... have been implicated in human in ammatory demyelinating neuropathies such asGuillain–Barre´syndrome and chronic in ammatorydemyelinating polyneuropathy [31]. In experimentalautoimmune neuritis, ... [5,7,22,23],mediates the rapid induction of cytokines and adhe-sion molecules that are implicated in immune and in ammatory responses [24,25]. Mitogen-activatedprotein kinases (MAPKs) are important mediatorsof ... 4347indicating that LPS induces ICAM-1 expression in SCs, suggest that ICAM-1 may play a role in the focalaccumulation and antigen-induced activation of T cells in inflammatory demyelinating diseases...