... courses and effects of unlabeled ligands and low pH on the dissociation rates of [ 125 I]TC-PCSK9 (A) and [ 125 I]TC-PCSK9-D374Y (B) from HepG2 cells. Binding to equilibrium and removal of unbound ... of lipo- proteins, and there was a corresponding increase in the binding of [ 125 I]TC-PCSK9 and [ 125 I]TC-PCSK9- D374Y. Second, the extent of specific binding of both...
Ngày tải lên: 14/02/2014, 14:20
... expression of T-bet has been seen within a wide variety of tissues and cells in the Ginbuna crucian carp [27] and, in mammals, in the lung tissue of mouse and spleen and thymus of human and mouse ... the expression of these genes within humans and mice, of T-bet within Ginbuna crucian carp [27] and STAT6 in mandarin fish [28] have shown similar widespread expression. I...
Ngày tải lên: 16/02/2014, 09:20
Tài liệu Báo cáo khoa học: Molecular cloning and characterization of soybean protein disulfide isomerase family proteins with nonclassic active center motifs pdf
... stage of embryogenesis. Therefore, we next measured the mRNA and protein levels of GmP- DIL-3a and GmPDIL-3b by real-time RT-PCR and western blotting, respectively, during different stages of development. ... orthologs of other plants. Fig. S3. Expression and CD analysis of recombinant GmPDIL-3a and GmPDIL-3b. Table S1. List of primers for ATG-mutagenesis of GmPDIL-3a...
Ngày tải lên: 18/02/2014, 11:20
Tài liệu Báo cáo khoa học: SREBPs: physiology and pathophysiology of the SREBP family ppt
... physiology and pathophysiology of the SREBP family Hitoshi Shimano Department of Internal Medicine (Endocrinoglogy and Metabolism), Graduate School of Comprehensive Human Sciences, University of Tsukuba, ... conditions of overnutrition, SREBP-1c expression is elevated, and consequently, the levels of nuclear SREBP-1c protein and lipogenesis are enhanced in the liver and...
Ngày tải lên: 18/02/2014, 13:20
Tài liệu Báo cáo khoa học: Identification and characterization of an R-Smad ortholog (SmSmad1B) from Schistosoma mansoni pdf
... properties of SmSmad1 and SmSmad1B as described above. However, in the presence of SmSmad4 and the active mutant form of TbRI, both SmSmad2 and SmSmad4 interacted with GCN5, indicating the formation of ... Drosophila MAD and the vertebrate Smad1, Fig. 1. Structure of the SmSmad1B gene, cDNA and protein. (A) Schematic representations of the SmSmad1B gene, cDNA and prote...
Ngày tải lên: 18/02/2014, 16:20
Tài liệu Báo cáo khoa học: Topology, tinkering and evolution of the human transcription factor network doc
... cut-off k c . By using this algorithm, both hubs and connectors among hubs are retained. Acknowledgements Thanks to Dr J. Aldana-Montes and members of Kha- os group research of the University of ... Parisi D (2004) Defining and identifying communities in net- works. Proc Natl Acad Sci USA 101, 2658–2663. 67 Newman M (2002) Random graphs as models of net- works. Handbook of Grap...
Ngày tải lên: 19/02/2014, 07:20
Tài liệu Báo cáo khoa học: Antifungal effects and mechanism of action of viscotoxin A3 docx
... >, of (––) DPH and (ÆÆÆÆ) TMA-DPH incorporated into spores of F. solani in the absence of VtA 3 (n) and in the presence of 1.5 l M VtA 3 (s )and3 lM VtA 3 (n). Insert in (B) shows the evolution of ... potential and volume homeostasis of mitochondria. Cell 91, 627–637. 27 Haugland RP (1996) Handbook of Fluorescent Probes and Research Chemicals, 6th edn. Molecular Probe...
Ngày tải lên: 19/02/2014, 07:20
Tài liệu Báo cáo khoa học: Template requirements and binding of hepatitis C virus NS5B polymerase during in vitro RNA synthesis from the 3¢-end of virus minus-strand RNA docx
... deletion mutants of the 3¢ terminus of the minus-strand RNA but deletions were made on the basis of the structure of the 5¢UTR of the plus-RNA, the structure of the 3¢-end of the minus- strand RNA being ... this report, we investigated the template and binding properties of mutated and deleted RNA fragments of the 3¢-end of the minus-strand HCV RNA in the presence of...
Ngày tải lên: 20/02/2014, 01:20
Tài liệu Báo cáo khoa học: Purification and characterization of glutamate N-acetyltransferase involved in citrulline accumulation in wild watermelon doc
... & Kwon YM (2001) cDNA cloning of two isoforms of ornithine carbamoyltransferase from Canavalia lineata leaves and the effect of site-directed mutagenesis of the carbamoyl phosphate binding ... plants, acting as mediators of osmotic adjustment, stabilizers of subcellular structures, and scavengers of active oxygen radicals [4]. The mecha- nisms of proline, mannitol, an...
Ngày tải lên: 20/02/2014, 03:20
Tài liệu Báo cáo khoa học: "Online Large-Margin Training of Dependency Parsers" docx
... between a child and its parent. These features take the form of a POS trigram: the POS of the parent, of the child, and of a word in between, for all words linearly between the parent and the child. ... possible. Our system assumes POS tags as input and uses the tagger of Ratnaparkhi (1996) to provide tags for the development and evaluation sets. Table 2 shows the performa...
Ngày tải lên: 20/02/2014, 15:20