paraneoplastic neurological syndromes symptoms

... in 30–50% of patients with thymoma or sclerotic myeloma. Table 97-1 Paraneoplastic Syndromes of the Nervous System Syndromes of the brain, brainstem, and cerebellum Focal encephalitis ... Paraneoplastic cerebellar degeneration Opsoclonus-myoclonus Syndromes of the spinal cord Subacute necrotizing myelopathy Motor neuron dysfunction Myelitis Stiff-person syndrome Syndromes ... nerve hyperexcitability Autonomic neuropathy Syndromes of the neuromuscular junction Lambert-Eaton myasthenic syndrome Myasthenia gravis Syndromes of the muscle ...

Ngày tải lên: 07/07/2014, 04:20

... Chapter 097. Paraneoplastic Neurologic Syndromes (Part 2) Pathogenesis Most PNDs are mediated by immune responses triggered ... the resistance of many of these conditions to therapy. Table 97- 2 Paraneoplastic Antineuronal Antibodies, Associated Syndromes and Cancers Antibody Syndrome Associated Cancers Anti-Hu ... cancer, other solid tumors Anti- NR1/NR2 subunits of Encephalitis with prominent psychiatric symptoms, Ovarian teratoma ...

Ngày tải lên: 07/07/2014, 04:20

... Chapter 097. Paraneoplastic Neurologic Syndromes (Part 3) Neuronal cell-surface antigens can be the target of antibodies in some patients with paraneoplastic encephalitis. ... antigens are unknown. These include several syndromes of inflammatory neuropathies and myopathies. In addition, many patients with typical PND syndromes are antibody- negative. For still other ... amyloid. Approach to the Patient: Paraneoplastic Neurologic Disorders The diagnosis and management of PNDs may be difficult for several reasons. First, it is common for symptoms to appear before the...

Ngày tải lên: 07/07/2014, 04:20

Ngày tải lên: 07/07/2014, 04:20

Ngày tải lên: 07/07/2014, 04:20

Ngày tải lên: 07/07/2014, 04:20

Ngày tải lên: 07/07/2014, 04:20

Ngày tải lên: 07/07/2014, 04:20

Ngày tải lên: 07/07/2014, 04:20

... musculoskeletal, neurological and psychosomatic symptoms (Euroquest). Results: The dental assistants reported significant higher occurrence of neurological symptoms; psychosomatic symptoms, problems ... existence of possible chronic neurological symptoms today within this working group, due to this exposure. The aim of this study was to compare the occurrence of neurological symptoms among dental assistants ... given symptoms from arms and hands as well, and the population is not quite comparable. Nevertheless, early notification of symptoms can probably not alone explain the reported neurological symptoms...

Ngày tải lên: 20/06/2014, 00:20

... 096. Paraneoplastic Syndromes: Endocrinologic/Hematologic (Part 1) Harrison's Internal Medicine > Chapter 96. Paraneoplastic Syndromes: Endocrinologic/Hematologic Paraneoplastic Syndromes: ... the prevalence of paraneoplastic syndromes indicate that they are more common than is generally appreciated. The signs, symptoms, and metabolic alterations associated with paraneoplastic disorders ... in a patient with cancer should prompt consideration of a paraneoplastic syndrome. The most common endocrinologic and hematologic syndromes associated with underlying neoplasia will be discussed...

Ngày tải lên: 07/07/2014, 04:20

... Table 96- 1 Paraneoplastic Syndromes Caused by Ectopic Hormone Production Paraneoplastic Syndrome Ectopic Hormone Typical Tumor Types a ... lung, pancreas, ovary a Only the most common tumor types are listed. For most ec topic hormone syndromes, an extensive list of tumors has been reported to produce one or more hormones. b hCG...

Ngày tải lên: 07/07/2014, 04:20

... osteolytic cytokines and inflammatory mediators. Clinical Manifestations Chapter 096. Paraneoplastic Syndromes: Endocrinologic/Hematologic (Part 3) Etiology Humoral hypercalcemia of malignancy...

Ngày tải lên: 07/07/2014, 04:20

... Chapter 096. Paraneoplastic Syndromes: Endocrinologic/Hematologic (Part 4) Etiology Vasopressin is an antidiuretic ... hyponatremia on routine chemistry testing. Symptoms may include weakness, lethargy, nausea, confusion, depressed mental status, and seizures. The severity of symptoms reflects the rapidity of onset...

Ngày tải lên: 07/07/2014, 04:20

... Unfortunately, many patients will eventually progress despite medical blockade. Chapter 096. Paraneoplastic Syndromes: Endocrinologic/Hematologic (Part 5) Rarely, corticotropin-releasing hormone...

Ngày tải lên: 07/07/2014, 04:20

... subtype 2. Octreotide scans may also be useful to detect these tumors. Chapter 096. Paraneoplastic Syndromes: Endocrinologic/Hematologic (Part 6) Tumor-Induced Hypoglycemia Caused by...

Ngày tải lên: 07/07/2014, 04:20

... underlying disease rather than a paraneoplastic syndrome. The paraneoplastic hematologic syndromes in patients with solid tumors are less well characterized than the endocrine syndromes because the ectopic ... these tumors (Table 96- 2). The extent of the paraneoplastic syndromes parallels the course of the cancer. Table 96-2 Paraneoplastic Hematologic Syndromes the serum erythropoietin level ... mass. If the red cell mass is elevat ed, Chapter 096. Paraneoplastic Syndromes: Endocrinologic/Hematologic (Part 7) Hematologic Syndromes: Introduction The elevation of granulocyte, platelet,...

Ngày tải lên: 07/07/2014, 04:20

... in 40% of patients with lung and gastrointestinal cancers, 20% of patients Chapter 096. Paraneoplastic Syndromes: Endocrinologic/Hematologic (Part 8) Granulocytosis Approximately 30% of ... 400,000/àL) have an underlying diagnosis of cancer. IL-6, a candidate molecule for the etiology of paraneoplastic thrombocytosis, stimulates the production of platelets in vitro and in vivo. Some ... advanced-stage disease are more likely to have granulocytosis than those with early-stage disease. Paraneoplastic granulocytosis does not require treatment. The granulocytosis resolves when the...

Ngày tải lên: 07/07/2014, 04:20