposes)
Journal of Negative Results in
BioMedicine
Open Access
Brief report
Role of metabolically active hormones in the insulin resistance
associated with ... CA).
Insulin sensitivity was assessed using the homeostatic
model (HOMA-S), which is directly related to fasting
insulin and glucose levels [13]. A weighted combin...
Tài liệu Báo cáo khoa học: Role of K22 and R120 in the covalent binding of the antibiotic fosfomycin and the substrate-induced conformational change in UDP-N-acetylglucosamine enol pyruvyl transferase docx
... also involved in fosfomycin
binding, and in view of the multitude of interactions, it was
assumed that deletion of a single interaction would not lead
to a complete loss of fosfomycin binding. Therefore ... form of the protein.
The results obtained with the K22V/R120K double
mutant protein point toward a central role of arginine 120
in the conformational proces...
Báo cáo khoa học: Role of DptE and DptF in the lipidation reaction of daptomycin ppt
... by
the C domain of the initiation module of dapto-
mycin. That DptE and DptF are involved in the
lipidation process of daptomycin was first shown by
Miao et al. [1]. In their work, the daptomycin ... group of Thr4 and the C-terminal
Kyn13, resulting in a ten-membered ring [8]. More-
over, several ORFs localized within the gene cluster
are associated with the bio...
Báo cáo khoa học: Role of calcium phosphate nanoclusters in the control of calcification pot
... used to describe the binding
isotherms obtained previously for the b-casein 1–25 phos-
phopeptide in this pH range, and the same model was
adapted to fit the binding isotherm of OPN 1–149 mea-
sured ... sequences found in
SPs with known involvement in mineralization are
shown in Table 1, and aligned sequences of their
orthologues are given in Doc. S2 (see Supporting in...
Báo cáo khoa hoc:"Association of a missense mutation in the bovine leptin gene with carcass fat content and leptin mRNA levels" pps
... diabetes insipidus in a patient. On substitution of the arginine for serine
instead of cysteine, binding capacity and function returned to wild-type levels
indicating the importance of the cysteine ... sparse,
leptin appears to be an important component of a feedback loop involving key
metabolic regulators including insulin, glucocorticoids and the sympathetic
nervous syste...
Tài liệu Báo cáo khoa học: Role of cleavage and shedding in human thyrotropin receptor function and trafficking pdf
... concentration of the biotinylated Ig remaining
on the cell surface was then quantified by measuring the
binding of [
125
I]Streptavidin. In the absence of bTSH, a very
weak internalization of the TSHR ... were incubated at 4 °C with the Ig in the presence
or in the absence of bTSH. After washing the unbound Ig, the
cells were incubated for different period...
Báo cáo khoa học: Role of disulfide bonds in goose-type lysozyme potx
... states of the protein [49].
The thermal unfolding of the wild-type protein has
been investigated using CD and fluorescence spectros-
copy, and led to the observation that the unfolding
transition of ... to the observed
DDG value for the Cys-free mutant ()6.14 kcalÆmol
)1
).
These results suggest that the increase in entropy of
the unfolded state is a dominant factor...
Báo cáo khoa học: "Role of mucosal mast cells in visceral hypersensitivity in a rat model of irritable bowel syndrome" ppt
... between vicinity of MMC to nerves and the severity
of abdominal pain/discomfort symptom of IBS [3]. These
findings, together with our current observation, suggest that
the degranulation of MMC is ... test.
Results
The number of MMC in distal colon
In the toluidine blue-stained colonic specimens, MMC
was easily identified in the lamina propria. The mean
number of...
báo cáo khoa học: "Role of Wnt canonical pathway in hematological malignancies" pps
... activated.
Activation of Dvl induces the dissociation of GSK-3b from
Axin and leads to the inhibition of GSK-3b. Next, the
phosphorylation and degradation of b-catenin is inhibited
as a result of the inactivation ... dissociation of GSK-3b from Axin and leads to the inhibition of GSK-3b. Next, the
phosphorylation and degradation of b-catenin is inhibited as a resul...
Báo cáo khoa học: Deamidation of labile asparagine residues in the autoregulatory sequence of human phenylalanine hydroxylase potx
... carbonyl
of Asn by the nitrogen of the peptide group linking the
Asn to the following residue [4–6]
2
. As hydrolysis of this
intermediate may occur on either side of the imide
nitrogen, the Asp ... discrepancies between the
different unit cells in the crystal. Combining the crystal
structure information with the results of this study, we
conclude that the...