carcinoma of unknown primary site
Chapter 095. Carcinoma of Unknown Primary (Part 2) pps
... 095. Carcinoma of Unknown Primary (Part 2) Role of Imaging Studies Chest x-rays are always obtained in CUP workups but are often negative, especially with low-volume disease. CT scans of ... to help find the primary, evaluate the extent of disease, and select the most favorable biopsy site. Older studies suggested that the primary tumor site is detected in 20–35% of patients who ... 60% of CUPs are found to be adenocarcinoma, and 5% are squamous cell carcinoma. The remaining 30% of lesions are diagnosed as poorly differentiated adenocarcinoma, poorly differentiated carcinoma, ...
Ngày tải lên: 07/07/2014, 04:20
báo cáo khoa học: " Classification of unknown primary tumors with a data-driven method based on a large microarray reference database" ppsx
Ngày tải lên: 11/08/2014, 12:21
báo cáo khoa học: "Primary myoepithelial carcinoma of palate" ppsx
Ngày tải lên: 09/08/2014, 02:21
Báo cáo khoa học: "Genomic alterations of primary tumor and blood in invasive ductal carcinoma of breast" pdf
Ngày tải lên: 09/08/2014, 03:21
Báo cáo y học: " Double primary bronchogenic carcinoma of the lung and papillary thyroid carcinoma: a case report" pps
Ngày tải lên: 11/08/2014, 21:22
Báo cáo y học: "Multivariate explanatory model for sporadic carcinoma of the colon in Dukes’ stages I and IIa"
... of that qualitative examination was the rejection of a total of 9 controls and 3 cases at the defining moment of the construction of the data package. The funda- mental cause was the lack of ... relationship between the appearance of spo- radic colorectal carcinoma (SCRC) and the diminution of the plasma cholesterol or some of its fractions, nor have different groups of patients (genetically ... “predisposing” for the condition with OR’s of 1.020 and 1.023 respectively and the rate of total cholesterol adopted an opposite direction with an OR of 0.986, all of them reaching statistical significance...
Ngày tải lên: 03/11/2012, 11:34
Tài liệu Restorative Techniques in Paediatric Dentistry: An Illustrated Guide to the Restoration of Carious Primary Teeth pptx
Ngày tải lên: 16/02/2014, 15:20
Tài liệu Báo cáo khoa học: Identification of critical active-site residues in angiotensin-converting enzyme-2 (ACE2) by site-directed mutagenesis docx
... effect of chloride ions on enzyme activity was investigated (Fig. 4). The hydrolysis of Mca- Fig. 3. Role of His505 and His345 in catalysis. Schematic of the proposed reaction intermediate of ACE2, ... altered and the CL2 site may be absent. Conclusion This study has highlighted the importance of Arg273 in binding of the C-terminus of peptide substrates by ACE2. The complete loss of activity observed ... nitrogen) of both residues are within hydrogen-bonding distance of the carbonyl oxygen of the amide group of residue P1Â (tACE) (Fig. 1B) or equivalent terminal carboxylate oxygen (ACE2) (Fig. 1A) of...
Ngày tải lên: 20/02/2014, 01:20
Tài liệu Báo cáo Y học: Identification of syntaxin-1A sites of phosphorylation by casein kinase I and casein kinase II ppt
... (1999) Phosphobase, a database of ph osphorylation sites: r elease 2.0. Nucleic A cids Res. 27, 237–239. 30. Aitken, A. & Learmonth, M.P. (1997) Analysis of Sites of Protein Phosphorylation. ... on phosphopeptides from each of the constructs. Because the site of phosphorylation by CKII was close to the N-terminus of syntaxin-1A, automated Edman degra- dation of the syntaxin ( 1–265) which ... ratio of 2 : 1 of the shorter form (Fig. 6). This Fig. 4. CKIa phosphorylates in vitro syntaxin 1 A on Thr21. Release of 32 P at each cycle of automatic Edman degradation after phosphory- lation of...
