ah woe is me
ah woe is me
... boarding school. They come home once a year at Christmas, and the first time the narrator meets the children, she is surprised at their well-mannered behaviour. She finds, however, that Sarah is a bit harsh ... this time. While she allows Sarah's children to stay in her house during Christmas, I think the only reason she does it is because she tries to escape her own bad conscience...
Ngày tải lên: 21/03/2014, 21:55
Tài liệu Báo cáo khoa học: Phosphorylation of cyclin dependent kinase 4 on tyrosine 17 is mediated by Src family kinases pptx
... phosphory- lation is independent of p27 KIP1 . The finding that Y17 phosphorylation is mediated by Src family kinases is completely novel and it is interesting to note how this fits in with the previously published ... D kinase is controlled could provide new therapeutic targets and strategies for the treatment of cancer. The activity of the CDK4 ⁄ cyclin D holoenzyme is regulated b...
Ngày tải lên: 18/02/2014, 18:20
Tài liệu Báo cáo khoa học: Staphylococcal enterotoxin C1-induced pyrogenic cytokine production in human peripheral blood mononuclear cells is mediated by NADPH oxidase and nuclear factor-kappa B doc
... Christian University, Tainan, Taiwan 2 Department of Microbiology and Immunology, Medical College, National Cheng Kung University, Tainan, Taiwan 3 Department of Medical Research, Chi-Mei Medical ... of staphylococcal enterotoxins causes emesis and diarrhea [4]. Staphylococcus aureus is also an important microorganism of bovine, ovine and caprine mastitis [5]. Staphylococcal enterotoxins, e...
Ngày tải lên: 19/02/2014, 00:20
Tài liệu Báo cáo khoa học: Aggregative organization enhances the DNA end-joining process that is mediated by DNA-dependent protein kinase pdf
... ligase 1 23456789101112131415 Multimer Trimer Dimer Monomer 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 DNA affinity fraction Multimer Trimer Dimer Monomer Mono Q fraction ATP + - + + + + + + + + + ++ ++ + + + + + ++ ++ + + + + Fig. ... nuclear matrix ⁄ scaffold attachment DNA elements. EMBO J 11, 3431–3440. 18 Krasnow MA & Cozzarelli NR (1982) Catenation of DNA rings by topoisome...
Ngày tải lên: 19/02/2014, 06:20
Báo cáo khoa học: Vanadium-induced apoptosis of HaCaT cells is mediated by c-fos and involves nuclear accumulation of clusterin pptx
... Clusterin-mediated apoptosis is regulated by adenomatous polyposis coli and is p21 dependent but p53 independent. Cancer Res 64, 7412–7419. 65 O’Sullivan J, Whyte L, Drake J & Tenniswood M (2003) ... apoptosis of HaCaT cells is mediated by c-fos and involves nuclear accumulation of clusterin Soultana Markopoulou 1, *, Evangelos Kontargiris 1, *, Christina Batsi 1, *, Theodore Tzavar...
Ngày tải lên: 16/03/2014, 02:20
Báo cáo khoa học: Transcriptional regulation of the desferrioxamine gene cluster of Streptomyces coelicolor is mediated by binding of DmdR1 to an iron box in the promoter of the desA gene doc
... ‘com- mitting’ enzymes for secondary metabolites that have evolved as variants of enzymes involved in primary metabolism [23]. All the evidence from this work indicates that the desABCD cluster is expressed ... Spain Iron is an essential element required for many key metabolic processes (including cytochrome and Fe-S electron transporters) in almost all micro-organisms. The bioavailabilit...
Ngày tải lên: 16/03/2014, 11:20
Báo cáo khoa học: Deadenylation of interferon-b mRNA is mediated by both the AU-rich element in the 3¢-untranslated region and an instability sequence in the coding region pot
... exosome [8]. This complex first discovered in yeast [9], is composed of proteins with ribonuclease activity and is able to direct 3¢)5¢ mRNA degradation. Therefore, the recruitment of the exosome ... with the Klenow polymerase before oligomerization. The DNA fragments were cloned in the T4 DNA polymerase blunted PstIsiteof the pSP65 vector. The length of the inserted fragments was estimate...
Ngày tải lên: 17/03/2014, 10:20
Báo cáo Y học: Induction of chicken ovalbumin upstream promoter-transcription factor I (COUP-TFI ) gene expression is mediated by ETS factor binding sites doc
... COUP-TFI and Ets-1: the mesenchyme of t he bladder ( Fig. 4A±D), the mesenchyme of the nasal septum (Fig. 4E±H), the cerebral cortex (Fig. 4I±L), the mesenchyme of vibrissae (Fig. 4M±P), spleen, ... 3D). Taken together, these experiments suggest that Ets-1 is able t o bind t he COUP-TFI promo ter preferentially at site C. This is not surprising because site C is the most closely related...
Ngày tải lên: 17/03/2014, 17:20
Báo cáo khoa học: Proteolysis of the tumour suppressor hDlg in response to osmotic stress is mediated by caspases and independent of phosphorylation pot
... (%) GAPDH hDlg 0361 Time after sorbitol treatment (h) 03 6 14 Time after UV treatment (h) 9 D hDlg protein level (%) 03691215 0 20 40 60 80 100 C Time after sorbitol release (h) Time after UV treatment (h) Fig. ... early stage of apoptosis or cell attachment. Our findings show that osmotic stress triggers hDlg degradation through a mechanism differ- ent from the one mediated by proteasomes, an...
Ngày tải lên: 23/03/2014, 06:20