... discovered in BE and EAC, including frequent gain of chromosomes 6p (1 0–3 7%), 7q (1 7–3 7%), 7p (3 0–6 0%), 8q (5 0–8 0%), 10q (2 0–5 0%), 15q (1 0– 40%), 17q (3 0–5 0%), and 20q (5 0–8 0%); and frequent loss ... Komatsu and Michael K. Gibson Chapter 8 Nonsurgical Management of Esophageal Cancer 171 Malek M. Safa and Hassan K. Reda Esophageal Cancer – Cell and Molecular Biology, Biomarkers, Nutrition and ... chromosomes 4q (2 0–5 0%), 5q (2 0–5 0%), 9p (2 0–5 0%), 14q (3 0–4 0%), 16q (3 6–4 0%), 17p (30%), 18q (2 0–6 0%) and Y (6 0– 76%). The proto-oncogenes are often duplicated, such as MYC (8q), EGFR (7p) and ERBB2...