applications of reflectance confocal microscopy in clinical dermatology

... strategies, a number of generic problems must be overcome for the development of successful clinical applications These include development of methods for reliably generating large numbers of specific ... specific cell types, minimizing the risk of tumor formation or proliferation of inappropriate cell types, ensuring the viability and function of the engrafted cells, overcoming immune rejection ... these differentiated cells integrate into organs, survive, and function after transplantation in vivo Early studies of bone marrow–derived stem cells transplanted into heart, liver, and other...

Ngày tải lên: 07/07/2014, 01:20

... (Fig 67-1): (1) injection of stem cells directly into the damaged organ or into the circulation, allowing them to "home" into the damaged tissue; (2) in vitro differentiation of stem cells followed ... variety of different cell types, including ES cells, bone marrow stem cells, endothelial stem cells, and adipose stem cells Bone marrow stem cells in particular have been examined in clinical ... employed intramyocardial, transendocardial, intravenous, and intracoronary injections In experimental myocardial infarction, functional improvements have been achieved after transplantation of a...

Ngày tải lên: 07/07/2014, 01:20

... the development of dyskinesia Transplantation of stem cell– derived dopamine-producing cells offers a number of potential advantages over fetal transplants, including the ability of stem cells ... facilitate remyelination after experimental spinal cord injury Clinical trials of marrow-derived stem cells have already begun, and this may be the first disease targeted for the clinical use of ES cells ... targeted for stem cell therapies include spinal cord injury, amyotrophic lateral sclerosis, stroke, traumatic brain injury, Batten disease, and Parkinson's disease In Parkinson's disease, the major...

Ngày tải lên: 07/07/2014, 01:20

... the use of federal funds for developing new human ES lines However, these existing lines develop abnormalities with time in culture and are contaminated with mouse proteins These findings have ... testing fundamental biology in the laboratory setting and in animal models before applying new techniques in carefully controlled clinical trials When these trials occur, they must include full informed ... applications in regenerative medicine and cancer therapies Clin Pharmacol Ther 82(3):252, 2007 [PMID: 17671448] National Institutes of Health: Stem cell information page URL: http://stemcells.nih.gov/index.asp...

Ngày tải lên: 07/07/2014, 01:20

... analyses in such a large sample The primary outcome of the study was a comparison of aspirin versus streptokinase for prevention of myocardial infarction, with a finding in favor of aspirin In subgroup ... “Since the investigator can describe only to a limited extent the kinds of participants in whom an intervention was evaluated, a leap of faith is always required when applying any study findings ... kind of measurement, such as points on a depression rating scale This measurement can be defined in various ways; for example, it can reflect the actual change in points on a depression rating...

Ngày tải lên: 01/11/2013, 11:20

... Interesting results are also obtained with the spline kernel (Figure 11a) and the degree B spline kernel (Figure 11b) The spline kernel offers an 300 Applications of Support Vector Machines in ... 24 patterns, 10 in class þ1 and 14 in class À1 In the learning (training) phase, the algorithm extracts classification rules using the information available in the learning set In the prediction ... the set of Lagrange multipliers of the training (calibration) patterns with li ! 0, and P in LP indicates the primal 312 Applications of Support Vector Machines in Chemistry formulation of the...

Ngày tải lên: 02/06/2014, 09:46

... of an in nite IFS containing affine transformations of l2 A ,” Proceedings of the American Mathematical Society, vol 136, no 2, pp 587–592, 2008 G Gwo´ d´ -Łukawska and J Jachymski, “The Hutchinson-Barnsley ... 2 Fixed Point Theory and Applications Let us mention some papers containing results on this direction Results concerning in nite iterated function systems have been obtained for the case ... chosen in K, we infer that fn → f on K, so u·c − fn −→ f 2.26 The inequality Lip f ≤ supn≥1 Lip fn is obvious From Lemma 2.11 and Proposition 2.12, using Proposition 2.7 ii we obtain the following...

Ngày tải lên: 21/06/2014, 23:20

... Medical Applications of Rapid Prototyping - A New Horizon Fig Segmentation using the software Fig Designing using CAD software Advanced Applications of Rapid Prototyping Technology in Modern Engineering ... Medical Applications of Rapid Prototyping - A New Horizon Fig Segmentation using the software Fig Designing using CAD software Advanced Applications of Rapid Prototyping Technology in Modern Engineering ... taught in medical schools 2 Advanced Applications of Rapid Prototyping Technology in Modern Engineering Steps in production of rapid prototyping models The various steps in production of an RP...

Ngày tải lên: 27/06/2014, 11:20

... phase lattice points can be arranged either in the form of grain inclusions, whiskers, 566 Applications of Monte Carlo Method in Science and Engineering fibers The influence of the input parameters ... second phase in the form of grains (5%) a), in the form of whiskers (5%) b), and in the form of fibers (10%) c) 2.3 Grain growth in two-phase materials When simulating grain growth in two-phase ... exponent in the kinetic equations, particularly in small grain size 582 Applications of Monte Carlo Method in Science and Engineering regimes (i.e., for grain sizes ranging from to 15 lattice spacing...

Ngày tải lên: 29/06/2014, 13:20

... 2011 Printed in India A free online edition of this book is available at www.intechopen.com Additional hard copies can be obtained from orders@intechweb.org Applications of Monte Carlo Method in ... and so forth In this book, Applications of Monte Carlo Method in Science and Engineering, we further expose the broad range of applications of Monte Carlo simulation in the fields of Quantum Physics, ... exited-state 10 Applications of Monte Carlo Method in Science and Engineering deactivation The energy level differences of some elements in a typical scintillator are in the range of some electronvolts...

