MELANOMA CRITICAL DEBATES - PART 7 ppt

MELANOMA CRITICAL DEBATES - PART 7 ppt

MELANOMA CRITICAL DEBATES - PART 7 ppt

... al. DTIC (NSC-45388) and combination therapy for melanoma. I. Studies with DTIC, BCNU (NSC-409962), CCNU (NSC -7 9 0 37) , vincristine (NSC- 675 74), and hydroxyurea (NSC-32065). Cancer Treat Rep 1 976 ; 60: ... vincristine with two dose schedules of 5-( 3,3-dimethyl-1-triazino) imidazole 4- carboxamide (DTIC) in the treatment of disseminated malignant melanoma. Cancer 1 975 ; 35: 36...

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MELANOMA CRITICAL DEBATES - PART 1 ppt

MELANOMA CRITICAL DEBATES - PART 1 ppt

... published 2002 Library of Congress Cataloging-in-Publication Data Melanoma: Critical Debates /edited by J. A. Newton Bishop, M. Gore. p. cm. ISBN 0-6 3 2-0 577 2-6 1. Melanoma. I. Bishop, J. A. Newton (Julia ... Newton (Julia A. Newton) II. Gore, Martin [DNLM: 1. Melanoma. QZ 200 C4 37 2001] RC280.M 37 C48 2001 616.99¢ 477 —dc21 2001035202 ISBN 0-6 3 2-0 577 2-6 A cata...

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MELANOMA CRITICAL DEBATES - PART 3 pptx

MELANOMA CRITICAL DEBATES - PART 3 pptx

... FEBS Lett 19 97; 418: 87 90. 74 Stevenson C, Davies RJH. Photosensitisation of guanine-specific DNA damage by 2-phenylbenzimidazole and the sunscreen agent 2-phenyl- benzimidazole-5-sulfonic acid. ... familial atypical multiple-mole melanoma (FAMMM) syndrome families. Melanoma Res 1995; 5: 169 77 . 28 Tucker MA, Fraser MC, Goldstein AM, et al. The risk of melanoma and other cancers i...

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MELANOMA CRITICAL DEBATES - PART 5 ppt

MELANOMA CRITICAL DEBATES - PART 5 ppt

... 34: 971 –8. 28 Rampen FHJ, van Huystee BEWL, Kiemeney LALM. Melanoma/ skin cancer screening clinics: experiences in the Netherlands. J Am Acad Dermatol 1991; 25: 77 6 7. 29 Rampen FH, Casparie-van ... during follow-up in asymptomatic pa- tients with normal physical examinations. Of these, 67 were false-positive and only two bipedal lymphangiograms were true-positive. Over a median follow-...

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MELANOMA CRITICAL DEBATES - PART 10 pptx

MELANOMA CRITICAL DEBATES - PART 10 pptx

... of melanoma 273 –4 melanoma and effects on baby 276 melanoma during 274 –5 treatment of melanoma during 275 –6 prevacation tan from sunbed use 25 procarbazine 178 prognosis in women 269 70 pro-opiomelanocortin ... 198–200, 199 high-dose 199 low-dose 199–200 trials in stage II 200–1 g-interferon 1 97, 233, 234, 243 interleukins IL-2 195, 1 97, 222, 238, 243 IL-4 243 IL-10 243 IL-12...

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MELANOMA CRITICAL DEBATES - PART 2 pdf

MELANOMA CRITICAL DEBATES - PART 2 pdf

... Norway 1 974 75 78 /131 2. 27 (1.3–4.1) ≠ Graham et al. [42] USA 1 974 –80 404/521 2.2 (1.2–4.1) ≠ Herzfeld et al. [43] USA 1 977 79 324/415 2.58 (1.42–4.69) ≠ Beitner et al. [44] Sweden 1 978 –83 523/505 ... 523/505 1.8 (1.2–2 .7) ≠ Elwoood & Canada 1 979 –81 369/369 1.10 (0 .75 –1.62) - Gallagher [45] Holman et al. [46] Australia 1980–81 5 07/ 5 07 1.1 (0 .71 –1.60) - Holly e...

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MELANOMA CRITICAL DEBATES - PART 4 pps

MELANOMA CRITICAL DEBATES - PART 4 pps

... for the regular follow-up of selected high-risk individuals re- sults in thinner melanomas being diagnosed, as concluded from a Dutch study on high-risk patients from melanoma- prone families who ... patient (because of a high-risk profile) need regular follow-up? If so, refer to pigmented lesion clinic Part 2: Diagnosis, Screening and Prevention Melanoma: Critical Debates Edited by...

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MELANOMA CRITICAL DEBATES - PART 6 pot

MELANOMA CRITICAL DEBATES - PART 6 pot

... the detection of melanoma metastases. Ann Surg 1998; 2 27: 76 4–9; discussion 76 9 71 . 35 Macfarlane DJ, Sondak V, Johnson T, Wahl RL. Prospective evaluation of 2-[ 18F ]-2 -deoxy- D-glucose positron emission ... of 2- uoro-2-deoxyglucose (FDG)-PET scanning was re- ported for detection of melanoma metastases [33,34]. Although access to PET is at present limited, it is a promisi...

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MELANOMA CRITICAL DEBATES - PART 8 pot

MELANOMA CRITICAL DEBATES - PART 8 pot

... TGF-b [74 ,76 ] a-MSH [77 ] Shift of TH 1 TC 1 to TH 2 TC 2 IL-10, TGF-b, FasL [78 ,79 ] Inhibition of migration of PGE 2 , tumour matrix [80,81] leukocytes from blood vessels VEGF [82] Tumour-mediated ... A24, B 37, B44, DR11, DR13 MAGE-4A 55 11 22 MAGE-6 [63] 89 ? ? MAGE-12 89 ? ? MAGE-C1 [36] 37 53 BAGE 22 Cw1601 GAGE [63] 24 Cw6 LAGE [28] 50 SSX-2 [30] 43 NY-ESO-1 [29] 20–40 A2, A31 DAM...

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MELANOMA CRITICAL DEBATES - PART 9 pps

MELANOMA CRITICAL DEBATES - PART 9 pps

... antigens. The cytokines involved in the T-cell response, such as IFN-g and IL-12, help drive the T-cell response towards cell- mediated immunity, whereas IL-4 and IL-10 drive the response towards humoral ... Treatment of Cancer Melanoma Cooperative Group (EORTC-MCG). Follow-up after therapeutic isolated limb perfusion Most sensitive in-transit melanoma metastases are the superficial ‘epi...

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