Ngày tải lên: 12/08/2014, 23:23
... acetylation of H3 and H4 histones, and the remaining DHSs in the deleted cells were examined to determine the roles of these DHSs on the transcription of Ig-b gene and on the mainten- ance of the active ... levels of b-globin mRNA. However, both the acetylation state of the promoter region of the active b-globin gene [19] and the DNase I general sensitivity in the b-globin locus are the same as the ... Thus, there again has been no description either of the region involved in DNase I general sensitivity or of the region for the formation of DHSs, although chromatin opening activity of the LCR...
Ngày tải lên: 19/02/2014, 16:20
Báo cáo khoa học: Structure of the complex of a yeast glucoamylase with acarbose reveals the presence of a raw starch binding site on the catalytic domain doc
... formed between the enzyme and Tris are the same as observed previously [16]. In the Glu-A complex there are two acarbose mole- cules: one in the active site and the other on the sur- face of the enzyme ... accuracy, shows clearly the influence of cryo-cooling, which is manifested in shrinkage of the mole- cule and lowering the volume of the unit cell. In the structure of the com- plex, two acarbose ... at the opposite end of the barrel to the active site has weaker electron density and the temperature factors of the atoms in this segment are 31 A ˚ 2 , 2.35 times above the average B for the...
Ngày tải lên: 07/03/2014, 12:20
the book of css3 - a developer's guide to the future of web design - by peter gasston
Ngày tải lên: 20/09/2013, 09:09
Tài liệu Cancer Pain Management: A perspective from the British Pain Society, supported by the Association for Palliative Medicine and the Royal College of General Practitioners docx
... from cancer at any stage of the disease with the hope of raising awareness of the types of therapies that may be appropriate and increasing awareness of the role of the pain specialist in cancer ... enlargement of the liver results in the capsule being stretched at the point of the sensory innervation In general, unless there is gross hepatic dysfunction, the metabolism of the common drugs in the ... understanding of their condition. ã what the pain means to the individual and their family. ã how the pain may impact upon relationships within the patients family. ã whether the pain inuences the patients...
Ngày tải lên: 14/02/2014, 21:20
21st Century Welfare: Presented to Parliament by the Secretary of State for Work and Pensions by Command of Her Majesty pptx
... increase the amount of work they do, by improving the rewards from work at low earnings, and helping them keep more of their earnings as they work harder; ã increasefairnessbetweendifferentgroupsofbenetrecipientsandbetween recipients ... is to tackle the cost of the system by supporting many more people into work. Alongside the introduction of the Work Programme, we believe there is a strong case for reforming the system as ... interviews. Figure 4 on the previous page illustrates the current system of conditionality for people on out -of- work benefits. 4. Some of the structural reforms could merge many of these benefits into...
Ngày tải lên: 06/03/2014, 08:20
By the Light of the SoulMary Eleanor Wilkins-Freeman..By the Light of the Soul A Novel By Mary E. Wilkins Freeman Author of “The Debtor” “The Portion of Labor” “Jerome” “A New England Nun” Etc. etc.1907To Harriet and Carolyn Alden..By the Light o pptx
... “A cupful! with coffee at the price it is now? I guess she doesn’t,” said her father. He poured the coffee-pot full of boiling water from the tea-kettle, then he tipped the coffee canister into ... Light of the Soul Mary Eleanor Wilkins-Freeman By the Light of the Soul 23 that every-day occurrence to the watching child. She realized the interminable moving on of things in spite of ... smiles of that baby had not been winning; they had seemed reminiscent of the commonest and coarsest things of life, rather than of heavenly innocence. Maria gazed at the young man on the platform,...
Ngày tải lên: 16/03/2014, 18:20
báo cáo khoa học: " Regulation of hypoxia inducible factor-1a expression by the alteration of redox status in HepG2 cells" pdf
Ngày tải lên: 10/08/2014, 10:21
Common errors in the uses of modal verbs may, might made by the students in the grade 11 at Que Vo high school
Ngày tải lên: 06/10/2014, 16:22
Báo cáo y học: " the Value of Serum Biomarkers (Bc1, Bc2, Bc3) in the Diagnosis of Early Breast Cancer"
... since none of them alone is useful for the majority of the BC and none of them is specific for cancer or breast tissues. No biomarker has been suggested to date for the early diagnosis of BC (24). ... CHAPS) at the ratio of 5:1. Sera were then diluted again with binding solution at the ratio of 10:1 and were applied in 100 µL amounts in the wells on the chip. Protein chips on which the samples ... Bc1 in all groups. The relevance of this finding is that it was the result of the first sub- group analysis for these biomarkers. Bc1 should therefore be studied in terms of tumoral development...
Ngày tải lên: 25/10/2012, 11:15
A STUDY ON THE USE OF PEER TEACHING IN ESP CLASSES AT THE COLLEGE OF SCIENCE, VIETNAM NATIONAL UNIVERSITY HANOI
... to the peer teacher; and 72% of them are motivated by their peers. As for the teachers who were asked about the disadvantages of peer teaching in their ESP lessons which may be the causes of ... design of the study. The second part, the main part, of the study is divided into three chapters. Chapter 1 deals with the review of the literature relevant to the study. Chapter 2 covers the ... It is then approved by all the surveyed teachers. This reveals that both the teachers and students have a good grasp of the role of the learners in ESP teaching. Based on the theory of learner-based...