Ngày tải lên: 29/06/2014, 13:20

... Printed in India A free online edition of this book is available at www.intechopen.com Additional hard copies can be obtained from orders@intechweb.org Applications of Monte Carlo Methods in ... interest rates Applications in business are the primary focus of this paper, but the kinds of structures set forth in this paper may also have potential applications in biological evolution in ... of the mathematical model underlying the simulation procedure Preface so that an investigator or team of investigators could write software in a programming language of their choosing so an interest...

Ngày tải lên: 29/06/2014, 13:20

... Medical applications of single-cell sequencing (a) Profiling of rare tumor cells in scarce clinical samples, such as fine-needle aspirates of breast lesions (b) Isolation and profiling of circulating ... detection using circulating tumor cells Another major clinical application of single-cell sequencing will be in the genomic profiling of copy number or sequence mutations in CTCs and disseminated ... through single-molecule sequencing, by requiring lower amounts of input DNA In summary, the future medical applications of singlecell sequencing will be in early detection, monitoring CTCs during...

Ngày tải lên: 11/08/2014, 12:21

... 2006, 34:1935-1940 Laver SR, Padkin A, Atalla A, Nolan JP: Therapeutic hypothermia after cardiac arrest: a survey of practice in intensive care units in the United Kingdom Anaesthesia 2006, 61:873-877 ... Implementing the International Liaison Committee on Resuscitation guidelines on hypothermia after cardiac arrest The German experience: still a long way to go? Crit Care 2006, 10:407 Page of (page...

Ngày tải lên: 13/08/2014, 03:20

... “speakers” of that language as if speaking includes all other kinds of knowing To define speaking Florez states that speaking is “an interactive process of constructing meaning that involves producing ... application of pair and groupwork in teaching and learning speaking skills (ii) to examine the current situations of the application of pair and group work in teaching and learning speaking skills ... activities in the classroom to increase and improve students‟ communicative competence I.1.3 Using CLT in teaching speaking skills According to CLT, teaching speaking skills involves the use of language...

Ngày tải lên: 28/03/2015, 09:41

... Tissue Engineering Applications 33 3.1 Introduction As explained in chapter 1, inadequate vascularization is a major bottleneck limiting widespread clinical applications of tissue engineering, and ... diabetic wounds 2.4 Potential applications of PHIs in tissue engineering As reviewed in chapter 1, clinical applications of engineered tissues are currently limited mainly to thin or avascular tissues ... repeated injections of PHIs into sites of implantation or injury is not feasible due to the associated pain, distress and risks of introducing infections We therefore propose the 34 incorporation of...

Ngày tải lên: 09/09/2015, 11:11

... 167 Chapter Introduction 1.1 Fuzzy logic Uncertainty exists in various aspects of life, resulting in an interesting world In the real world, uncertainties may arise from a variety of sources: ... Partition of the input space by Rule (green line), Rule (blue line) and the boundary between the two operating modes (red line) in 3.9 Ujmin when θ1 < θ2 57 Partition of the input ... uncertainties In order to improve the ability of fuzzy logic in handling complex uncertainties, type-2 fuzzy logic was introduced While the concept of type-2 fuzzy set was introduced by Zadeh in...

Ngày tải lên: 09/09/2015, 18:49

... prospect of using CMCS scaffolds as dentin remineralization patches in dentistry by assessing the mineralization inducing ability of the scaffolds in a tooth model, which represents a more clinically ... listed in Table 3.1 Adsorption of growth factor was carried out by immersing a pristine disc in 100 µl of loading solution containing µg/ml of BMP-2 or FGF-2 in PBS for h, followed by a rinsing ... or in combination with growth factors and bone marrow in bone grafting in the forms of solid or injectable cements depending on the indications of the bone defects to assist the regeneration of...

Ngày tải lên: 10/09/2015, 09:23

... Idea of AIM The basic idea of AIM is to approximate the far zone interaction using uniform grid points Since the Green’s function is translational invariant, the interaction between any two points ... central point integration for the testing functions, in this way, for each testing function, we have to interpolate the potentials at the associate grid points to the center of the testing function ... relative error of for matrix elements of Zmn using different grid sizes paper, we choose a grid size of 0.1λ0 since the accuracy of 1% relative error is good enough for most engineering applications...

Ngày tải lên: 11/09/2015, 09:16

... with an International Conference in Tissue Banking held in Berlin in 1991 The following year, in 25 ch03 FA March 15, 2007 22:5 26 b478 Radiation in Tissue Banking Trim Size: 9in x 6in A Nather, ... Department of Orthopaedic Surgery Yong Loo Lin School of Medicine National University of Singapore Singapore S.-H Neo NUH Tissue Bank Department of Orthopaedic Surgery Yong Loo Lin School of Medicine ... Radiation in Tissue Banking Trim Size: 9in x 6in This page intentionally left blank ch01 FA March 15, 2007 22:3 b478 Radiation in Tissue Banking Trim Size: 9in x 6in Chapter Types of Terminal Sterilization...

Ngày tải lên: 22/03/2014, 20:21

... adjusted by including/excluding weight plates like those used in strength training 6 Applications of EMG in Clinical and Sports Medicine Each participant performed two series of ten repetitions of the ... complaints of pain in other regions of the trunk A model that divides the spine into more segments, while not reflecting the total number of vertebrae in the spine, would bring the study of the internal ... Expressing the equations (31) and (28) in terms of Mi and yi resulted in the determination of the weights of the cubic spline ai, bi, ci and di 30 Applications of EMG in Clinical and Sports Medicine...

Ngày tải lên: 27/06/2014, 16:20