Báo cáo khoa học: The chaperone and potential mannan-binding

Báo cáo khoa học: Protein aggregation and amyloid ﬁbril formation prediction software from primary sequence: towards controlling the formation of bacterial inclusion bodies pot

... Trovato et al. [21] looked for regions with the ability to pair with each other and form b-sheets, with their program termed pasta. The formation of b-strands is not the only predictor though. ... complex. The ability to form b-strands is a predominant feature in most works, either in the form of statistical propensities or in the form of structural stability. Yoon an...

Ngày tải lên : 06/03/2014, 00:20

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Báo cáo khoa học: Puriﬁcation and characterization of zebraﬁsh hatching enzyme – an evolutionary aspect of the mechanism of egg envelope digestion pot

... further incubation (60 min), the 39 kDa band disappeared, and only two bands with the same mobility as the 43 and 36.5 kDa products were detected (Fig. 5, lane 3). These results indicate that the ... from Asp48 and Val67 deduced from ZP2 cDNA, respectively. There- fore, the cleaving sites are Ser47 ⁄ Asp48 and Arg66 ⁄ Val67 (Fig. 6, sites A and B). The molecular masses...

Ngày tải lên : 07/03/2014, 04:20

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Tài liệu Báo cáo khoa học: Complex transcriptional and translational regulation of iPLA2c resulting in multiple gene products containing dual competing sites for mitochondrial or peroxisomal localization docx

... ites with a high match to chicken homeobox CdxA binding sites. Oligonucleotide g177 shares homology with the Oct1 binding site, whereas oligonucleotide g230 did not contain a predicted site for binding ... sequence (Fig. 5). The ﬁrst potential in-frame AUG start site occurs in exon 5 , while the nucleotide binding and lipase consensus sites occur in exons 7 and...

Ngày tải lên : 19/02/2014, 16:20

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Báo cáo khoa học: A zinc ﬁnger HIT domain-containing protein, ZNHIT-1, interacts with orphan nuclear hormone receptor Rev-erbb and removes Rev-erbb-induced inhibition of apoCIII transcription potx

... factor for coronary artery disease and atherosclerosis [21,22]. Therefore, a better understanding of the regulation of the expression of the apoCIII gene is of major importance for the treatment ... Rev-erbb (Fig. 7B). The function of ZNHIT-1 was dependent on the presence of the FxxLL motif for binding to Rev-erbb through its interaction with LBD (Fig. 5), and...

Ngày tải lên : 07/03/2014, 05:20

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Tài liệu Báo cáo khoa học: A knowledge-based potential function predicts the speciﬁcity and relative binding energy of RNA-binding proteins ppt

... interact with the protein [54], yet the disruption of the helix clearly affects the binding energy. The effect of these changes in RNA conformation cannot be captured by the intermolecular potential ... We anticipate that the performance of the potential will only increase with the size of the structural database and as terms are added to the model to account...

Ngày tải lên : 18/02/2014, 16:20

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Tài liệu Báo cáo khoa học: Membrane targeting and pore formation by the type III secretion system translocon pdf

... indirectly associated with the target membrane; rather, it assembles into a distinct structure at the tip of the T3SS needle, and potentially plays the role of assembly platform for the two hydrophobic ... at the tip of the secretion needle and its importance in the formation of the translocon strongly suggests that the hydrophilic translocator could be considere...

Ngày tải lên : 14/02/2014, 22:20

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Tài liệu Báo cáo khoa học: Identiﬁcation and characterization of the transcription factors involved in T-cell development, t-bet, stat6 and foxp3, within the zebraﬁsh, Danio rerio docx

... STAT protein DNA -binding domain and SH2 domain of stat6, and the zinc-ﬁnger domain, leucine-zipper domain and fork-head domain of foxp3. In addition, for stat6 and foxp3, there were a few other conserved features. ... sequences for human OSBPL7 and PPP1R3F, known to be located close to the T-bet gene and the Foxp3 gene, respectively, in the human genome. The human...

Ngày tải lên : 16/02/2014, 09:20

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Tài liệu Báo cáo khoa học: Neuropeptide Y and osteoblast differentiation – the balance between the neuro-osteogenic network and local control ppt

... Y2, Y4, Y5 and y6) that vary in their binding proﬁles and in their distribution in the central nervous system and periphery. Y1, Y2 and Y5 are the best characterized NPY receptors, and the majority ... resorption at multiple discrete sites; the osteoblasts, which are responsible for the synthesis and mineralization of bone matrix, forming new bone following resorptio...

Ngày tải lên : 18/02/2014, 04:20

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Tài liệu Báo cáo khoa học: Cobalamin uptake and reactivation occurs through speciﬁc protein interactions in the methionine synthase–methionine synthase reductase complex docx

... inset). The absorption spectrum of the puriﬁed enzyme was typical of the hydroxycobalamin form of the enzyme (Fig. 2). The recovery of the activity was  10%, and the enzyme was puriﬁed 3669-fold. The ... 0.01 With MSR 0.91 ± 0.14 With FMN domain 0.75 ± 0.02 With NADPH and MSR 1.12 ± 0.04 With NADPH and CPR 0.09 ± 0.02 With NADPH and nNOSred 0.18 ± 0.02 MeCbl...

Ngày tải lên : 18/02/2014, 08:20

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Tài liệu Báo cáo khoa học: Restricted localization of proline-rich membrane anchor (PRiMA) of globular form acetylcholinesterase at the neuromuscular junctions – contribution and expression from motor neurons doc

... form, the AChE G 1 and G 4 forms were predominant in embryonic muscles (Fig. 2D). In mature muscles, the relative proportion of the G 1 and G 4 forms was reduced and the asymmetric form of AChE (A 12 ) ... was consistent with an increase in total AChE activity (Fig. 5C) and with the observa- tion that G 4 was the predominant form of the enzyme in the adult spinal c...

Ngày tải lên : 18/02/2014, 08:20

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Báo cáo khoa học: The chaperone and potential mannan-binding lectin (MBL) co-receptor calreticulin interacts with MBL through the binding site for MBL-associated serine proteases pdf

Báo cáo khoa học: Protein aggregation and amyloid ﬁbril formation prediction software from primary sequence: towards controlling the formation of bacterial inclusion bodies pot

Báo cáo khoa học: Puriﬁcation and characterization of zebraﬁsh hatching enzyme – an evolutionary aspect of the mechanism of egg envelope digestion pot