- Khong co dap Un gm iln djch di truyen
3.7. Vacxin chong ky sinh trung trong tuong la
Trong tuong lai, c6ng nghe vacxin chong ky sinh trung chuyen sang viec xac dinh cac ph^n tu khang nguyen dung che vacxin. Muc dich can dat duoc la:
- Chumg minh dugc midn dich bao ho bang viec su dung cac chat chiet hay cac san
pham ky sinh trung.
- Xac dinh cac phan tu bao ho tu nhien.
- Chon cac clone va thd hien cac protein gay midn dich. - Thu nghiem vacxin voi cac protein tai to hgp.
Khai niem "khang nguydn an", "khang nguydn giau" hay "khang nguydn mcri" dugc sir dung khi nguoi ta dung cac khang nguydn song tach ra tu ky sinh trung nhung cac khang nguyen nay binh thugng khong co trdn vat chu. Do la cac khang nguyen tach ra tu mang ong tidu hoa cua ky sinh trung dung che' vacxin chong ky sinh trung do.
Vf du:
- Vacxin che' tu khang nguydn mang ong tieu hoa cua ve Boophilus microplus de tao midn dich chong ve Boophilus microplus (vacxin nay da dugc che tao va thu nghiem d Oc).
- Vacxin che tu phan tu H ll cua mot glycoprotein mang ong tieu hoa cua giun
Haemonchus cotortus.
Theo cac nha khoa hgc, vacxin che' tu “khang nguyen giau”, "khang nguydn an" hay "khang nguydn moi" cho hieu luc cao, kha nang bao ho tot, co thd dung cho gia sue non cung cho hieu qua tot. Dong thoi, mot khi da xac dinh dugc khang nguydn bao ho cho mot loai thi co the lam thu giong nhu vay trdn mot loai khac. Nhu vay, trong tuong lai, vacxin tai to hgp chong ky sinh trung se dugc chu y nghidn cuu su dung, gop phan quan trong trong viec khong che benh ky sinh trung 6 vat nuoi.
TAI LIEU THAM KHAO PHAN THtTNHAT (CHUONG 1, 2, 3, 4, 5) * Tieng Viet <■,
1. Vu Trieu An, Jean Claude Homberg (1997), Mien dich hoc, Nha xuat ban y hoc. H i NOi, Tr. 219-224.
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6. Nguydn Thi Le (1998), Ky sinh trung hoc dai cuong, Nha xua't ban Khoa hoc va ky thuat, Ha N6i, Tr. 8 - 74.
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* Tieng A nh
10. Urquhart G. M, Armour J., Duncan J. L., Dunn A. M., Jennings F. W. (1996), Veterinary Parasitology, Blackwell Scienc, P. 5 - 20.