Tài liệu Báo cáo khoa học: Modulation of cyclin D1 and early growth response factor-1 gene expression in interleukin-1b-treated rat smooth muscle cells by n-6 and n-3 polyunsaturated fatty acids pdf

... action of EPA and DHA (Eur. J. Biochem. 271) 4473 Modulation of cyclin D1 and early growth response factor-1 gene expression in interleukin-1b-treated rat smooth muscle cells by n-6 and n-3 polyunsaturated ... [28]. Interestingly, the activity of the cyclin Fig. 3. In uence of n-3 polyunsaturated fatty acids (PUFAs) on cyclin D...

Ngày tải lên: 19/02/2014, 16:20

... line), in the presence of 100 l M neurotoxin ( • , dotted line), in the presence of 200 l M neurotoxin ( , dotted line) and in the presence of neurotoxin and 50 l M dopamine (h, dashed line). Modulation ... occur in the brain include selective loss of dopaminergic neurons in substantia nigra pars compacta and appearance of Lewy bodies consisting of aggregated pro...

Ngày tải lên: 14/02/2014, 19:20

... mediated by a relief of inhibition by cyclophilin D was evident in the form of slightly increased respiration rates during arsenolysis. However, the modulation of F 0 F 1 -ATP synthase by cyclophilin ... significant production of P i in the vicinity of the ATPase within the matrix. CYPD ablation or its inhibition by cyclosporin A increases the rate of respiration stim...

Ngày tải lên: 14/02/2014, 19:20

... mating and filamentous growth was normal in cells lacking ARE1 and ARE2 (data not shown), but apical bud growth following G 1 cyclin overexpression was affected (Fig. 5). During budding, the cyclin- dependent ... lacking histi- dine, leucine and uracil to monitor protein interactions. The unre- lated genes STE14 and UBC6 served as negative controls. Sterol homeostasis modul...

Ngày tải lên: 18/02/2014, 13:20

... efficiency, modulating the interaction of Y308 and ⁄ or the nicotin- amide with the isoalloxazine. This type of modulation of aromatic residue interactions could be a general strategy occurring in enzyme ... (2004) Role of the C-terminal tyrosine of ferredoxin-nicotinamide adenine dinucleotide phosphate reductase in the electron transfer processes with its protein partners fe...

Ngày tải lên: 18/02/2014, 17:20

... that the addition of ornithine or arginine to the culture medium cannot support the continuous growth of T. cruzi in the defined medium, as proliferation in the presence of these amino acids is arrested ... con- taining DNA spots (5 lg each) corresponding to inter- nal fragments of ADC or cruzipain genes. The latter (used as a control) is a housekeeping gene that encodes the...

Ngày tải lên: 19/02/2014, 07:20

... the investigation of b-cate- nin signalling [29]. In support of this aspect, using Madin–Darby canine kidney cells that express E-cadherin and b-catenin without any mutations, it was demonstrated ... protein into host target cells. This is achieved by a number of T4SS proteins, including CagI, CagL, CagY and CagA, which by itself binds the host cell integrin member b 1 foll...

Ngày tải lên: 14/02/2014, 19:20

... accumulation of oxidative stress in various ubiquinone-deficient strains and in the cyc1 mutant by measuring mRNA levels of stress-inducible genes and the phosphorylation level of the Spc1 MAP kinase. Induction ... Eugene, OR, USA). Cells were suspended in 10 mm Hepes (pH 7.4) containing 5% glucose and MitoTracker Red FM at a final concentration of 100 nm. After 15 min...

Ngày tải lên: 18/02/2014, 14:20

... Kharbanda S & Kufe D (1996) Interaction of cyclin- dependent kinase 2 and the Lyn tyrosine kinase in cells treated with 1-beta-D-arabinofuranosylcytosine. Oncogene 13, 939–946. 33 Bockstaele ... ME & Sherr CJ (1993) Direct binding of cyclin D to the retinoblas- toma gene product (pRb) and pRb phosphorylation by the cyclin D-dependent kinase CDK4. Genes Dev 7, 331–...

Ngày tải lên: 18/02/2014, 18:20

... Tanner [18]. Treatment of PhyAsr with 100 lm H 2 O 2 resulted in 33% of the enzyme being inactivated after 10 min of treatment and 65% being inactivated after 30 min. Incubation of the enzyme for up ... PTP1B [12,13] and RPTPa [15], the posi- tions of the active site arginine and the WPD loop are in the open (general acid) conformation. The general acid loop and active s...

Ngày tải lên: 18/02/2014, 18:20