Paraneoplastic Syndromes ppsx

... Chapter 096. Paraneoplastic Syndromes: Endocrinologic/Hematologic (Part 1) Harrison's Internal Medicine > Chapter 96. Paraneoplastic Syndromes: Endocrinologic/Hematologic Paraneoplastic ... homologue 1 (hASH -1), which is expressed at abnormally high levels in SCLC associated with ectopic ACTH. The activity of hASH-1 is inhibited by hairy enhancer of s...

Ngày tải lên: 07/07/2014, 04:20

... Table 96- 1 Paraneoplastic Syndromes Caused by Ectopic Hormone Production Paraneoplastic Syndrome Ectopic Hormone Typical Tumor Types a ... Hyperthyroidism Thyroid- stimulating hormone (TSH) Hydatidiform mole, embryonal tumors, struma (PGE2) (rare) Syndrome of inappropriate antidiuretic hormone secretion (SIADH) Vasopressin Lung

Ngày tải lên: 07/07/2014, 04:20

... and inflammatory mediators. Clinical Manifestations Chapter 096. Paraneoplastic Syndromes: Endocrinologic/Hematologic (Part 3) Etiology Humoral hypercalcemia of malignancy (HHM) occurs

Ngày tải lên: 07/07/2014, 04:20

... Chapter 096. Paraneoplastic Syndromes: Endocrinologic/Hematologic (Part 4) Etiology Vasopressin is an antidiuretic hormone normally ... ectopic vasopressin production are the same as those of other causes of SIADH (Chaps. 46 and 3 34). Hyponatremia and reduced serum osmolality occur in the setting of an inappropriately normal

Ngày tải lên: 07/07/2014, 04:20

... patients will eventually progress despite medical blockade. Chapter 096. Paraneoplastic Syndromes: Endocrinologic/Hematologic (Part 5) Rarely, corticotropin-releasing hormone (CRH) is produced ... adenomas but fails to suppress ectopic ACTH in ~90% of cases. Bronchial and other carcinoids are well-documented exceptions to these general guidelines, as these ectopic so...

Ngày tải lên: 07/07/2014, 04:20

... Octreotide scans may also be useful to detect these tumors. Chapter 096. Paraneoplastic Syndromes: Endocrinologic/Hematologic (Part 6) Tumor-Induced Hypoglycemia Caused by Excess Production

Ngày tải lên: 07/07/2014, 04:20

... red cell mass. If the red cell mass is elevat ed, Chapter 096. Paraneoplastic Syndromes: Endocrinologic/Hematologic (Part 7) Hematologic Syndromes: Introduction The elevation of granulocyte, ... proliferation of the myeloid elements due to the underlying disease rather than a paraneoplastic syndrome. The paraneoplastic hematologic syndromes in patients with soli...

Ngày tải lên: 07/07/2014, 04:20

... with lung and gastrointestinal cancers, 20% of patients Chapter 096. Paraneoplastic Syndromes: Endocrinologic/Hematologic (Part 8) Granulocytosis Approximately 30% of patients with solid ... 400,000/àL) have an underlying diagnosis of cancer. IL-6, a candidate molecule for the etiology of paraneoplastic thrombocytosis, stimulates the production of platelets in vitro...

Ngày tải lên: 07/07/2014, 04:20

... Chapter 096. Paraneoplastic Syndromes: Endocrinologic/Hematologic (Part 9) Clinical Manifestations Patients with cancer who develop ... Further Readings Cutaneous paraneoplastic syndromes are discussed in Chap. 54. Neurologic paraneoplastic syndromes are discussed in Chap. 97. Al-Tourah AJ et al: Paraneoplastic erythropoietin- induced ... lymphocytic lymphoma. J...

Ngày tải lên: 07/07/2014, 04:20

... in 30–50% of patients with thymoma or sclerotic myeloma. Table 97-1 Paraneoplastic Syndromes of the Nervous System Syndromes of the brain, brainstem, and cerebellum Focal encephalitis ... Paraneoplastic cerebellar degeneration Opsoclonus-myoclonus Syndromes of the spinal cord Subacute necrotizing myelopathy Motor neuron dysfunction Myelitis Stiff-person syndrome Syn...

Ngày tải lên: 07/07/2014, 04:20

... Chapter 097. Paraneoplastic Neurologic Syndromes (Part 2) Pathogenesis Most PNDs are mediated by immune responses triggered ... the resistance of many of these conditions to therapy. Table 97- 2 Paraneoplastic Antineuronal Antibodies, Associated Syndromes and Cancers Antibody Syndrome Associated Cancers Anti-Hu ... nervous system (CNS), many antibody-associated...

Ngày tải lên: 07/07/2014, 04:20

... Chapter 097. Paraneoplastic Neurologic Syndromes (Part 3) Neuronal cell-surface antigens can be the target of antibodies in some patients with paraneoplastic encephalitis. ... antigens are unknown. These include several syndromes of inflammatory neuropathies and myopathies. In addition, many patients with typical PND syndromes are antibody- negative. For still oth...

Ngày tải lên: 07/07/2014, 04:20

... Paraneoplastic Syndromes Paraneoplastic syndromes dĩ nhiên thấy trong ung thư, và có khi xuất hiện hàng tháng truớc ... ra. Oncologists nhiều khi nhận consultation từ các y sĩ khác hỏi: "bnhân mất ký, có phải paraneoplastic hay không". Những trường hợp này, tôi làm work up (đi tìm bệnh) như sau (dĩ

Ngày tải lên: 13/07/2014, 20:20

... properly cited. Primary research Outcome of crisis intervention for borderline personality disorder and post traumatic stress disorder: a model for modification of the mechanism of disorder in complex ... h from the beginning of treatment (that is, from the sub- ject's examination by a psychiatrist and formulation of a treatment...

Ngày tải lên: 08/08/2014, 23:21

... the case of a patient with small cell lung cancer and dual paraneoplastic syndromes involving adrenocorticotropic hormone and calcitonin. To the best of our knowledge, dual paraneoplastic syndromes ... paraneoplastic syndromes occur commonly, dual paraneoplastic syndromes occurring simultaneously in the same p atient are very rare. We describe the case...

Ngày tải lên: 10/08/2014, 23:22