verifying and refining the interaction design

... have the main objective of developing their career and growth The organization and its managers are, therefore, required to be able to realize the key employees’ career desire and provide them the ... in the context of globalization and integration at the current They can only deliver their knowledge and working skills that they have been applying and experiencing in their works during the ... old They have been working for the company for more than years They have expressed their loyalty and commitment to the development of the company in the future They also participated in the above-mentioned...

Ngày tải lên: 14/10/2014, 01:10

... headquarters, design and wafer fabrication facilities in Chandler and Tempe, Arizona; Gresham, Oregon and design centers in California and India The Company’s quality system processes and procedures ... here, with the goal to be only at half of the input range of the MCP3909 ADC when the input current of the meter is at IMAX This leaves much room for over-current and greatly reduces the chance ... of the most secure families of its kind on the market today, when used in the intended manner and under normal conditions • There are dishonest and possibly illegal methods used to breach the...

Ngày tải lên: 11/01/2016, 16:46

... for the binding of 4.40 kcal mol1 of the next minimum i The next minimum j repeats some of the prior interactions, including the donation from both the CO p and p* orbitals into s*(SS) A new interaction ... general statement about the relative strengths of SHãããO and NHãããS On the other hand, it would be fair to claim that the CHãããO H-bond is weaker than either of the other two Note, however, that ... noncovalent interactions, but the E(2) values of all of them are only around 0.52 kcal mol1 The comparison of the complexes of NMA with CH3SH and CH3SCH3 indicates that the loss of the possibility...

Ngày tải lên: 16/12/2012, 15:21

... within the class structure These mediated class loca- Interaction of class and gender 123 tions affect both the gender interests of men and women ± the interests they have by virtue of the speci®c ... accepts this way of understanding the explanatory project of class analysis, then the central task is to sort out for speci®c explananda the forms of interaction between class and gender as causal ... monogamian marriage, and the ®rst class oppression with the of the female sex by the male '' Gerda Lerner (1986) elaborates a rather different argument about the con¯uence of class and gender in early...

Ngày tải lên: 01/11/2013, 07:20

... responsibility for and participation in the Public Internet Monitor Project the design of the gateway as well as the physical design and placement of the monitors Among the questions raised during the evaluation ... with Computer Science in the context of the work to be performed, the types of problems to be solved, and the types ofsystems to be designed and managed, and the way the technology is employed ... redefine the concept of design and present alternative understandings and interpretations? My thesis attempt to explore these questions; at the same time, I also try to formulate the arguments The...

Ngày tải lên: 04/11/2013, 20:15

... Protection and Security Service Integration Design for the Next Generation WAN Edge v2.0 38 OL-11727-01 Design and Implementation iACL and Logging on the Cisco 7304 and the 7301 Platforms On the Cisco ... processes” the iACL; once on the cipher text packet and then again on the clear text packet The line in the iACL that permits the encapsulating mGRE tunnel (which is sourced and destined to and from ... the NGWAN edge gear The goal of this section is to expand on the concepts in Design Overview, page and provide the detail needed for the solution administrator to understand and implement each...

Ngày tải lên: 24/01/2014, 10:20

... book and trying out the examples will lead you to design your own iOS apps, consult with larger design teams on mobile interface and user experience goals, and teach others how to design and format ... with the introduction of its iOS devices Rather, when introducing the iPhone in 2007, they simply added back a few of the key features they had taken away when they made the enormous leap from the ... But with the advent of the iPad and then the iPhone 4, things got really interesting with the app icon because each of these devices has a resolution that is different from the iPod touch and earlier...

Ngày tải lên: 12/02/2014, 20:20

... XL10 and the frame and the identity of the cloned fragment verified by sequencing The construct with the N-terminal portion of PPI1 has been previously described [22] The DNA fragment coding for the ... H+-ATPase in the PM and stimulate its activity [22] However, other parts of the protein may be important for regulation of the interaction As the entire PPI1 protein was difficult to handle due to ... H+-ATPase in the PM and stimulate its activity [22], suggested that the site of interaction with the PM H+-ATPase was localized in the N-terminus of PPI1 To further characterize the biological...

Ngày tải lên: 19/02/2014, 07:20

... positions 424 and 427 not mimic phosphorylated serine motifs important for the interaction between 14-3-3 and ExoS Therefore, this interaction is more complex and must occur in another way, whereby ... substitutions of the aspartic acid residues at positions 424 and 427 of the ExoS binding site for 14-3-3 These substitutions did not alter the ExoS)14-3-3 interaction under the conditions tested ... show that the leucine residue at position 428 is necessary for both the ADP-ribosylation activity and the cytotoxic action of ExoS in vivo Result and discussion Acidic residues within the 14-3-3...

Ngày tải lên: 19/02/2014, 08:20

... amino acid and the introduced aspartic residue at position 149 On the other hand, as agmatine lacks the a-carboxyl group, there would be no impediment for its binding and hydrolysis by the Asn149Asp ... consequence of the mutagenic replacements Effects of the His120Asn and His145Asn mutations on the affinity of metal binding to arginase II To further examine the effects of the His120fiAsn and His145fiAsn ... Mn2+A in arginase I and Mn2+B in arginase II Because ligands to the metal ions are strictly conserved in these enzymes, the difference would reside in the length of the ligand– metal separations...

