The Biology of NKT Cells Albert Bendelac - part 3 pptx

... only. ANRV306-IY2 5-1 2 ARI 11 February 2007 12:20 49. Yamaguchi Y, Motoki K, Ueno H, Maeda K, Kobayashi E, et al. 1996. Enhanc- ing effects of (2S,3S,4R )-1 -O-(α-D-galactopyranosyl )-2 -( N-hexacosanoylamino )-1 ,3, 4- octadecanetriol ... constitutive autoreactive recognition of iGb3 through the secretion of IFN-γ (indirect microbial recognition). www.annualreviews.org •...

Ngày tải lên: 10/08/2014, 03:20

... by the rar- ity of iGb3 and the dominance of the regioiso- mer Gb3. Furthermore, other than the enzy- matic pathways of synthesis and degradation, little is known about the general biology of iGb3, ... wall of Sph- ingomonas, a Gram-negative, LPS-negative member of the class of α-proteobacteria ( 53, 54). These glycosphingolipids are responsi- ble for the strong...

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... by the autoreac- tive IL-2 response of NKT hybridomas to DP thymocytes (18) and by the proliferative and cytokine response of fresh NKT cells to synthetic iGb3 (26). The other reason is that the ... difference between the development of NKT cells and that of conventional T cells. Furthermore, during these stages a DN pop- ulation arises by downregulation of CD4...

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... for Vα14 NKT cells in IL-12-mediated rejection of tumors. Science 278:16 23 26 196. Park SH, Kyin T, Bendelac A, Carnaud C. 20 03. The contribution of NKT cells, NK cells, and other γ-chain-dependent ... Extravascular T-cell recruitment requires initiation begun by Vα14 + NKT cells and B-1 B cells. Trends Immunol. 25:441–49 www.annualreviews.org • Biology of NKT Ce...

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... across a prosthetic valve depends upon the type, size, and position of the prosthesis as well as the cardiac output; guidelines are available for the ac- ceptable range of Doppler gradients ... Assessment of mechanical prosthetic malfunction is more difficult with TTE because acoustic shadowing caused by the pros- thetic material may limit transthoracic visualiza- tion of pros...

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... erosion. The speed of the horse, in other words, allows the Amish to pay attention to the minute particulars of their farm and how they farm. By a similar logic, he waits to cut hay until the bobolinks ... wisdom. In large part the difference, whether they thought about it or not, was the speed of the society. It is time to consider the possibility that, for the mo...

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... condition and weaken the public mind. The exercise of their economic power cre- ates dependencies that undermine public resolve. Their sheer perva- 92 THE POLITICS OF DESIGN the terms of the law should ... and the poor. They cannot find the wherewithal to defend the public in- terest in matters of global trade or even in the financing of public elec- 11 Conservation...

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... limitations of genetic testing in the management of Chapter 064. The Practice of Genetics in Clinical Medicine (Part 1) Harrison's Internal Medicine > Chapter 64. The Practice of Genetics ... for example, the concordance rate in monozygotic twins ranges between 50 and 90%. Diabetes or impaired glucose tolerance occurs in 40% of siblings and in 30 % of t...

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... members. The determination of risk for an asymptomatic individual will vary depending on the size of the pedigree, the number of unaffected relatives, and the types of diagnoses, as well as the ... mutations would greatly impact the cost of testing without significantly influencing the effectiveness of mass screening. Nevertheless, the individual who carries...

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