... replication in most organs, including the liver,spleen, and eventually the brain [284]. The disseminationof infection to the brain and the severity of infection of the peripheral organs depend in part ... of the host, it will be in both interests, including the virus,to settle the conflict amicably. Some important weapons of the unspecific defence and the early strikes and beginning battle during ... cycle of the virus. A little later, other cytokines such as IL-12, IL-18 and IFN-γ are produced and give rise to other weapons in the battle against the virus. They will, in turn, within the nextreplication...