Ngày tải lên: 20/02/2014, 02:21

... cyanobacteria at the time of chloroplast origin had poorly defined interactions between Cyt f and plastocyanin and/ or plastocyanin and photosystem I, and subsequently the nature of the interactions in the ... in [1] and in this paper) Although the curves are shallow, making extrapolation more difficult, and the number of datapoints is smaller than in the case of the interaction between Cyt f and plastocyanin ... [7] and Table in this paper) In what follows we summarize the expected contributions of binding and electron transfer to DHà and DSà and estimate their relative importance in the light of the...

Ngày tải lên: 21/02/2014, 01:21

... with the difference in the circulating concentrations of Gamide and transferrin In the present study, we explored further the interaction between Gamide and transferrin, and characterized the interaction ... ApoTf into the BIAcore channel to determine whether the ferric ions were required for the interaction between gastrins and ApoTf In the presence of EDTA, no interaction between ApoTf and either Gamide ... binding Thus, the lack of interaction between ApoTf and the E8–10A peptide suggests that either some or all of Glu8, Glu9 and Glu10 are involved in the interaction with ApoTf Alternatively, these results...

Ngày tải lên: 07/03/2014, 02:20

... of the complex The mutation could also affect the binding of the ISP to the bc1 complex and distort the Qo site Our data showed that, in the mutant, the bc1 activity was severely decreased The ... ISP and the extramembranous cd2 helix of cytochrome b are important for maintaining the structure of the hinge region and, by consequence, the movement of the headgroup and the integrity of the ... enzyme with their ISP in different conformations The mutation G167E could distort the hinge region of the ISP and hinder the movement of the headgroup Mutations in the hinge region of the ISP, which...

Ngày tải lên: 07/03/2014, 15:20

... proteins to the cytosol Here we confirm and extend earlier studies of these AAA-peroxins and give a further detailed functional analysis of their cassette structure and interaction The interaction ... the binding sites of these two AAA-proteins to their different protein regions and elucidated the importance of ATP-binding to the two AAA-cassettes of Pex1p and Pex6p for their interaction The ... an activation of the reporter gene and thus is sufficient to maintain the interaction with Pex1p These findings demonstrate the importance of the first AAAcassette together with the N-terminal region...

Ngày tải lên: 07/03/2014, 16:20

... 3A) and ATP (Fig 3B) in the absence and presence of curcumin, using the coupled enzyme assay In Fig 3A, the half-maximal activation of the ATPase by Ca2þ was measured in the absence of and in the ... side of the membrane While in the E2 form the Ca2þ binding sites have translocated across the membrane to the luminal side and are of low affinity Furthermore, in the E1 conformational state, the ... contact in the absence of ATP, curcumin is then able to bind to the ATPase (possibly at the hinge region) locking the two domains together and therefore precluding ATP binding (i.e inhibiting the ATPase...

Ngày tải lên: 08/03/2014, 23:20

... testimony to the ingenuity of the early designers of the Internet architecture, and the fact that by and large, their original design has been maintained and has guided the development of the network ... arguably due to the fact that network designers admittedly never had—nor will they ever have—a clear idea about all the ways the network can and will be used in the future On the other hand, the network’s ... requirements, first and foremost among them the robustness criterion, has to a large degree been responsible for shaping the architectural model and the design of the protocols (standards governing the exchange...

Ngày tải lên: 15/03/2014, 22:20

... sorting, and (c) understand the role of the EXXXLL motif in GLUT8 sorting The data provide evidence that endogenous GLUT8 co-localizes with the lysosomal proteins LAMP1 and LAMP2 in spermatocytes and ... [24] We therefore analysed the localization of GLUT8 and the GLUT8-LL ⁄ AA mutant in cells that lack specific subunits of AP3 The mouse mutants mocha and pearl are deficient in the AP3 d [25] and b3A ... However, the findings have been contradictory with regard to localization of the endogenous GLUT8 in testis, the nature of its sorting, and the interaction of its Nterminal dileucine motif with the...

Ngày tải lên: 16/03/2014, 02:20

... to the seller is equal to the cash ¯ow generated The average buy and sell prices for the 50% ticket were $29.17 and $45.43, respectively, and for the 80% ticket, they were $48.78 and $71.90 These ... values were determined from Eq The prices used in the computations are the sales over the period and prices are set equal to the Value trends If the demands and prices of the products competing within ... Wu: On the valuation of goods and selection of the best design alternative The fact that the values determined for the intercepts are close to the respective EEVs of the tickets supports the use...

Ngày tải lên: 16/03/2014, 11:20

... on the combination of the principles that, on the one hand, the market of reference for the territorial exercise of national intellectual property is the entire Internal Market, and, on the other, ... of the organization and the licensing practice of the pool.55 Surprisingly enough, however, at this level the Commission tends to ignore the link between the exclusivity and standardization, and ... not the equipment but the technology supplied by the principal which constitutes the essence of the contract However, the essence of sub-contracting is neither the supply of equipment nor the...

Ngày tải lên: 16/03/2014, 12:20

... (Life The ligand-dependent interaction between AR NTD and AR LBD, N/C interaction, was studied in yeast and mammalian in vivo protein interaction systems, and in Ó FEBS 2002 Interaction between androgen ... of the LBD, respectively (K720 and E897 in AR) [35–37] AR K720 and E897 are both involved in the ligand–dependent interaction between AR LBD and the coactivator TIF2 [9,11,15] However, in the ... by interaction with the charged clamp [5,36,37] The first and last leucine residue in the LxxLL motif enter the hydrophobic cleft in the LBD, and directly contact amino acid residues within the...

Ngày tải lên: 17/03/2014, 10:20