what is understood by the concept of global civil society
Tài liệu Báo cáo Y học: Thermostability of manganese- and iron-superoxide dismutases from Escherichia coli is determined by the characteristic position of a glutamine residue pdf
... SODs is not governed by one or even two residues, but is most likely accomplished by the concerted effects of a combination of key residues. Further analysis of these and other mutant SODs is currently ... with the iron metal at the active site. The presence of iron is therefore a prerequisite for its effect and suggests that the absence of reactivity with the MnSOD mutants is due to the lack of ... which is structurally equivalent in the enzymes, is contributed by the N domain of FeSODs (Q69) and the C domain of MnSODs (Q146). Exceptions to this scheme include the substitution of Gln by His...
Ngày tải lên: 21/02/2014, 01:21
Báo cáo khoa học: A region within the C-terminal domain of Ure2p is shown to interact with the molecular chaperone Ssa1p by the use of cross-linkers and mass spectrometry doc
... France Introduction The aggregation of the prion Ure2p is at the origin of the [URE3] trait in the baker’s yeast Saccharomyces cerevisiae [1,2]. The propagation of the prion element [URE3] is highly dependent ... peptides. This model was built from the X-ray structure of the C-terminal domain of Ure2p and integrates the finding that the N-terminal domain of Ure2p is flexible. An enlargement of the region of Ure2p ... within the same area in the 3D structure of Ure2p. Thus, the binding of Ssa1p to the region centered on lysine 339 could abolish the acquisition by Ure2p of an assembly competent state. The results...
Ngày tải lên: 15/03/2014, 00:20
Báo cáo khoa học: The expression of retinoblastoma and Sp1 is increased by low concentrations of cyclin-dependent kinase inhibitors ppt
... doi:10.1046/j.1432-1033.2003.03874.x Therefore, the effect of UCN-01 on the levels of Rb protein may be caused by an increase in the synthesis of Rb and by a decrease in its degradation. However, the effect on Sp1 ... shown by the luciferase experiments and in the levels of Rb mRNA; and, on the other hand, the stability of Rb protein is increased. As stated in the Introduction, Rb interacts with a variety of ... a positive effect caused by accumulation of the hypophosphorylated form or by a combination of the two mechanisms, in keeping with the self-regulation of the Rb gene by its own gene product,...
Ngày tải lên: 16/03/2014, 23:20
Báo cáo khoa học: Proteolytic degradation of nitric oxide synthase isoforms by calpain is modulated by the expression levels of HSP90 potx
Ngày tải lên: 23/03/2014, 07:20
Báo cáo khoa học: The phosphatidylethanolamine level of yeast mitochondria is affected by the mitochondrial components Oxa1p and Yme1p ppt
Ngày tải lên: 30/03/2014, 04:20
Báo cáo y học: "JNK pathway is involved in the inhibition of inflammatory target gene expression and NF-kappaB activation by melittin" ppsx
Ngày tải lên: 11/08/2014, 08:22
The Lure of Global Branding
... equity. At Smirnoff, the global brand manager is given the title of president of the Pierre Smirnoff Company, suggesting how much the company values his position. A global brand ... Brazil is a hotbed for swimsuit design. Similarly, the French brand manager takes the lead for Lycra used in fashion. The idea is to use the expertise that is dispersed through- out the world. The global ... P&L.” The P&L measures brand equity by tracking the results of blind taste tests, the extent of a product’s distribution, and the results of cus- tomer opinion surveys about the brand. In the...
Ngày tải lên: 24/10/2013, 08:20
KRONE - What is Patch by Exception
... moves offices, their extension number can be easily reallocated using the software on the PABX. The significance of these facts, is that office buildings can be cabled using jumper wire in the ... to the network simply requires the person to plug their computer into the port provided. Another development that will contribute to the patch by exception solution is the impending release of ... significantly due to the economy of using jumper cable instead of patch cords. The cost of category 5 jumper cable is approximately one tenth of the cost of an equivalent patch cord. For further cost reductions...
Ngày tải lên: 26/10/2013, 19:15
Tài liệu TRANSFER CREDIT SERVICES GUIDE: Produced by the Office of the Registrar ppt
... send their AP results to the Office of the Registrar as follows: Prospective/Entering Continuing/Returning Berklee College of Music Berklee College of Music Office of Admissions Office of ... university should have their official transcripts mailed directly to the Office of the Registrar at the following address: Berklee College of Music Office of the Registrar Page -6- ATTN: ... Coordinator in the Office of the Registrar. Page -8- Degree Program Below is a list of the Liberal Arts requirements for the Berklee Degree program. These are provided to assist you in...
Ngày tải lên: 15/02/2014, 14:20
Tài liệu Báo cáo khoa học: Olfactory receptor signaling is regulated by the post-synaptic density 95, Drosophila discs large, zona-occludens 1 (PDZ) scaffold multi-PDZ domain protein 1 pptx
... signal is impaired. We finally examined the effect of deletion of the components of the PDZ binding motif on the signal- ing properties of the receptor in Ca 2+ imaging experiments. Truncation of the ... and have elucidated the molecular details of this interaction. The primary source of olfactory signaling and the sites of expression of ORs are the ciliary structures of the OSNs. Interestingly, ... ORs. The observed effects can therefore only be taken as proof of the functional significance of the observed interac- tion. Further studies are necessary to shed light on the function of this interaction...
Ngày tải lên: 18/02/2014, 13:20
Tài liệu Báo cáo khoa học: Induction of uPA gene expression by the blockage of E-cadherin via Src- and Shc-dependent Erk signaling docx
... suppressed the disruption of cell–cell adhesion, the scattered phenotype of the cells and the redistribution of E-cadherin into the cytoplasm (Fig. 5C). C ab c f e d g hi lk j A B Fig. 5. Involvement of ... contradictory that Erk is also activated upon re-establishment of cell–cell adhesion. However, the duration of this activation is much shorter and the underlying molecular mechanisms of the two systems are ... was necessary for the initiation of the signa- ling pathway, cell scattering and the redistribution of E-cadherin into the cytoplasm. However, the mechan- ism of Src activation by Decma treatment...
Ngày tải lên: 19/02/2014, 05:20
Tài liệu Báo cáo Y học: The insert within the catalytic domain of tripeptidyl-peptidase II is important for the formation of the active complex potx
... that the fo rmation of the active complex is profoundly influenced by a single amino acid difference, i.e. G252R, in a region within the catalytic domain. This is the first evidence that this region ... 6]. Identification of the region causing different association characteristics The difference in association characteristics of the enzyme from the two sources was surprising because the sequence is extremely ... model, but as Arg252 is so close to H is2 64, where the structure is conserved, the model is still expected to be useful. In this model, Arg252 is predicted to be on the surface of the enzyme where...
Ngày tải lên: 21/02/2014, 15:20
21st Century Welfare: Presented to Parliament by the Secretary of State for Work and Pensions by Command of Her Majesty pptx
... ensurethatpeoplecanseethattheclearrewardsfromtakingalltypes of work outweigh the risks; ã furtherincentiviseandencouragehouseholdsandfamiliestomoveinto work and to increase the amount of work they do, by improving the ... into paid work. 8. The next step is to tackle the cost of the system by supporting many more people into work. Alongside the introduction of the Work Programme, we believe there is a strong case ... permission from the copyright holders concerned. ISBN: 9 7 8 0 1 0 1 7 9 1 3 2 8. Printed in the UK for The Stationery Of ce Limited on behalf of the Controller of Her Majesty’s Stationery Of ce....
Ngày tải lên: 06/03/2014, 08:20