y học chứng cớ

... incidents in this region. The purpose of this study was to find whether this institution has achieved its primary tasks by analyzing its registry during January 1 st 2006 until December 31 st 2008. Setting According ... missions have been a visit by NATO military ships (15 days), storm with flooding (12 days), European Championship in track and field sports (10 days) as well as a bus crash (10 days). Since some of these events ... together with executive responsibility at the time of disaster may not only reveal various short- comings within our organizations and the healthcare sys- tem, but may also prevent the disastrous outcome...

Ngày tải lên: 25/10/2012, 09:56

... mitochondrial enzyme defi- ciency, Reye's syndrome, Friedreich's ataxia, a sibling affected by valproate hepatotoxicity, or multiple drug therapy, as well as children younger than 3 years of ... Elevated frequency of diabetes mellitus in hospitalized manic-depressive patients. Am J Psychiatry 1999, 156:1417-1420. 25. Yang SH, McNeely MJ: Rhabdomyolysis, pancreatitis, and hyperglycemia with ... pathology, such as recurrent syncope. A family history of early sudden death should be obtained and serum electrolyte imbalances should also be corrected as these may predispose patients to arrhythmias....

Ngày tải lên: 25/10/2012, 10:51

... Cen- tral Microbiology Laboratory of Selcuk University Meram Faculty of Medicine from various clinics were included in the study and kept at -70ºC until per- forming laboratory study. Coombs anti-brucella ... than one by one increases their sensitivity and specificity values. The Ig G and Ig M sensitivities found in our study were higher in comparison to the study in question but specificity is lower. ... analyzed by using the paired t test method on SPSS for Windows 13.0 software. This study was approved by the local institutional ethics committee of the Selcuk University Meram Faculty of...

Ngày tải lên: 25/10/2012, 10:56

... study was designed to compare the safety and efficacy of three bone health Plans using three independent sequentially enrolled groups of healthy women 40 years of age and older. The pri- mary ... interventions, the acceptability of an in- tervention becomes heavily dependent upon a com- pany‟s marketing capability, as opposed to product superiority proven with safety and efficacy test results [36]. ... AlgaeCal; BMD: Total Body Bone Mineral Density; SG: United States Surgeon General; CER: Comparative Effective Research; DXA: Total Body Dual-energy X-ray Absorptiometry; MAPC: Mean Annualized...

Ngày tải lên: 25/10/2012, 11:10

... efficacy of decompressive craniectomy in decreasing ICP and improving pr o g n o sis in patients wi th refractory in- tracranial hypertension after TBI. 2-8 Presently, th e European Brain Injury ... skin flap concavity, the hydrodynamic distur- bance of CSF circulation and the decrease in cortical perfusion after decompressive craniec to my may also hinder patient recovery. 3 6 -37 A method ... craniectomy. Compared with a control group consisting of 29 pa- tients who underwent ordinary large decompressive craniectomy, they found that cranioplasty in the pa- tients in their study group...

Ngày tải lên: 25/10/2012, 11:40

... particular cause, treatment options may strongly vary. In case of patient incom- pliance or inability to put partial weight bearing on the operated extremity, the patient should be rather considered ... resection arthroplasty. A spacer fracture can be either symptomatic or asymptomatic depending on the fracture localisation. Symptomatic fractures (Figure 5) are usually the con- sequence of ... Steinmann pins, intrame- dullary nails with two lag screws and Charnley prostheses, respectively [5]. The authors reported that all constructs based upon the Charnley prostheses and the commercial...

Ngày tải lên: 26/10/2012, 09:53

... within the system’s evolutionary phase, reaches its greatest functionality, the orderly complexity within the health territory, and then steadily declines during sys- tem’s devoluti onary phase ... a human body. By extrapolation, similarities may also be seen in the fields of physics, business, and psy- chology with model polarity encompassing infla- tion/deflation, anxiety/depression, ... system. Redundancy is needed to maintain resiliency of a sys- tem. With diminishing redundancy, resiliency falters. In general, this is true in the early and latter phase of biologic entity’s...

Ngày tải lên: 26/10/2012, 10:04

... kinases phosphorylation. The most strikingly and novel finding obtained hereby was the strong inhibition of the GPCR signaling pathway induced mainly by increased phosphorylation of GRK2. ... Laboratory for Molecular Pathobiochemistry and Clinical Research, Max Planck Institute of Molecular Physiology, Dortmund, Germany Correspondence to: Francisco Castaneda, MD, Laboratory for Molecular ... complex by MEKK1, a kinase of the JNK pathway. Cell 1997;88:213-22. 35. Marusawa H, Hijikata M, Watashi K, et al. Regulation of Fas-mediated apoptosis by NF-kappaB activity in human hepatocyte...

