you are calm in the centre of chaos

... Increasing interaction • Ask five people… – How long they have been teaching – Where their family lives – If they are enjoying themselves • Find someone who… – likes the same kind of movies as you ... centre of chaos Settle: You are active while tasks are being completed Paired Heads Together are better than one • Why is it good to find people who are the same as you? – Humans love sharing similar ... and measure their work against •H A P P Y Spencer Kagan: www.kaganonline.com • the single most powerful determinant of the cooperativeness of children is the situations in which they are placed...

Ngày tải lên: 13/06/2015, 02:00

... for the binding of 4.40 kcal mol1 of the next minimum i The next minimum j repeats some of the prior interactions, including the donation from both the CO p and p* orbitals into s*(SS) A new interaction ... S-containing protein residues Most of the minima are characterized by the presence of multiple stabilizing interactions, all contributing to the total binding In addition to H-bonds of the SHãããO, ... is worth the stretching and bending of the SHãããO in b The next minimum on the surface, bound by 4.06 kcal mol1, is reminiscent of the global minimum in terms of its constituent stabilizing forces...

Ngày tải lên: 16/12/2012, 15:21

... victory of men over women, re¯ecting the strategic interests of men in keeping women in their place Insofar as it was the gender interests of men that formed the basis for the struggle over the family ... discussion of the origins of male domination, for example, explains the subordination of women in terms of its effects on stabilizing the inheritance of private property This is an explanation of gender ... this in turn is to be explained by the fact that the unpaid domestic labor of women raises the rate of pro®t by lowering the costs of reproducing labor power (since part of the consumption of workers...

Ngày tải lên: 01/11/2013, 07:20

... admins can now install, maintain, and remove most servers within their own administrative group However, there are still exceptions: You still need full org admin permissions when installing the ... in the same domain as the installing server (ScPRQ_ChosenDCMustBeInSameDomain is the prerequisite check which enforces same-domain domain controller) One good use of this switch is when you are ... the values you converted in step 10 Hit the FIND button, and you will be presented with the new name of the group (if it has been renamed) 11 To determine the OU in which it resides, choose the...

Ngày tải lên: 11/12/2013, 14:15

... admins can now install, maintain, and remove most servers within their own administrative group However, there are still exceptions: You still need full org admin permissions when installing the ... in the same domain as the installing server (ScPRQ_ChosenDCMustBeInSameDomain is the prerequisite check which enforces same-domain domain controller) One good use of this switch is when you are ... the values you converted in step 10 Hit the FIND button, and you will be presented with the new name of the group (if it has been renamed) 11 To determine the OU in which it resides, choose the...

Ngày tải lên: 18/01/2014, 05:20

... (AHA1) interacts with the first 88 amino acids of PPI1 [22], indicating that the PM H+-ATPase binding site of PPI1 is localized therein Indeed, fusion proteins containing the first 88 amino acids of ... C-terminus, but further enhances the activity of the enzyme whose C-terminus has been displaced by low pH or by FC-induced binding of 14-3-3s Results The C-terminus of isoform of the PM H+-ATPase of ... cleavage of the enzyme, indicating that the PPI1 binding site in the H+-ATPase C-terminus is localized upstream of the main tryptic cleavage site and thus is different from the 14-3-3 binding site...

Ngày tải lên: 19/02/2014, 07:20

... shown) The basic cluster of amino acids in the binding groove of 14-3-3, including amino acids Lys-49, Arg56, Lys-120 and Arg-127, in an otherwise acidic molecule, are important for the interaction ... strategy of single amino acid site-directed mutagenesis Delineation of ExoS residues of the cofactor interaction domain within ExoS Various single mutant ExoS proteins were tested for their capacity ... define individual residues within the 14-3-3 binding domain of ExoS that are important for the 14-3-3 interaction, as well as the resultant activity in vivo We have approached these questions using...

Ngày tải lên: 19/02/2014, 08:20

... residues known to be involved in binding and hydrolysis of the guanidino group of l-arginine by arginase are strictly conserved in the active site of the agmatinases [19] Moreover, modeling studies have ... agmatine hydrolysis, in studying the inhibitory effect of agmatine on arginine hydrolysis, reactions were followed by measuring the formation of ornithine, determined by the method of Chinard ... totally inactive in the absence of added Mn2+ At the optimum pH, the Km for agmatine (2.5 ± 0.2 mm) was very close to the Km of the wild-type arginase for arginine However, the hydrolytic activity of...

Ngày tải lên: 20/02/2014, 02:21

... plastocyanins has been described [1] Representations of the electrostatic surfaces showing the changes introduced by the mutations are displayed in Fig The decay of the flash-induced absorbance of P+ ... direction The inverse is the case for the attraction in the case of Anabaena Also, if the structure of the final complex in which electron transfer takes place remained unaltered with increasing ionic ... laminosum and spinach The response to ionic strength of the reaction between P laminosum plastocyanin and photosystem I was in marked contrast with the behaviour of the homologous system in spinach...

Ngày tải lên: 21/02/2014, 01:21

... transferrin required for the binding of gastrin, and of the regions in gastrin required for the interaction with transferrin, is obviously essential to a full understanding of the interaction The independent ... Ggly–transferrin interaction, to define the domains ⁄ residues of Ggly involved in the interaction (using Ggly mutants), and, finally, to determine the regions of transferrin required for the interaction ... [12] In order to determine whether both of these iron-binding sites are involved in the interaction with transferrin, we used Ggly mutants in which the glutamates had been mutated to alanines...