Ngày tải lên: 22/02/2014, 04:20
Báo cáo khoa học: Analysis of DNA-binding sites on Mhr1, a yeast mitochondrial ATP-independent homologous pairing protein potx
... DNA-binding activity of Mhr1 in the absence of Mg 2+ , because the DNA- binding activities of other HP proteins are often increased by the addition of Mg 2+ in vitro [31,32]. In the presence of 10 mm EDTA, ... changes of Mhr1 after ssDNA binding. (A) Schematic representa- tion of the positions of the Trp residues in Mhr1. (B) Emission spectra of wild-type Mhr1 (0.5 l M) with varying concentrations of the ... binding of Mhr1 to DNA by measuring changes in the fluorescence spectra of Mhr1 after binding. To distinguish the fluorescence of Trp from that of Tyr, we selected an excitation wavelength of 295...
Ngày tải lên: 06/03/2014, 09:22
Báo cáo khoa học: Semi-nested PCR analysis of unknown tags on serial analysis of gene expression potx
... analysis of unknown serial analysis of gene expression tags; rSAGE, reverse serial analysis of gene expression; SAGE, serial analysis of gene expression; TSAT-PCR, two-step analysis of unknown ... (CATG) sites were found between the site of the no. tag D tag and a poly(dA) among the cDNA of the gene (Hs. 436980). The blast results of another 11 sequences in the GenBank Table 1. Overview of ... course of our research on the SAGE data of the human spermatozoa, we became aware that other methods [rapid reverse transcription–PCR analy- sis of unknown SAGE tags (RAST-PCR) [15], genera- tion of...
Ngày tải lên: 07/03/2014, 04:20
Báo cáo khoa học: Identification of tyrosine-phosphorylation sites in the nuclear membrane protein emerin pot
... with a mass difference of 6 or multiples of 6. As a quarter of the reference Fig. 4. Identification of emerin and of tyro- sine-phosphorylation sites. (A) MS ⁄ MS spectrum of the mouse-emerin peptide DYNDD-pY-YEESYLTTK ... comparison of tyrosine-phosphorylated proteins Table 1. Phosphorylation sites of mouse and of human emerin. Phosphorylation site Number of phosphorylated residues Peptide sequence Residues Additional modifications ... pervanadate treatment of HeLa cells (20 large dishes) grown in the presence of the heavy amino acids 13 C 6 -arginine and 13 C 6 -lysine created a state of hyperphosphoryla- tion of all cellular proteins....
Ngày tải lên: 07/03/2014, 12:20
Báo cáo khoa học: Structure and function of N-acetylglucosamine kinase Identification of two active site cysteines pptx
... For determination of the K m of GlcNAc, different concentrations of GlcNAc were used in the presence of 10 m M ATP. For determination of the K m of ATP, different concentrations of ATP were used ... comparison of GlcNAc kinase with a model of the three-dimensional structure of glucokinase provides the first picture of the possible structure of the enzyme. Furthermore, two active site cysteines ... the identification of two active site cysteines of the sugar kinase by site- directed mutagenesis and computer-based structure prediction. Murine N-acetylglucosamine kinase contains six cysteine residues, all of...
Ngày tải lên: 08/03/2014, 10:20
Báo cáo khoa học: "Analysis of Unknown Words through Morphological Decomposition" potx
... analysis of words into morphemes based on user-defined rules. The basic system does not offer analysis of words containing unknown morphemes, nor does it provide a rank ordering of the output ... These points can multiply together and of- ten produce a large number of possible analyses. Out of the test set of 200 words, based on a lex- icon consisting of around 3500 morphemes (in- cluding ... rank ordered. A number of factors are exploited in the rank or- dering: - length of unknown root - structural ordering rules ([1, Ch. 3]) - frequency of affix Each of these factors will...
Ngày tải lên: 09/03/2014, 01:20