Chapter 067 Applications of Stem Cell Biology in Clinical Medicine (Part 1) ppt
Chapter 067. Applications of Stem Cell Biology in Clinical Medicine (Part 1) ppt
... Chapter 067. Applications of Stem Cell Biology in Clinical Medicine (Part 1) Harrison's Internal Medicine > Chapter 67. Applications of Stem Cell Biology in Clinical Medicine Applications ... Applications of Stem Cell Biology in Clinical Medicine: Introduction Organ damage and the resultant inflammatory responses initiate a series of repair processes, including stem cell proliferation, ... types of stem cells include embryonic stem (ES) cells, umbilical cord blood stem cells, organ-specific somatic stem cells (e.g., neural stem cells for treatment of the brain), and somatic stem cells...
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Chapter 067. Applications of Stem Cell Biology in Clinical Medicine (Part 2) pps
... Chapter 067. Applications of Stem Cell Biology in Clinical Medicine (Part 2) Strategies for Stem Cell Replacement Stem cell transplantation is not a new concept and it is already part of ... concepts for cell replacement have been considered (Fig. 67 -1): (1) injection of stem cells directly into the damaged organ or into the circulation, allowing them to "home" into the damaged ... Strategies for transplantation of stem cells. 1. Undifferentiated or partially differentiated stem cells may be injected directly in the target organ or intravenously. 2. Stem cells may be differentiated...
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Chapter 067. Applications of Stem Cell Biology in Clinical Medicine (Part 3) pot
... development of dyskinesia. Transplantation of stem cell derived dopamine-producing cells offers a number of potential advantages over fetal transplants, including the ability of stem cells to ... Applications of Stem Cell Biology in Clinical Medicine (Part 3) Diabetes Mellitus The success of islet cell and pancreas transplantation provides proof of concept for a cell- based approach ... Transdifferentiation of bone marrow and adipose stem cells into neural stem cells, and vice versa, has been reported, and clinical trials of such cells have begun for a number of neurologic disorders. Clinical...
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Chapter 067. Applications of Stem Cell Biology in Clinical Medicine (Part 4) pot
... Essentials of Stem Cell Biology. San Diego, Elsevier Chapter 067. Applications of Stem Cell Biology in Clinical Medicine (Part 4) Other Organ Systems and the Future The use of stem cells in regenerative ... Biomedical Applications of Stem Cell Research et al: Stem Cells and the Future of Regenerative Medicine. Washington, D.C., National Academies Press, 2002 Holland S et al: The Human Embryonic Stem Cell ... Mimeault M et al: Stem cells: A revolution in therapeutics-recent advances in stem cell biology and their therapeutic applications in regenerative medicine and cancer therapies. Clin Pharmacol...
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Chapter 064. The Practice of Genetics in Clinical Medicine (Part 1) pptx
... Practice of Genetics in Clinical Medicine (Part 1) Harrison's Internal Medicine > Chapter 64. The Practice of Genetics in Clinical Medicine Implications of Molecular Genetics for Internal ... be seeing other specialists. The internist has an important role in educating patients about the indications, benefits, risks, and limitations of genetic testing in the management of Chapter ... concordance rate in monozygotic twins ranges between 50 and 90%. Diabetes or impaired glucose tolerance occurs in 40% of siblings and in 30% of the offspring of an affected individual. Despite the...
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Chapter 064. The Practice of Genetics in Clinical Medicine (Part 2) pptx
... or absence of nonhereditary risk factors among those affected with diseases, and the finding of multiple diseases in an individual patient. For instance, a woman with a history of both colon ... suggest an inherited disease, they should be extended to include additional family members. The determination of risk for an asymptomatic individual will vary depending on the size of the pedigree, ... two- to fivefold, underscoring the importance of family history for these prevalent disorders. Pending further advances in genetic testing, the key to assessing the inherited risk for common...
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Chapter 064. The Practice of Genetics in Clinical Medicine (Part 5) pptx
... Practice of Genetics in Clinical Medicine (Part 5) Molecular analysis is generally more informative if testing is initiated in a symptomatic family member, since the identification of a mutation ... disposition of test results. Informed consent should also include a discussion of the mechanics of testing. Most molecular testing for hereditary disease involves DNA-based analysis of peripheral ... child. In addition, there is concern that testing during childhood violates a child's right to make an informed decision regarding testing upon reaching adulthood. On the other hand, testing...
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Chapter 003. Decision-Making in Clinical Medicine (Part 1) doc
... Chapter 003. Decision-Making in Clinical Medicine (Part 1) Harrison's Internal Medicine > Chapter 3. Decision-Making in Clinical Medicine Decision-Making in Clinical Medicine: ... Uncertainty is compounded by the information overload that characterizes modern medicine. Today's experienced clinician needs close to 2 million pieces of information to practice medicine. ... Despite the great technological advances of medicine over the last century, uncertainty still plays a pivotal role in all aspects of medical decision-making. We may know that a patient does not...
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Chapter 003. Decision-Making in Clinical Medicine (Part 3) ppt
... underlying cause. The absence of a resting Chapter 003. Decision-Making in Clinical Medicine (Part 3) Diagnostic Hypothesis Generation Cognitive scientists studying the thought processes of ... focuses the attention of the examiner to the exclusion of all other inputs until answered, allowing the examiner to move on to the next specific question. Negative findings are often as important ... clinician who tries to be too efficient (as in the above example) can make serious errors. Use of a rapid systematic clinical survey of symptoms and organ systems can help prevent the clinician...
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Chapter 003. Decision-Making in Clinical Medicine (Part 5) pptx
... understanding of the patient's problem qualifies as a diagnostic test. Thus, even the history and physical examination can be considered a form of diagnostic test. In clinical medicine, it ... proportion of patients with disease who have a negative test is the false-negative rate and is calculated as 1 – sensitivity. The proportion of patients Chapter 003. Decision-Making in Clinical Medicine ... Medicine (Part 5) Economic Incentives Economic incentives are closely related to the other two categories of practice-modifying factors. Financial issues can exert both stimulatory and inhibitory...
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