Ngày tải lên: 29/01/2014, 10:49
Tài liệu Guidelines for the appointment of General Practitioners with Special Interests in the Delivery of Clinical Services pdf
... supervisor/s to confirm the satisfactory fulfilment of the required training experience and the acquisition of the competencies enumerated in this document and others thought necessary by the employing ... areas. The number of sessions should be sufficient to ensure that the GPwSI is able to meet the competencies of the service requirements, the skill being assessed and the level of expertise required. ... number of factors, including the location of the service and its overall aims. In principle ,the main activities of the service will be based around education and improving standards of sexual health...
Ngày tải lên: 14/02/2014, 21:20
Báo cáo khoa học: Limited mutagenesis increases the stability of human carboxypeptidase U (TAFIa) and demonstrates the importance of CPU stability over proCPU concentration in down-regulating fibrinolysis doc
... and using the same protocol as used in the primary screening described above. Determination of the half-life (T1/2) of CPU’s activity The T1 ⁄ 2 of the activity of the best mutants secreted in the ... aggregation of the protein. This is further confirmed by the existence of a natural variant of CPU, where T347 is subsituted by an I. Although accentuating the hydrophobic character of the protein ... changes in the positioning of the propeptide, or, in other words, to see if the contact region between the catalytic domain and the prodomain was changed by the mutations, we also measured the residual...
Ngày tải lên: 07/03/2014, 12:20
MICROECONOMICSPrinciples and AnalysisFrank A. CowellSTICERD and Department of Economics London School of Economics December 2004.ii.ContentsContents List of Tables List of Figures Preface 1 Introduction 1.1 The rôle of microeconomic principles . potx
... in the analysis of game-theoretic models (chapter 10) –how one player responds to the actions of another on the assumption of a speci…c form of the rules of the game. We use the comparative statics ... given list of inputs z. The particular properties of the function incorporate our assumptions about the “facts of life” concerning the production technology of the …rm. xviii LIST OF FIGURES 9.7 The ... begin with each of the two main economic actors the …rm and the household –and their re lationships to the market. Understanding how these relationships work is the key to a lot of other interesting...
Ngày tải lên: 08/03/2014, 10:20
Báo cáo khoa học: The involvement of human ribonucleases H1 and H2 in the variation of response of cells to antisense phosphorothioate oligonucleotides pot
... to analyze the effects of ODNs delivered by electroporation. The data of the 15PC3 cells are compatible with the hypothesis that RNase H2 can play a role in the in vivo response of c ells. They a re the ... hese gels, as the ODN h ybridizes to the center of the input target RNA. The asterisk indicates the input target RNA; the arrow indicates the digested product bands. The amount of digested product ... mediated cleavage of target mRNA. The presence of two mRNA species, as well as a variation in the cellular l ocalization comp licates the interpretation of the role of RNase H2 (Table 3). The main 1.2-kb...
Ngày tải lên: 08/03/2014, 10:20
Bringing the Hidden Giants to the Footlight: the Role of Savings and Retail Banks in Increasing the Level of Access to Financial Services docx
... decided on the basis of the borrower’s investment need and their ability to repay. The amount of the first loan does not exceed US$ 750 and the borrowers can apply for a second loan of up to ... and the repayment capacity of their clients, a domain where they have a high level of expertise, while savings banks could make use of their front and back of ce systems for disbursing of ... channelling more of the remittances into the financial system and intermediating the flow of the resources, savings banks contribute to leveraging the positive impact of these transfers. In...
Ngày tải lên: 15/03/2014, 10:20
Surfing the waves of globalization - Asia and financial lobalization in the context of the trilemma
... TIỂU LUẬN TÀI CHÍNH QUỐC TẾ ĐỀ TÀI: SURFING THE WAVES OF GLOBALIZATION: ASIA AND FINANCIAL LOBALIZATION IN THE CONTEXT OF THE TRILEMMA + GVHD : Ts Nguyễn Khắc Quốc Bảo + Nhóm ... cho nền kinh tế đóng theo đuổi chính sách tỷ giá cố định. Vì vậy, đối với các nước có nền kinh tế đóng có mức độ nắm giữ IR cao ( cao hơn ngưỡng 15-16% GDP), tốt cho việc theo đuổi chính sách ... trung vào việc theo đuổi tỷ giá hoái đoái cố định. Đối với nền kinh tế này thì biên động đầu tư ít quan trọng nhưng nó làm quan trọng hơn mức độ nắm giữ IR cao. Thật là quan trong khi theo đuổi...
Ngày tải lên: 15/03/2014, 11:21
Báo cáo khóa học: The proteasome inhibitor, MG132, promotes the reprogramming of translation in C2C12 myoblasts and facilitates the association of hsp25 with the eIF4F complex pptx
... ole in the migration of endothelial cells and i n recovery of cells from wounding [40]. In a variety of cells, in a ddition to the induction of hsp25 and aB-crystallin expression, inhibition of the ... investigation into the regulation of protein synthesis in mammalian cells, we have investigated the e ffects of inhibition of the p roteasome o n the localiza- tion and integrity of eIF4G in C2C12 ... myoblasts, inhibition of the proteasome with MG132 or lactacystin (data n ot shown) promotes a transient, incomplete inhibition of the rate of protein synthesis, followed by a re-programming of the t ranslational...
Ngày tải lên: 23/03/2014, 12:20