EJ姶愛PI"6: K蔭T LU一N
Trong lu壱p"x<p"p {."o瓜v"j逢噂ng ti院p c壱n m噂k"8吋 t鰻ng h嬰p khung indazol-3-one thông qua ph違n 泳ng ho衣t hóa tr詠c ti院p liên k院t C(sp2)-H, s穎 d映pi"z¿e"vƒe"8欝ng và nhóm
8鵜pj"j逢噂ng 2-methylthioaniline cho ph違n 泳ng amine hóa k院t h嬰r"8„pi"x”pi"p瓜i phân t穎8«"8逢嬰c th詠c hi羽n. Vi羽c s穎 d映pi"pj„o"8鵜pj"j逢噂pi"ogvj{nvjkq"8吋 ho衣t hóa liên k院t C&J"vt‒p"x”pi"vj挨o"n "o瓜v"j逢噂ng nghiên c泳u khá m噂i, do ligand hai càng N,S- v"8逢嬰c s穎 d映ng ph鰻 bi院n trong t鰻ng h嬰p h英w"e挨0"D‒p"e衣pj"8„."ogvj{nvjkq"8逢嬰c bi院v"8院n là nhóm
8鵜pj"j逢噂ng có c医u trúc nh臼 g丑n và quy trình t鰻ng h嬰r"8挨p"ik違n. Ngoài ra, cpknkpg"8逢嬰c s穎 d映pi"n o"vƒe"pj¤p"cokpg"j„c"e pi"n "o瓜v"8k吋m m噂i c栄c"rj逢挨pi"rjƒr"p {."d荏i vì tính
8院n th運k"8k吋m hi羽n t衣i các nghiên c泳u hình thành liên k院t C(sp2)-P"8隠u ch雨 phù h嬰p v噂i các amine no b壱c 2, azide ho員e"cokpg"vj挨o"ej泳c"eƒe"pj„o"t¿v"8k羽n t穎0"Ak吋o"8員c bi羽t c栄a nghiên c泳u này là t鰻ng h嬰p khung ch医t indazol-3-one thông qua ph違n 泳pi"8„pi"
vòng n瓜i phân t穎, v嘘n ej逢c"v瑛pi"8逢嬰c công b嘘 vt逢噂e"8¤{0"Pj英ng nghiên c泳w"vt逢噂c
vj逢運ng s穎 d映ng các d磯n xu医t c栄a phenylbenzamide v噂i nhóm amino 荏 v鵜 trí ortho 8吋
th詠c hi羽n ph違n 泳ng amine hóa t衣o khung ch医t indazol-3-one. Fq"8„."pijk‒p"e泳w"p {"8«"
thành công trong vi羽c m荏 r瓜ng ph衣m vi 泳ng d映ng c栄c" pj„o" 8鵜pj" j逢噂ng 2- methylthioaniline e pi"pj逢"xk羽c s穎 d映ng tác nhân amine hóa không ph鰻 bi院n là aniline
8吋 hình thành khung indazol-3-one.
Trong th運i gian s逸p t噂i, ph違n 泳ng cokpg"j„c"8«"8逢嬰c trình bày trong lu壱p"x<p"p {"
s胤 ti院p t映c 8逢嬰c nghiên c泳w"u¤w"j挨p"8吋zƒe"8鵜pj"e挨"ej院."vtqpi"8„"m院t h嬰p m瓜t s嘘 k院t qu違 j„c"v pj"vqƒp"8吋 gi違k"vj ej"e挨"ej院 ho衣v"8瓜ng c栄c"pj„o"8鵜pj"j逢噂ng 2-methylthioaniline. Ngoài ra, m荏 r瓜ng ph衣m vi nhóm th院 trên các d磯n xu医t c栄a amide và aniline, c映 th吋 là v噂i các aniline d鵜 vòng e pi"u胤 c亥p"8逢嬰c chú ý.
DANH M影E"EðPI"VTîPJ"AÊ"EðPI"D渦
1. K. M. Tran, N. T. Ho, T. T. T. Le, T. T. Nguyen and P0"V0"U0"Rjcp."ÐEqrrgt"Ogfkcvgf."
(2-Methylthio)aniline Directed Annulation of sp2 C-J"dqpfu"ykvj"rtkoct{"cpknkpgu.Ñ"
TÀI LI烏U THAM KH謂O
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