... a point of cross-talk between the autophagic and apoptotic pathways. Recently, a BH3 domain in the Bcl-2-binding domain of Beclin 1 was shown to bind to Bcl-X L [13]. Anti-apoptotic Bcl-2 and ... a link between the apoptotic and autophagic pathways through the interaction of the anti- apoptotic proteins Bcl-2 and Bcl-X L with Beclin 1. However, the nature of the interaction, either in ... from, apoptosis [9,10]. Beclin 1, a class III phosphatidylinositol 3-kinase- interacting protein [11], plays a role in promoting autophagy [12]. Beclin 1 contains a Bcl-2-binding domain which...
Ngày tải lên: 07/03/2014, 09:20
Ngày tải lên: 10/08/2014, 10:20
báo cáo khoa học: " Globalization and local response to epidemiological overlap in 21st century Ecuador" pdf
Ngày tải lên: 11/08/2014, 18:20
Tài liệu Biodiversity Response to Climate Change in the Middle Pleistocene ppt
... the indicator species used in the quantitative climate analysis 308 22.7. Highest temperature (summer) minima and lowest temperature (winter) maxima on the climate space shared by the indicator ... measured. As global warming continues into the coming decades, changes in biodiversity and other faunal dynamics will undoubtedly occur—indeed are probably already occurring (Schneider and Root, 1998; Post ... 100 years (Houghton et al., 2001). gestive tracts of carnivorans and raptors and were contained in fecal or regurgitation pellets before being dragged into the cave. In situations in which rocky...
Ngày tải lên: 17/02/2014, 20:20
Báo cáo khoa học: Cellular response to unfolded proteins in the endoplasmic reticulum of plants pptx
... chain is brefeldin A-insensitive and is inhibited by the proteasome inhibitor clasto-lactacystin b-lactone, resulting in the accumulation of ricin A chains. These stabilized ricin A chains are partly deglycosylated ... associates with a precursor of the storage protein glycinin in the ER, suggesting that the PDI-related protein participates in glycinin R. Urade Response to unfolded proteins in ER of plants FEBS Journal ... there are differences in the molecular mechanisms underlying the UPR between organisms. In yeast, the UPR increases the folding and degrada- tion capacities of unfolded proteins by inducing the expression...
Ngày tải lên: 16/03/2014, 11:20
Antibody response to influenza vaccination in the elderly: A quantitative review doc
... further gain insights into the impact of age and vaccine response. We controlled for every factor for which we could obtain data that may have had an impact on vaccineresponse, including living ... G, Barantceva I, Bichurina M, et al. The humoral response to live and inactivated in uenza vaccines administered alone and in combination to young adults and elderly. J Clin Virol 2002;24(3):193–201. [39] ... age-related changes in the cellular response and the acti- vationof theinnate immunesystem. Althoughthe underlying mechanism of T-cell responses to in uenza infection is not fully understood they are clearly...
Ngày tải lên: 28/03/2014, 20:20
Physiological and biochemical responses to salt stress in the mangrove pptx
... salinity, water stress, stomatal closure, decrease in intracellular CO 2 , and decrease in photosynthesis. The linear relation between photosyn- thesis and transpiration rates, the latter being ... in the presence of xanthineoxidase. A steep increase in the activity of SOD began immediately following the transfer of the plant grown in water into a 500mM NaCl solution (Fig. 5). The SOD and ... modified method of Elstner and Heupel (1976) and Ganschow and Schike (1969), respectively, and these results were then normalized to total protein in the sample. To investigate the effect of salt on...
Ngày tải lên: 06/07/2014, 02:20
Báo cáo khoa học: " Predicting a low cortisol response to adrenocorticotrophic hormone in the critically ill: a retrospective cohort study" pdf
Ngày tải lên: 13/08/2014, 03:21
LONDON AND PARIS AS INTERNATIONAL FINANCIAL CENTRES IN THE TWENTIETH CENTURY pot
... single player in the London money and capital markets. This was especially the case in the period leading up to the return of sterling to the gold standard in 1925, at the pre-war parity to the ... blamed on the latter. In particular, there appeared to be a link between the level and nature of the funding available for manufacturing industry in Britain after 1945 and either the lack of interest ... innovation in the provision of finance and the lack of constructive links between the City and industry as factors in the problems of British industry after 1945. 59 Nevertheless, the City continues to...
Ngày tải lên: 29/06/2014, 00:20
womens relations in the 19th century outline form
... surrounding their daily lives together, many of the women would not have survived the hardships that often presented themselves in life. Point of Analysis: I feel that the author was a bit long winded ... helped me to understand the women during this time much more. To see their lives on a much more personal level, and how they socialized really creates a deeper and more personal understanding of ... men did all day and if they had relationships like this with their friends and male kin. It is a great essay and does show vividly the lives of women during this timePoint of Synthesis: This article...
Ngày tải lên: 02/04/2014, 17:59
Báo cáo Y học: Nuclear proteins that bind to metal response element a (MREa) in the Wilson disease gene promoter are Ku autoantigens and the Ku-80 subunit is necessary for basal transcription of the WD gene ppt
... will also be of interest to examine whether additional proteins bind to the other three MREs in the WD promoter, and if so, to determine the precise mechanisms by which such proteins modulate WD ... a Ku-80 IR gene into cells inhibited the expression of the Ku-80 protein and the WD protein (Fig. 6B and C). In addition, the concurrent decrease in the level of Ku-70 from 0.5 to 12 h after transfection ... found to be highly homologous to the Ku proteins. Immunoblot analysis and EMSAs showed that the MREa-binding proteins are immunologically rela- ted to the Ku proteins. To study further the functional significance...
Ngày tải lên: 17/03/2014, 23:20
báo cáo hóa học: " Increased circulating leukocyte numbers and altered macrophage phenotype correlate with the altered immune response to brain injury in metallothionein (MT) -I/II null mutant mice" doc
... as immunoglobulin production [9-14]. Leukocytes infiltrate the injured CNS and have the potential to be neurotoxic which makes it difficult to determine if the increased cell death observe d in the injured ... expression in wild type and MT-I/II mice Plasma concentrations of Th1 and Th2 cytokines were assayed to determine if there were systemic differences in the inflammatory response to brain injury. Unfortu- nately ... follow- ing brain injury was also conducted to determine if the altered immune response to injury in MT-I/II -/- mice occurs before the cells enter the injured brain. Levels of the mRNA marker...
Ngày tải lên: 19/06/2014, 22:20
Báo cáo y học: "Synergistic role of c-Myc and ERK1/2 in the mitogenic response to TGF-1 in cultured rat nucleus pulposus cells" ppsx
Ngày tải lên: 09/08/2014, 01:22
báo cáo khoa học: " The Chinese government’s response to drug use and HIV/AIDS: A review of policies and programs" potx
Ngày tải lên: 11/08/2014, 18:20
Báo cáo y học: "Phenotypic and transcriptional response to selection for alcohol sensitivity in Drosophila melanogaste" ppt
Ngày tải lên: 14/08/2014, 08:20
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