Báo cáo khoa học: Characterization of the serotoninergic system in the C57BL/6 mouse skin potx

... have been identified in those strains that are responsible for most of the steps in the biosynthesis of the oligosaccharide portions of the LPS molecules. The inner core of H. in uenzae LPS has ... from the nasopharynx to the middle ear via the eustachian tube, often in the presence of viral respiratory infections [5]. Whether all colonizing strains of H....

Ngày tải lên: 16/03/2014, 16:20

... localize the ligand binding sites in the leukocyte b 2 integrins. The a chains of the CD11/CD18 integrins contain an inserted approxi- mately 200-amino-acid intervening domain (I domain), which ... anti-ICAM-4 antibodies, indicate a major role for ICAM-4 in binding of red cells to the I domains. The efficient inhibition of the Fig. 10. Specific binding of purified recom...

Ngày tải lên: 20/02/2014, 11:20

... Norway Haemerythrin proteins comprise a family of O 2 -carrry- ing proteins mainly found in a few phyla of marine invertebrates. Members of this family differ from haemoglobin and haemocyanin in that they ... from the PCR fragment amplified with the primers used in the cloning of MCA0715. The arrowhead indicates the 540 bp transcript, corresponding to the predicted le...

Ngày tải lên: 07/03/2014, 17:20

... favoured over lysine [4]). Specificity is primarily determined by interaction of the side chain of the C-terminal amino acid of the substrate with a binding pocket on the enzyme, with amino acid 255 (human ... majority, and by 20 min all, of the original 50 kDa protein had been digested, with an increase in staining of the bands of  36 kDa and  13 kDa. On further in...

Ngày tải lên: 23/03/2014, 12:20

... mutant proteins. This was interpreted as a lack of fosfomycin binding to these mutant proteins [12]. Binding of fosfomycin to either wild-type MurA or the K22 mutant proteins in the absence of UDPNAG is not ... of R120 by lysine reduces the probability of forming the fully closed form of the protein. The results obtained with the K22V/R120K double mutant protein po...

Ngày tải lên: 19/02/2014, 13:20

... cyanidin; 100 nm bilirubin and 100 nm biliverdin. Under the condi- tions of the assay, bilirubin is freely soluble in the buffer [58]. The presence of these inhibitors in the assay medium may interfere ... antibody A in the presence of increasing concentrations of bilirubin. BSP uptake was assayed to track the progress of the antibody-induced inhibition. Figure...

Ngày tải lên: 20/02/2014, 01:20

... by the C domain of the initiation module of dapto- mycin. That DptE and DptF are involved in the lipidation process of daptomycin was first shown by Miao et al. [1]. In their work, the daptomycin ... is GLDSV, indicating that this putative ACP domain is one of the few ACPs in which valine replaces isoleucine (I) or leucine (L) in the conserved sequence. To determine...

Ngày tải lên: 07/03/2014, 04:20

... carbonyl of Asn by the nitrogen of the peptide group linking the Asn to the following residue [4–6] 2 . As hydrolysis of this intermediate may occur on either side of the imide nitrogen, the Asp ... containing the regulatory and catalytic domains [15]. Fig. 2. Stereo picture of the three Asn residues in the N-terminal autoregulatory sequence of rPAH. Figure bas...

Ngày tải lên: 08/03/2014, 08:20

... of the MR151- derived strain with the crtIa deletion (MR841) com- pletely lose the red color typical of colonies from the parental strain, suggesting that the absence of CrtIa blocks the synthesis ... compilation ª 2007 FEBS 4307 in- frame deletion of crtIa in M. xanthus strain MR151. This strain contains a mutation, carR3, which renders the expression of the carB...

Ngày tải lên: 16/03/2014, 05:20

... are the pH and E h7 in the experiments with the addition of inhibitor (the arrow indicates the time of addition); curves (C) and (D) are the pH and E h7 in the control experiment. Thiol groups in ... addition of NEM or AMdiS to a reducing culture of L. lactis rapidly increased the E h7 and restored the initial E h7 value (Fig. 3). These data show the implicati...

Ngày tải lên: 22/03/2014, 21:21