... growth of the metastasis or the hormone-related symptoms are not controlled with endocrine therapy. Patients with high-grade neuroendocrine Chapter 095. Carcinoma of Unknown Primary (Part 5) ... noted, and 10–15% long-term survivors have been reported. Neuroendocrine Carcinoma Low-grade neuroendocrine carcinoma often has an indolent course, and treatment decisions...
Ngày tải lên: 07/07/2014, 04:20
... Chapter 095. Carcinoma of Unknown Primary (Part 2) Role of Imaging Studies Chest x-rays are always obtained in CUP workups but are often negative, especially ... 60% of CUPs are found to be adenocarcinoma, and 5% are squamous cell carcinoma. The remaining 30% of lesions are diagnosed as poorly differentiated adenocarcinoma, poorly differentiated carcinoma, ... n...
Ngày tải lên: 07/07/2014, 04:20
Chapter 095. Carcinoma of Unknown Primary (Part 3) pdf
... of CUP Tissue Marker Diagnosis Estrogen and progesterone receptors Breast cancer BRST-1 Breast cancer Gross cystic disease fibrous protein- 15 Breast cancer Chapter 095. Carcinoma of ... cystic disease fibrous protein- 15 Breast cancer Chapter 095. Carcinoma of Unknown Primary (Part 3) Role of Immunohistochemical Analysis Immunohistochemical stains are...
Ngày tải lên: 07/07/2014, 04:20
Chapter 095. Carcinoma of Unknown Primary (Part 4) ppt
... evaluating the role of molecular studies in CUP. Carcinoma of Unknown Primary: Treatment Chapter 095. Carcinoma of Unknown Primary (Part 4) There are 20 subtypes of cytokeratin (CK) intermediate ... a primary tumor of the colon; 75–95% of colon tumors show this pattern of staining. CK20–/CK7+ suggests cancer of the lung, breast, ovary, endometrium, an...
Ngày tải lên: 07/07/2014, 04:20
Chapter 095. Carcinoma of Unknown Primary (Part 6) pps
... Diagnostic strategies for unknown primary cancer. Cancer 100:1776, 2004 [PMID: 15112256] Bibliography Chapter 095. Carcinoma of Unknown Primary (Part 6) Management of Disseminated CUP Patients ... gemcitabine or irinotecan in carcinomas of unknown primary site: Results of a randomized phase II study—trial for the French Study Group on Carcinomas of Unk...
Ngày tải lên: 07/07/2014, 04:20
Chapter 095. Carcinoma of Unknown Primary (Part 1) pdf
... Chapter 095. Carcinoma of Unknown Primary (Part 1) Harrison's Internal Medicine > Chapter 95. Carcinoma of Unknown Primary Carcinoma of Unknown Primary: Introduction Carcinoma ... Carcinoma of unknown primary (CUP) is a biopsy-proven (mainly epithelial) malignancy for which the anatomic site of origin remains unidentified after an inten...
Ngày tải lên: 07/07/2014, 04:20
Chapter 019. Fever of Unknown Origin (Part 5) doc
... diagnosis of FUO. Chapter 019. Fever of Unknown Origin (Part 5) In any FUO workup, the erythrocyte sedimentation rate (ESR) should be determined. Striking elevation of the ESR and anemia of chronic ... polymyalgia rheumatica—common causes of FUO in patients >50 years of age. Still's disease is suggested by elevations of ESR, leukocytosis, and anemia and...
Ngày tải lên: 06/07/2014, 12:21
Chapter 019. Fever of Unknown Origin (Part 1) ppsx
... Causes (%) Chapter 019. Fever of Unknown Origin (Part 1) Harrison's Internal Medicine > Chapter 19. Fever of Unknown Origin Definition and Classification Fever of unknown origin ... the number of undetected cases of systemic lupus erythematosus and other autoimmune diseases. Table 19-1 Classic FUO in Adults A uthors (Year of Publicati Y ears of...
Ngày tải lên: 06/07/2014, 12:20
Chapter 083. Cancer of the Skin (Part 5) ppsx
... on"; range in color from flesh to tan, to dark brown. Chapter 083. Cancer of the Skin (Part 5) A lifetime risk of melanoma development of 6% has been estimated. The risk is greatest before ... Early detection of melanoma is difficult in these lesions because of the deep dermal or subcutaneous origin of primary melanoma and because of the large and varied su...
Ngày tải lên: 07/07/2014, 01:20
Chapter 005. Principles of Clinical Pharmacology (Part 5) doc
... site of action, it alters the function of that molecular target, with the ultimate result of a drug effect that the patient or physician can perceive. For drugs used in the urgent treatment of ... Pharmacology (Part 5) Adjusting Drug Dosages While elimination half-life determines the time required to achieve steady- state plasma concentrations (C ss ), the magnitude of...
Ngày tải lên: 06/07/2014, 08:20