... min (4 h) after which there was a decline (Fig. 4C,D), indicating enzyme stability in the pH range 2.0–5.0 and 45–60 °C in the initial hours. The effect of varying chitosan concentration on the ... The peak corresponding to -CH 3 showed a slight decrease in the height in case of LMWC further supporting a decrease in the DA [33] (Table 3 and Fig. 1). In LMWC, the...
Ngày tải lên: 19/02/2014, 12:20
... gel electrophoresis and the bands eluted, purified and subcloned in the PCRII TM TOPO vector containing the lac promoter and the b-galactosidase gene, using the TA Cloning Kit (Invitrogen, USA). Transformation ... c-guanidino group of the P1 Arg residue in the inhibitor and/ or substrate molecule [39]. Additional inter- actions in the interior of the extended sub...
Ngày tải lên: 17/03/2014, 09:20
Báo cáo khoa học: Pigment epithelium-derived factor binds to cell-surface F1-ATP synthase pdf
... neovascu- larization and tumorigenesis, and delays retinal cell death in vivo [4,8–18]. PEDF induces endothelial cell apoptosis, inhibits the proliferation and migration of endothelial cells, and blocks the formation ... assessed the binding of PEDF to endothelial cell- surface ATP synthase, and examined the effect of PEDF on the extracellular ATP synthesis ac...
Ngày tải lên: 22/03/2014, 21:21
Báo cáo khoa học: "Impact of computerized physician order entry on medication prescription errors in the intensive care unit: a controlled cross-sectional trial"
... the clinical pharmacist, comprising 1,286 in the C-U and 1,224 in the PB-U. In the C-U, 44 MPEs occurred versus 331 in the PB-U (3.4% versus 27.0%, P < 0.001). Overall, the ICIS resulted in ... 0.001). Conclusion The ICU computerization, including the medication order entry, resulted in a significant decrease in the occurrence and severity of medication...
Ngày tải lên: 25/10/2012, 10:39
Tài liệu Báo cáo khoa học: Fatty acid synthesis Role of active site histidines and lysine in Cys-His-His-type b-ketoacyl-acyl carrier protein synthases ppt
... proposed to inject the acyl chain into the sub- strate-binding pocket [32]. If a similar mechanism is involved in the KAS I reaction then an intermediate ACP-acyl–KAS I crystal complex remains to ... at the N e position (Fig. 1) and (b) a cation detected octahedrally co-ordinated in the vicinity of the active site (Fig. 2). Three of the six cation lig- ands are main-chain...
Ngày tải lên: 19/02/2014, 08:20
Tài liệu Báo cáo khoa học: "Discriminative Lexicon Adaptation for Improved Character Accuracy – A New Direction in Chinese Language Modeling" pptx
... beginning with only characters in the lexi- con and using the training data to alter the current lexicon in each iteration. This is also an interesting direction. References Maximilian Bisani and ... Mar. Pak-kwong Wong and Chorkin Chan. 1996. Chinese word segmentation based on maximum matching and word binding force. In Proceedings of the 16th International Conference o...
Ngày tải lên: 20/02/2014, 07:20
Báo cáo khoa học: Proteomic analysis reveals Hrs ubiquitin-interacting motif-mediated ubiquitin signaling in multiple cellular processes ppt
... and these cellular processes. Characterization of Munc18-1 and Hsc70 as Hrs UIM-interacting ubiquitinated proteins The ability of the Hrs UIM domain to bind ubiquitin and ubiquitinated proteins ... ubiquitin-protein ligase(s) and ⁄ or kinase(s). The identities of ubiquiti- nated cargo and other cellular proteins that are recog- nized by the Hrs UIM domain remain largely unkn...
Ngày tải lên: 07/03/2014, 03:20
Báo cáo Y học: Amphipathic property of free thiol group contributes to an increase in the catalytic efficiency of carboxypeptidase Y pot
... (Cys341) is involved in substrate binding at the S1 subsite and in maintaining the width and depth of the S1 subsite; (b) the rearrangement of the S1 subsite induced by the interaction between the SH group ... DG s is the binding energy of the substrate to the enzyme, DG à is the activation energy in the chemical steps of bond making and breaking, DG ‡ T is...
Ngày tải lên: 08/03/2014, 23:20
Báo cáo khoa học: Existence of novel b-1,2 linkage-containing side chain in the mannan of Candida lusitaniae, antigenically related to Candida albicans serotype A potx
... were identified as the one and three b-1,2 linkage-containing oligomannosyl side chains, LM4 and LM6, respectively. Therefore, the amount of the two b-1,2 linkage-containing Table 1. Chemical shifts of the ... 2003 the adherence of Candida cells to mammalian cells as the first step in infection [26–28]. Poulain and his coworkers [29–32] reported that the b-1,2 linkage-cont...
Ngày tải lên: 17/03/2014, 03:20
Báo cáo khoa học: "Using Leading Text for News Summaries: Evaluation Results and Implications for Commercial Summarization Applications" ppt
... passing. These customers generally can expect higher preci- sion and lower recall when they restrict their Boo- lean queries to the headline and leading text than if they were to apply their ... to the full text. Documents in our news database have several text fields including HEADLINE and BODY fields. Searchable LEAD software identifies the leading portion of the BOD...
Ngày tải lên: 17/03/2014, 07:20