Ngày tải lên: 31/10/2012, 15:37

... variety of anti-staphylococcal antibodies [26]. Despite the complexity of immune response many polypeptides in the cell extract gave negative reaction in the western blot analysis. It is likely ... statistical analysis, David Griffith for photography and Dr. Fu-Shin Yu (Kresge Eye Institute) for his valuable critiques. Conflict of interest None declared. References 1. Lowy FD. Staphylococcus ... osteomyelitis. J Clin Microbiol 1987, 25(1):122-127. 11. Granstrom M, Julander I, Mollby R. Serological diagnosis of deep Staphylococcus aureus infections by enzyme-linked immunosorbent assay...

Ngày tải lên: 02/11/2012, 11:08

... thickness have a good reproducibility as demon- strated in repeated examinations. The main applica- tion of OCT in inflammatory eye diseases is for the analysis of cystoid macular edema [2;3]. Ocular ... fluid was detected by OCT in 3 cases, but was present on fluorescein an- giograms only in 2 of these cases (Figure 1). Scarred areas were characterized by retinal atrophy. The mean retinal ... of the underlying choroidal tis- sue. Reliable measurements of retinal thickness by OCT may be impossible in the presence of severe vitritis. Fluorescein angiograms remain very useful for...

Ngày tải lên: 03/11/2012, 11:01

... °C. The carboxymethyl dextran matrix of the sensor chip was activated by a 30-lL injection of the mixture of 0.2 M 1-ethyl-3-[(3-dimethylamino)propyl]carbodiimide and 0.05 M N-hydroxysuccinimide ... aminoacyl-tRNA synthetase Implications for tRNA channeling Zoya M. Petrushenko, Tatyana V. Budkevich, Vyacheslav F. Shalak, Boris S. Negrutskii and Anna V. El’skaya Institute of Molecular Biology ... (1988) Effects of the ligands of beef tryptophanyl-tRNA synthetase on the elementary steps of the tRNA Trp aminoacylation. Biochemistry 27, 2244–2252. 36. Sang, L.J., Gyu, P.S., Park, H., Seol, W., Lee,...

Ngày tải lên: 21/02/2014, 15:20

... dehydrogenase activity was partially restored by treatment with T ween 40. Computer analysis of the Phyco- myces phytoene dehydrogenase deduced protein sequence identi®es several myristoylation sites ... phytoene synthase, phytoene dehydrogenase and lycopene cyclase. The enzyme phytoene dehydrogenase is able to introduce four dehydrogenations in a s ubstrate molecule to produce lycopene. Its coding ... of Mucor and Phycomyces, respectively, are white, accumulate no caro- tenoid or only traces of b-carotene, and are altered in t he enzyme phytoene synthase [15,22,29]. In Phycomyces,white carB...

Ngày tải lên: 22/02/2014, 04:20

... (R.)-lactyl-CoA dehydra- tase from Clostridium propionicum. Stereochem istry of the dehy- dration of (R)-2-hydroxybutyryl-CoA to croton yl-CoA. Eur. J. Biochem. 206, 547±552. 20. Kelley, L.A., ... spect- rometry [14]. Alternatively the mixed anhydride interme- diates can be detected by the formation of stable derivatives of the catalytic glutamate and hydroxamic acids [15] or indirectly by oxygen ... cultures (DSMZ, Braunsc hweig, Germany). Synthesis of acyl-CoA substrates Acetyl-, butyryl- and propionyl-CoA were prepared from the corresponding anhyd rides and CoA by the method of Simon & Shemin...

Ngày tải lên: 17/03/2014, 17:20

... and 20% poly(ethylene glycol) 400. The crystallization drops were made with equal volumes of protein and well solution. Crystallization of *YpCM Crystallization conditions were surveyed by the hanging drop ... gene, respectively. The plasmid vector pG58 and subtilisin column were kindly provided by P. N. Bryan (Center for Advanced Research in Biotechnology, University of Mary- land Biotechnology Institute). ... shikimate pathway enzyme [1], catalyzes the pericyclic rearrange- ment of chorismate to prephenate [2]. Subsequent to this conversion, prephenate dehydrogenase and prephenate dehydratase catalyze the biosynthesis...

Ngày tải lên: 17/03/2014, 17:20

Ngày tải lên: 24/03/2014, 04:21

Ngày tải lên: 24/03/2014, 04:21

Ngày tải lên: 31/03/2014, 15:20

Ngày tải lên: 31/03/2014, 23:20

Ngày tải lên: 31/03/2014, 23:20

Ngày tải lên: 30/05/2014, 07:28