Ngày tải lên: 07/03/2014, 02:20

... shown in light green, the compensatory mutations are shown in pink, and the hinge region of the ISP is shown in white the integration or stability of the ISP within the bc1 complex In order to investigate ... enzyme with their ISP in different conformations The mutation G167E could distort the hinge region of the ISP and hinder the movement of the headgroup Mutations in the hinge region of the ISP, which ... amplitude, 1.6 mT ISP–cytochrome b interaction at the hinge region Movement of the extrinsic domain of the ISP is facilitated by the unwinding of a single turn of the 310 helix formed from ˚ residues...

Ngày tải lên: 07/03/2014, 15:20

... hydrolysis of the nucleotide To investigate the in uence of the binding and ⁄ or hydrolysis of ATP on the interaction of the AAA-peroxins, Pex1p and Pex6p carrying mutated ATP-binding sites were ... fused to the coding sequence of the activation domain of Gal4p (PEX1-GAL4-AD) or PEX6 linked to the coding region of the DNA binding domain of Gal4p (PEX6-GAL4-BD) The two-hybrid reporter strain PCY2 ... sites were tested for interaction with the binding partner in the yeast two-hybrid system In the first set of mutants, the lysine residue in the GXXGXGKT sequence of either one of the two WalkerA motifs...

Ngày tải lên: 07/03/2014, 16:20

... ATP into contact in the absence of ATP, curcumin is then able to bind to the ATPase (possibly at the hinge region) locking the two domains together and therefore precluding ATP binding (i.e inhibiting ... curcumin The binding inhibition had a apparent Ki (IC50) of about mM Reversing the order of addition to the ATPase (i.e curcumin then ATP) had a similar effect on the extent of ATP binding, i.e in ... side of the membrane While in the E2 form the Ca2þ binding sites have translocated across the membrane to the luminal side and are of low affinity Furthermore, in the E1 conformational state, the...

Ngày tải lên: 08/03/2014, 23:20

... calibration The results of calibration of the wind fields show that the typhoon model of Boose given a good simulation of wind velocity in the Hon Dau station for the two storms [11] Therefore, this ... with the total storm surge There was a maximum of the total storm surge at the Lach Tray estuary, but the maximum of wavesetup was at the Van Uc estuary, where also appears the highest value of the ... show the results of wave-setup by different methods for several points in Hai Phong and the results of calculating storm surge by the ADCIRC model Assessment of contribution of wave-setup to the...

Ngày tải lên: 14/03/2014, 15:20

Ngày tải lên: 16/03/2014, 00:07

... transcend the individual interest in the exploitation of intellectual property in that the number of participants is unlimited and the aim is to advance the functionality of the software in the common ... provide the rules for determining the optimal interaction16 between the two bodies of law The Areas of Interaction The transactional context of intellectual property-related restrictions of competition ... societies29 or of the enforcement of plant breeders rights,30 the legitimizing rationale being the insuperable transaction costs of individually controlling the multiplicity of uses and users of the protected...

Ngày tải lên: 16/03/2014, 12:20

... [15] In order to identify the specific amino acids within the linear interacting epitopes involved in the complex between a-DG and b-DG, alanine scanning of some of the residues that were mainly in uenced ... peptides spanning the C-terminal domain of a-DG and the b-DG ectodomain by solid-phase binding assays and SPR, demonstrating that despite the intrinsic pitfalls of solid-phase binding techniques, ... belonging to the putative a-DG-binding epitope (691–719) within the ectodomain of b-DG, was found to be one of the most in uenced residues during the titration of [15N]b-DG(654–750) with thioredoxin-a-DG(485–620)...

Ngày tải lên: 16/03/2014, 12:20

... (D) The experimental data were analysed using global fitting assuming a : interaction In all plots, the arrow on the left indicates the beginning of the association phase; the beginning of the ... This indicates that the inaccessibility of the C-terminus of CP12 to thioredoxin in the GAPDH ⁄ CP12 complex is specifically due to the interaction of CP12 with GAPDH Impact of cysteine residues of ... classification are one of the most challenging undertakings of structural biology in the years ahead The first major stumbling block encountered by the researcher interested in characterizing protein–protein...

Ngày tải lên: 16/03/2014, 13:20

... conditions of alteration of workloads, in addition to the effects of calcium, the metabolic channelling of the endogenous ADP by the organized energy transfer and signalling networks (the creatine kinase, ... changes in the kinetics of regulation of the respiration rate (Fig 6) This concerned mostly the changes in the apparent afnities for the exogenous adenine nucleotides: a very strong decrease in the ... decrease in the Vmax of respiration with an increase in the free calcium concentration (Fig 6A) is of interest, and may be explained by an inhibitory effect of increased calcium concentration in the...

Ngày tải lên: 16/03/2014, 22:20

... that of the active area in insulin (Fig 7F) If the mechanism of the interaction between the 4-kDa peptide and 43-kDa protein has the minimum components of insulin–insulin receptor interaction, the ... impairment in binding of the 43-kDa protein, i.e greater than a fourfold increase in the Kd value Three of the 13 variants (Asp2, Asn4 and Ser8) are located in the N-terminus of the 4-kDa peptide and their ... similar to the insulin– insulin receptor interaction system Interaction of insulin with the 43-kDa protein Acknowledgements Similarly to the 4-kDa peptide, insulin is able to interact with the 43-kDa...

Ngày tải lên: 17/03/2014, 03:20