Báo cáo khoa học: Calpain 1–titin interactions concentrate calpain 1 in the Z-band edges and in the N2-line region within the skeletal myofibril doc
... 2578–2590 ª 2005 FEBS Calpain 1 titin interactions concentrate calpain 1 in the Z-band edges and in the N2-line region within the skeletal myofibril Fabrice Raynaud 1 , Eric Fernandez 2 , Gerald Coulis 2 , ... Thus, according to these and previous results [20, 21] , titin appears to be a calpain carrier that concentrates cal- pain 1 and 3 in...
Ngày tải lên: 23/03/2014, 13:20
... 6 G155K, D (15 6 15 7), A158E 66 ± 12 73 ± 6* M149K, G155K, D (15 6 15 7), A158E 58 ± 5 15 6 ± 13 * N152D, G155K, D (15 6 15 7), A158E 62 ± 8 76 ± 7* M149K, N152D, G155K, D (15 6 15 7), A158E 93 ± 16 14 8 ± 17 * * Significantly ... this region, adapted from [2]. Residue 14 7 14 8 14 9 15 0 15 1 15 2 15 3 15 4 15 5 15 6 15 7 15 8 15 9 16 0 17 0 17 1 17 2 Consensus – G K...
Ngày tải lên: 20/02/2014, 11:20
... RNA–protein interactions in RNA folding FEBS Journal 278 (2 011 ) 16 34 16 42 ª 2 011 The Authors Journal compilation ª 2 011 FEBS 16 37 Tat peptide induced a change in the population of coexisting and interchanging ... http://wileyonlinelibrary.com/ onlineopen#OnlineOpen_Terms (Received 23 November 2 010 , revised 8 February 2 011 , accepted 11 March 2 011 ) doi :10 .11 11/ j...
Ngày tải lên: 14/02/2014, 19:20
Tài liệu Báo cáo khoa học: Rac upregulates tissue inhibitor of metalloproteinase-1 expression by redox-dependent activation of extracellular signal-regulated kinase signaling pptx
... Heath JK (19 92) Involvement of AP1 and PEA3 binding sites in the regulation of murine tissue inhibitor of metalloproteinases -1 (TIMP- 1) transcription. Biochim Biophys Acta 11 71, 41 55. 38 Ulisse ... & Narumiya S (19 96) Rhotekin, a new putative target for Rho bearing homology to a serine ⁄ threonine kinase, PKN, and rhophilin in the rho-binding domain. J Biol Chem 2 71,...
Ngày tải lên: 19/02/2014, 05:20
Tài liệu Báo cáo khoa học: Role of transcription factor activator protein 1 (AP1) in epidermal growth factor-mediated protection against apoptosis induced by a DNA-damaging agent doc
... 7.4, containing 13 5 mm NaCl) supple- mented with a mixture of protease inhibitors (10 0 lgÆmL )1 PMSF, 2 lgÆmL )1 leupeptin, 1 lgÆmL )1 pepstatin A, and 1 lgÆmL )1 p-toluenesulfonyl-l-arginine methyl ... for the PDGF and EGF receptor protein-tyrosine kinases in vivo and in vitro. Cell 57, 11 09 11 22. 18 Holgado-Madruga M, Emlet DR, Moscatello DK, Godwin AK & W...
Ngày tải lên: 19/02/2014, 06:20
Tài liệu Báo cáo khoa học: Three-dimensional structures of thermophilic b-1,4-xylanases from Chaetomium thermophilum and Nonomuraea flexuosa Comparison of twelve xylanases in relation to their thermal stability pdf
... (0.99) 17 7 (0.93) 19 6 (0.98) 19 2 (1. 01) 16 9 (0.93) 203 (0.98) 17 0 (0.94) 16 9 (0.93) main-main 11 6 (0.59) 11 8 (0.62) 12 1 (0. 61) 11 7 (0.60) 11 5 (0.59) 11 7 (0.60) 11 7 (0.62) 10 9 (0.59) 11 6 (0. 61) 10 8 ... 19 4 19 0 18 5 19 0 17 8 18 2 18 1 18 4 207 Hydrogen bonds 19 1 (1. 00) 17 9 (0.94) 200 (1. 01) 19 9 (1. 03) 19 6 (1. 01) 19 2 (0.99) 18 3 (0.96)...
Ngày tải lên: 20/02/2014, 23:20
Báo cáo khoa học: A Caenorhabditis elegans model of orotic aciduria reveals enlarged lysosome-related organelles in embryos lacking umps-1 function potx
... 5¢-TCA AAATTGGTGTGAATGACGAGAAAC-3¢ and P598. The resulting F11E6 .1: :mCherry product was coinjected into N2 at 20 ngÆlL )1 with pRF4[Rol-6 D ] at 10 0 ng ÆlL )1 . kxEx148 [F11E6 .1: :mCherry; rol-6(su1006) D ] was used in the ... pyr -1( RNAi) f 10 0 73 umps -1( RNAi); pyr -1( cu8) f 00 0 31 umps -1( zu456); pyr -1( cu8) m 00 0 40 umps -1( zu456); R12E2 .11 (RNAi) f 10 0 0 0...
Ngày tải lên: 06/03/2014, 09:22
Báo cáo khoa học: Post-ischemic brain damage: targeting PARP-1 within the ischemic neurovascular units as a realistic avenue to stroke treatment pptx
... regarding the molecular mechanisms underlying the detrimental role of the enzyme in ischemic brain injury [ 31, 32]. Indeed, although we know in part the mechanisms activated by PARP -1 and triggering neurotoxicity, ... Metab 19 , 819 –834. 17 Iadecola C & Alexander M (20 01) Cerebral ischemia and in ammation. Curr Opin Neurol 14 , 89–94. 18 Wang X & Feuerstein G...
Ngày tải lên: 07/03/2014, 03:20
Báo cáo khoa học: Activation of nematode G protein GOA-1 by the human muscarinic acetylcholine receptor M2 subtype Functional coupling of G-protein-coupled receptor and G protein originated from evolutionarily distant animals doc
... relatively low, the N-terminal region (aN–a1), the aF–aG region and the C-terminal region (a4–a5) were well conserved between GOA -1 and Ga o [ 31, 32]. The five regions of the Ga-subunit involved in receptor ... GTPcS in GOA -1. The IC 50 value of the displacement of GTPcS by GDP was 3 · 10 )6 m with 0.2 mm atropine, and 10 )4 m without atropine in the p...
Ngày tải lên: 07/03/2014, 11:20
Báo cáo khoa học: Leukocyte–endothelial cell interactions pot
... activation, resulting in a transfer of leukocyte integrins into a high affinity conformation. The integrins now allow the leukocytes to adhere firmly to the endothelium by interactions with intercellular adhesion ... small GTPases, reactive oxygen species and protein kinases, are involved in these signaling events. doi: 10 .11 11/ j .17 42-4658.2006.05436.x FEBS Journal 273 (2006...
Ngày tải lên: 07/03/2014, 12:20