The Neuronal Environment: Brain Homeostasis in Health and Disease pot

... types participate in the process of the control of the composition of the extracellular space in the brain: the cellular elements constituting intraparenchymal vessels, the endothelial cells lining the intraluminal ... number and volume of the CNS, the lymphatic drainage apparatus has been sacrificed, leaving the composition of extracellular fluids in the bra...

Ngày tải lên: 15/03/2014, 19:20

... seriously impaired. SYMPTOMS The earliest symptom is a dragging sensation in the back when the child is in the act of sucking, and an exhausted feeling of sinking and emptiness at the pit of the stomach afterwards. ... against, that of covering up the infant in its cot with too much clothing throwing over its face the muslin handkerchief and, last of all, drawing t...

Ngày tải lên: 23/03/2014, 02:20

... molecules, and 20 different amino acids are incorporated into protein during protein synthesis. Of the 20 amino acids in proteins, some are synthesized de novo in the body from either other amino acids ... fat, and protein. The amino acids in protein differ from the other two primary sources of dietary energy by inclusion of nitrogen (N) in their structures. Amino acids...

Ngày tải lên: 06/03/2014, 05:21

... capable to potentiate the effect of oxaliplatin in preventing the outgrowth of metastasis. Moreover, lunasin potentiated the effect of oxaliplatin in modifying expression of proteins involved in apoptosis ... resisting gastrointestinal and serum degradation, and reaching blood and target organs in an intact and active form. Efficacy of lunasin against breast, colon,...

Ngày tải lên: 23/03/2014, 04:20

... directly involved in ligand binding, presumably abolishing the interaction with signaling partners. The remaining mutations alter amino acids located outside the ligand-binding pocket and reduce ... lymphoproliferative dis- ease. Arginine 335 is found in the ‘BG loop’ not involved in phosphotyrosine binding and mutation to tryptophan most probably causes instability of the...

Ngày tải lên: 14/02/2014, 18:20

... with the EGF-binding domain [32]. The structural constraints of the EGFR binding region support a stochiometry of 1 : 1 for the decorin pro- tein core and EGFR, suggesting that decorin is bio- logically ... reduction in tumor growth [50]. Notably, decorin also interferes with cross-talk between the EGFR and the androgen receptor in pros- tate carcinoma cells [50]. The in...

Ngày tải lên: 15/03/2014, 23:20

... inactive zymogens, and a catalytic domain with a z inc-binding site (Zn, HEXXHXXGXXH) and a conserved methionine (Met-turn) supporting the catalytic zinc. Interaction between cysteine–zinc maintains proMMPs in ... (GAIP)-interacting C-terminus ⁄ synectin and calc ium ⁄ calmodulin-associated serine kinase, since the C2 region contains a class II PSD-95 ⁄ Discs-large ⁄ Zonula occlud...

Ngày tải lên: 15/03/2014, 23:20

... Gerling and Kerstin Heselmeyer-Haddad for their valuable input. Furthermore we gratefully acknowledge the intramural funding of the National Institutes of Health, the Karolinska Institutet, the ... ones, regardless of the actual ploidy status (i.e., the position of the stemline which is at 2c in the dGS and different from 2c in the aGS). In order to further e...

Ngày tải lên: 21/02/2014, 23:20

... 1996. Being black, living in the red: wealth andthecycleofracial inequal- ity. PhD thesis, Columbia Univ., New York 21. Corcoran M,DuncanGJ,Gurin G, Gurin P. 1985. Myth and reality: the causes and ... averages). Beyond measuring poverty in a more comprehensive way, there remain other thorny methodological issues in the child health and development literature. First and f...

Ngày tải lên: 14/03/2014, 11:20