... social science and indeed even within lay discourse with a pro-feminist position,insofar as it recognises the historical dominance of men. In addition, and not from a feminist perspective, there is also ... mighthelp and so on. There is, therefore, an increasing interest in understanding thefunction of talk in terms of establishing moral worth and discursiveconstructions.We have sought to outline a ... as failing in herexpected role of servicing children and the father was constructed as (surpris-ingly) capable in contrast.Discourses of femininity are also very importantin understanding theproblems...
... Difficulties Meeting Future Health NeedsFailing the Health and Social Care WorkforceIncreasing Pressure on HealthandSocial Care Instability in the Health andSocial Care System ... hospital care; ã care of the elderly (including domiciliary and community care) ; ã waiting times; ã cancer services; ã mental healthand learning disability; ã healthandsocialcare staffing ... The Minister’s over-riding concern is driving up the quality of care for clients and patients, improving outcomes and enhancing the patient experience. In initiating the Review, the Minister...
... their understanding of a health concept. Cubing is a second powerful differentiation tool that provides a new twist on question asking and answering, and works well in a healthand physical ... successful decision making; ã explain the advantages, disadvantages, and possible consequences of risk-taking behaviour; ã describe how to determine whether a risk is worth taking or not. CUBING ... determine if a risk is worth taking? Analyze the relationship between physical activity, healthy eating and self-image. In your opinion, what is the most destructive risk taking behavior...
... involved in ligandbinding, presumably abolishing the interaction withsignaling partners. The remaining mutations alteramino acids located outside the ligand-binding pocket and reduce protein stability.The ... locationsof the missense mutation in the BTK PH domain; arginine 28 is in dark blue, encircled in red. Bottom left: SH2 domain. Right: kinasedomain. The mutated residues are indicated in yellow, a-helices ... HIV and also have anti -in ammatory activity. Since 2006, several patients carry-ing a fusion protein, originating from a translocation joining genes encodingthe kinases ITK and spleen tyrosine...
... focusing onaging and disability and the demands older people and the disabled make on health and other services. In IIASA’s model, the world is divided into two regions. Oneregion comprises ... A., Normand, C., Dror, D., and Preker,A., 1999, Modeling inHealthCare Finance: A Compendium of Quantitative Tech-niques for HealthCare Financing, International Labour Office and International ... have been in containing heath care costs. First, health care is, to a significant degree, demand driven, as those who would not otherwiseconsume healthcare do so as their incomes rise, as services...
... options and marketing streams based on a firm understanding of the major consumer health concerns influencing purchasing decisions and eating habits. Identifying the main health- related issues influencing ... but also assist in targeted, intelligent marketing and advertising plans. Health is a ‘glocal’ concern - while many food and drinks issues and regulations remain local, health continues to be ... concerns and healthy issues industry opinion survey, August 2004 Business Insights Obesity case study: Weight Watchers’ reinvention Weight Watchers is an established brand, diet and product in 30...
... myofibrillar protein from tissues containing myosin and actin (muscle, smooth muscle such as gut, skin). In man, 3-methylhistidine is quantitatively excreted into urine; in rat, 3-methylhistidine is also ... of Free Amino Acids in the BodyIt isimportant to bear in mind the differences in the relative amounts of N contained in extracellular and intracellular amino acid pools andin protein itself. ... limiting amino acid is the protein's score. Typically, the limiting amino acids in dietary proteins are lysine, the sulfur-containing amino acids, threonine, and/ or tryptophan. The BCAAs and phenylalanine/tyrosine...
... be applied to health care? One of the things that distinguishes healthcare from, for example, the disk-drive industry that Christensen studied, is that the healthcare industry is regulated, ... prospective clinical trials on the effectiveness of the dis-tinct features of ECG in improving clinical outcomes over standard cardiac event-monitoring services. What this payer is saying, in other ... endpoint of the translation pathway illustrated in Figure 2-1 is public and global health. There is a growing convergence between national healthcare issues and global ones. As is the case in...
