... Cu releasewas clearly demons trated and release was accelerated as the pH was reduced. In vitro toxicity of CuCNPs in HeLa cellsThe toxicity of CuCNPs to cancer cells was investigated and results ... the synthesis, characterization, and metal binding properties of our Cu-binding particles, as well as preliminary in vitro toxicity in cancer cellsResultsSynthesis and characterization of Cu-loaded polymeric nanoparticles Carboxylate-function ... 25:868-873.36. Alemón-Medina R, Bre a- Valle M, Muñoz-Sánchez J, Gracia-Mora M, Ruiz-Azuara L: Induction of oxidative damage by copper-based antineoplasticdrugs (Casiopeínas). Cancer Chemoth Pharm 2007,...