Chapter 095 Carcinoma of Unknown Primary (Part 4) ppt

... evaluating the role of molecular studies in CUP. Carcinoma of Unknown Primary: Treatment Chapter 095. Carcinoma of Unknown Primary (Part 4) There are 20 subtypes of cytokeratin (CK) intermediate ... a primary tumor of the colon; 75–95% of colon tumors show this pattern of staining. CK20–/CK7+ suggests cancer of the lung, breast, ovary, endometrium,...

Ngày tải lên: 07/07/2014, 04:20

... Chapter 095. Carcinoma of Unknown Primary (Part 2) Role of Imaging Studies Chest x-rays are always obtained in CUP workups but are often negative, especially ... 60% of CUPs are found to be adenocarcinoma, and 5% are squamous cell carcinoma. The remaining 30% of lesions are diagnosed as poorly differentiated adenocarcinoma, poorly differentiated carcinoma, ... n...

Ngày tải lên: 07/07/2014, 04:20

... of CUP Tissue Marker Diagnosis Estrogen and progesterone receptors Breast cancer BRST-1 Breast cancer Gross cystic disease fibrous protein- 15 Breast cancer Chapter 095. Carcinoma of ... cystic disease fibrous protein- 15 Breast cancer Chapter 095. Carcinoma of Unknown Primary (Part 3) Role of Immunohistochemical Analysis Immunohistochemical stains are...

Ngày tải lên: 07/07/2014, 04:20

... growth of the metastasis or the hormone-related symptoms are not controlled with endocrine therapy. Patients with high-grade neuroendocrine Chapter 095. Carcinoma of Unknown Primary (Part ... noted, and 10–15% long-term survivors have been reported. Neuroendocrine Carcinoma Low-grade neuroendocrine carcinoma often has an indolent course, and treatment decisions are b...

Ngày tải lên: 07/07/2014, 04:20

... Diagnostic strategies for unknown primary cancer. Cancer 100:1776, 2004 [PMID: 15112256] Bibliography Chapter 095. Carcinoma of Unknown Primary (Part 6) Management of Disseminated CUP Patients ... gemcitabine or irinotecan in carcinomas of unknown primary site: Results of a randomized phase II study—trial for the French Study Group on Carcinomas of Unk...

Ngày tải lên: 07/07/2014, 04:20

... Chapter 095. Carcinoma of Unknown Primary (Part 1) Harrison's Internal Medicine > Chapter 95. Carcinoma of Unknown Primary Carcinoma of Unknown Primary: Introduction Carcinoma ... Carcinoma of unknown primary (CUP) is a biopsy-proven (mainly epithelial) malignancy for which the anatomic site of origin remains unidentified after an inten...

Ngày tải lên: 07/07/2014, 04:20

... Figure 19-1 Chapter 019. Fever of Unknown Origin (Part 4) Specialized Diagnostic Studies Classic FUO A stepwise flow chart depicting the diagnostic workup and therapeutic management of FUO ... parasitic genera and species. The eventual clinical validation of such microarrays will further diminish rates of undiagnosed FUO of infectious etiology. tissue removed d...

Ngày tải lên: 06/07/2014, 12:21

... actual fever observed during 2–3 weeks of inpatient observation. Includes patients with exaggerated circadian rhythm. Chapter 019. Fever of Unknown Origin (Part 2) Infections, especially ... most frequent cause of FUO, giant-cell arteritis being the leading etiologic entity in this category. In patients >50 years of age, this disease accounts for 15–20% of FUO cas...

Ngày tải lên: 06/07/2014, 13:20

... many of which cause illnesses presenting with prolonged fever, underscores the need for obtaining an insightful environmental, occupational, and professional history, with early notification of ... history, with early notification of public health authorities in cases of suspicious etiology (Chap. 2 14). Table 19-3 Causes of FUO in Adults in the United States Infections Locali...

Ngày tải lên: 06/07/2014, 13:20

... Chapter 085. Neoplasms of the Lung (Part 4) Inherited Predisposition to Lung Cancer While an inherited predisposition ... Molecular Profiles Predict Survival and Response Just as the presence of EGFR TK domain mutations and amplification is an excellent predictor of response to EGFR TKIs, molecular predictors of response ... region 6q23 was found to segregate in familie...

Ngày tải lên: 07/07/2014, 01:20