- Khong co dap Un gm iln djch di truyen
3.5. Vacxin chdng don bao ky sinh
3.5.1. Vacxin chong le dang trung - Vacxin nhugc doc chong le dang triing
Vacxin duoc che tao tir cac chiing Babesia bovis. Babesia bigemina giam doc luc bang cach truyen qua be dugc cat lach. Vacxin nay sir dung phong benh le dang triing co hieu qua nhirng co mot so nhugc diem nhu sau: bao quan kho, gia thanh cao; cac don bao da nhugc doc co the’ chuyen thanh co doc luc trong co the’ gia sue va gav benh; co the gay hoang dan do dung huyet d be sir dung vacxin.
- Vacxin chdt chong 16 dang triing: duoc ch£ tao tir nhiing chung Babesia bovis, B. canis. Vacxin nay su dung nhung khang nguydn san xua't trdn mdi trudng in vitro. Tuy
nhien, thuc nghiem cho tha'y, viec su dung vacxin nay hieu qua khdng cao. - Vacxin chong le dang trung su dung cac protein tai 16 hop khac nhau.
Vacxin nay cho ket qua bao hd td't, nhung c£n phai cd chat b6 tro Freund trong ch£ tao vacxin.
Hien nay, cd mot so nghien cuu dang duoc tien hanh vdi muc dich thay the chat b6 tro Freund bang chat bo tro khac, budc ddu cho ket qua cd th i cha'p nhan duoc.
3.5.2. Vacxin chong Theileria
- Vacxin nhugc doc chong Theileria annulata va Theileria hirci
Vacxin dugc che tao bang cac chung Theileria annulata va Theileria hirci duoc giam doc luc bang viec nudi ca'y va tiep ddi in vitro cac Schizonte cua cac don bao nay.
Vacxin loai nay cho hieu qua phong chac chan doi vdi Theileriosis.
- Vacxin tai td hgp chong Theileria: dugc che tao tir don bao Theileria parva.
Budc dau vacxin tai t6 hgp chong Theileria parva cho ket qua bao ho tot.
3.5.3. Vacxin chdng cau trung ga
De gay midn dich chong c<iu trung ga, cd the dung lieu nho cac Oocyst cd sue gay benh cho ga nuot. Song, lam nhu vay kho va nguy hiem vi ga dd bi benh cau trimg.
Vi vay, cung cd the dung Oocyst gay benh de gay nhidm thuc nghiem, sau dd dung hoa dugc dieu tri cho ga mac benh.
Ngoai ra, cho den nay mot sd vacxin chong cau trung ga da dugc che tao. tuy nhien hieu luc cdn thap.
- Vacxin nhugc doc: dugc san xuat tu nhung san pham cua giai doan sinh san vd tmh ciia cau trung, chung ft doc nhung van cd kha nang kfch thich co thd tao midn dich.
- Vacxin tai to hgp: nhieu loai vacxin tai td hgp duoc nghien cuu che tao, nhung nhin chung cdn phai khac phuc mot so han che nhu: kha nang bao hd yeu, dudng dua vacxin phai cai tien, su thay doi tfnh khang nguydn giua cac chung cau trung.