... matrilysins (MMP-7 and -26) and MMP-23 contain a C-terminal hemopex- in (HPX)-like domain that is linked to the catalyticdomain through a hinge region. In most MMPs, thishinge region consists ... integrin-binding ligandN-linked glycoprotein (SIBLING)Individual members of the SIBLING family are knownto bind strongly to both pro- and active forms ofspecific MMPs. Bone sialoprotein binds ... lacking the HPX domain, which is replaced by a C-terminal cystein array region and animmunoglobulin G-like domain, and, instead of theN-terminal signal peptide, this enzyme contains anN-terminal...
... CouncilPoisoning the Well: How the EPA is Ignoring AtrazineContamination in Surface and DrinkingWater in the Central United StatesNRDC ReportAugust 2009The full report on atrazine contamination ... running annual averages for atrazine in finished (tap) water7 that exceeded the 3 ppb drinking water standard: Versailles Water Works in Indiana (4.60 ppb), Mount Olive Water Works in Illinois ... phasing out the use of atrazine, more effective atrazine monitoring, the adoption of farming techniques that can help minimize the use of atrazine and prevent it from running into waterways, and...
... homeostasis.5. ION HOMEOSTASIS AND NEUROLOGICAL DISEASESubstantial progress has been made in the understanding of the pathophysiology and mechanisms involved in the attenuation of brain homeostasis. ... and mRNA binding to cytosolic and poly-some proteins in brain and peripheral tissues. Brain Res. Mol. Brain Res. 58, 170–177.39. Lauger, P. (1991) Na,K-ATPase, in Electrogenic Ion Pumps, Sinauer, ... sustain the requiredlevel of metabolites and to remove waste products.The Neuronal Environment: Brain Homeostasis inHealthand Diseaseexamines the function of all the components involved, including...
... signalingbetween lumican and decorin is also supported byrecent studies showing the involvement of decorin in modulating various integrins in controlling prolifera-tion, adhesion and migration [60,83]. ... with the EGF-binding domain [32]. Thestructural constraints of the EGFR binding regionsupport a stochiometry of 1 : 1 for the decorin pro-tein core and EGFR, suggesting that decorin is bio-logically ... pathways involved in decorin catabolism. The endocytosis and lysosomaldegradation of decorin comprises multiple pathwaysincluding those mediated by the EGFR [34] and low-density lipoprotein receptor-related...
... Zonulaoccludens-domain-containing proteins such as syntenin,Ga-interacting protein (GAIP)-interacting C-terminus ⁄synectin and calc ium ⁄ calmodulin-associated serine kinase,since the C2 region contains a ... (TACE) and aggre-canases [27,30]. All mammalian TIMPs consist of twodistinct domains, N-terminal ( 125 amino acids) and C-terminal ( 65 amino acids), where the N-terminaldomain usually is responsible ... [124].Conclusions and perspectivesSyndecan shedding is subject to highly complex regula-tion. In tissue culture, there may be constitutive shed-ding, andin vivo enhanced shedding in cases of injury and disease....
... in lungcarcinoma and chronic myeloid leukemia comparedwith control tissue and cells. In this splice variant,144 bp of intron 5 are joined with exon 4, resulting in a 169-amino-acids protein ... Accumulating evidences indicate thatHSPGs act to inhibit cellular invasion by promotingtight cell–cell and cell–ECM interactions, and by main-taining the structural integrity and self-assembly ... to be misregulat-ed in cancer; it is present in a variety of normal tissuesbut is downregulated in cell lines originating fromovarian, breast, pancreatic, renal and hepatocellularcarcinomas...
... extent.Richersocietiescanaffordtooffsetrises in incomeinequalitybyprovidingmore health servicesaspublicgoods.Butincreasing health expendituredoesnotnecessarilydemand high national income. This is clear ... Progress in increasingskilledbirthattendance 20FigureI-7 Progress in expandingantenatal care 22FigureI-8 Progress in improvingaccesstosafedrinkingwater 24FigureI-9 Progress in expandingaccesstobasicsanitation ... twolargecountriesFigureII-17 Health- relateddisparitiesacrossjurisdictions in twosmallcountries 42FigureII-18Disparities and attainment in health- relatedMDGtargets 44FigureII-19Driversof disparities in underweightprevalenceamong...