the sum of cubes of 1 to 100 is

... of Mls1p to peroxisomes is advantageous for growth on oleic acid Two steps of the glyoxylate cycle take place in the cytosol: the splitting of isocitrate into succinate a nd glyoxylate, and the ... con®rming the speci®city of the antibody. Application of the an tibody to thin se ctions of wild-type cells grown on oleic acid medium Fig. 1. SKL is required to direct Mls1p to the peroxisomes ... dilutions of cell cultures (BJ19 91, KM12, KM13) to this medium showed that the mls1D mutant was unable to form a clear zone (Fig. 4A). On the other hand, despite representing a strictly cytosolic...

Ngày tải lên: 22/02/2014, 04:20

... human lamin B recep- tor sequences. Microbiology 14 5, 14 43 14 51. 18 . Simos, G., Maison, C. & G eorgatos, S.D. (19 96) Characterization of p18, a component of the lamin B receptor complex and a ... through the RS region of LBR to linker DNA of chromatin s eems to b e predominant. Then, the binding is supported by the interaction of the NM region and a protein(s ) other t han HP1 on sperm ... on the addition of a high concentration of a truncated recombinant LAP2 protein to the cell-free Xenopus egg extract system [10 ]. Further analysis of the regulation mechanism for the binding of...

Ngày tải lên: 22/02/2014, 04:20

Ngày tải lên: 13/08/2014, 05:21

Ngày tải lên: 13/08/2014, 09:20

... life. Discuss with your partner about this. 3. Shopping is a waste of time and money. To what extend do you agree with this statement? 4. Discuss the advantages and disadvantages of tourism. 5. ... space at the furniture superstore. If you ever decide to visit Britain, you will need to know some of the basic rules of the sport. First of all, remember that you only need one person to make ... discuss the following topic (Students picked up one among the topics given) 1. The best way to travel is by bicycle. To what extend do you agree with this statement? 2. Money is the most important...

Ngày tải lên: 07/11/2012, 14:58

... closed without the decision to initiate any other phases. For example, the project is completed or the risk is deemed too great for the project to be allowed to continue. A Guide to the Project ... risk management on a project. It consists of the Risk Management Planning, Risk Identification, Qualitative Risk Analysis, Quantitative Risk Analysis, Risk Response Planning, and Risk Monitoring ... Management? 8 1. 4 The PMBOK ® GUIDE Structure 9 1. 5 Areas of Expertise 12 1. 6 Project Management Context 16 Project Life Cycle and Organization 19 2 .1 The Project Life Cycle 19 2.2...

Ngày tải lên: 15/12/2013, 13:15

... 8 .1, 1% BSA or 0.2% Triton X -10 0. The final concentrations of uPA was 0 .12 5 mg·mL 21 (2 .15 nM), of PAI -1 in the range 0 10 mg·mL 21 (0 18 5 nM), and of vitronectin in the range 0 15 mg·mL 21 (0–200 ... 87 .1 ^ 22.2 (20) 11 3.7 ^ 28.0 (10 ) † 1. 3 K335A S/G/Q 11 4.9 ^ 21. 5 (5) 12 9.5 ^ 21. 1 (3) 1. 1 S53A A/G/Q 71. 6 ^ 9.4 (8) 84.9 ^ 5.9 (3) 1. 2 S53A/K335A A/G/Q 84.3 ^ 15 .5 (4) 91. 0 ^ 13 .3 (3) 1. 1 G56A ... prior to determination of the remaining LMM-uPA activity with S-2444. Inset: portions of 3 mg of the PAI -1 variants were diluted in 0 .1 M Tris, 0.2% Triton X -10 0, pH 8 .1 to 0 .16 mg·mL 21 followed...

Ngày tải lên: 22/02/2014, 07:20

... 3505–3 511 ª 2005 FEBS 3 511 HYPOTHESIS Death inducer obliterator protein 1 in the context of DNA regulation Sequence analyses of distant homologues point to a novel functional role Ana M. Rojas 1, 2 , ... function for the DIDO1 long isoform (Figs 3 and S2). It is the second domain of the elonga- tion factor, TFSII [15 ], that stimulates RNA poly- merase II to transcribe through regions of DNA. The structure ... contains the CXXC signature between the two domains, probably as a result of recombination processes; this signature is missing in DIDO1 and SPP1. The absence of the CXXC signa- ture distinguishes...

Ngày tải lên: 07/03/2014, 21:20

... apoptosis at 10 0 n M , and high levels of apoptosis were measured at concentra- tions of 1 n M and 10 n M . Ala31Leu60-IGF-I failed to prevent serum deprivation-induced apoptosis at 1 n M and 10 ... directly related to ability to b ind to the IGF1R. Previously we have expressed a recombinant f orm o f the human IGF1R by fusing the cDNA encoding the receptor ectodomain (resi- dues 1 944) to the cDNA of the ... and access to the receptor. Having established the re lative binding af®nities of IGF-I, IGF-II and the 14 analogues for rhIGF1R, we related these to their abilities to prevent apoptosis. IGFs...

Ngày tải lên: 08/03/2014, 22:20

... Manb1fi2Mana1fi2 1. 9 21 5 .13 8 4.256 Manb1fi2Manb1fi2Mana1fi2 13 .6 22 4. 915 4.4 01 Manb1fi2Manb1fi2Manb1fi2Mana1fi2 1. 9 23 4. 918 4 .14 7 Manb1fi2Manb1fi2Manb1fi2Mana1fi2 1. 9 24 4.844 4.247 Manb1fi2Manb1fi2Manb1fi2Mana1fi2 ... a1fi6Mana1fi6Mana1fi6Mana1fi6 ›2 Mana1 11 5 .10 4 4.029 a1fi6Mana1fi6Mana1fi6Mana1fi6 ›2 ›2 ›2 Mana1 12 5.093 3.997 a1fi6Mana1fi6Mana1fi6Mana1fi6 ›2 a1fi2Mana1 18 .9 13 5.074 4.008 a1fi6Mana1fi6Mana1fi6Mana1fi6 ›2 ›2 ›2 a1fi2Mana1 14 ... Mana1fi2Mana1fi2 2.8 6 5.2 61 4.087 a1fi2Mana1fi2Mana1fi20 7 5 .15 2 4 .12 6 b1fi2Mana1fi2Mana1fi2 15 .5 8 5.233 4.096 a1fi3Mana1fi2Mana1fi2Mana1fi2 ›6 Mana1 0 9 5 .13 0 4.065 Mana1fi30 10 5 .12 1 4. 017 a1fi6Mana1fi6Mana1fi6Mana1fi6 ›2 Mana1 11 ...

Ngày tải lên: 17/03/2014, 03:20

... LY200729 01, L200629 01, 032 912 , 200529 01) , the Youth Science Foundation of Shandong Province (Nos 2005BS 11 010 ), the Natural Science Foundation of Shandong Province (Nos Q2006F05, Y2005F 11) , the ... by the occurrence of some tidy nanoparticles, are as shown in figure 3e. The effect of SnCl 4 addition on the morphology of α- Fe 2 O 3 is obvious, but what is the existence of Sn? it is ... using a JEOL JEM- 210 0F field emission transmis- sion electron microscope. 3. Results and discussion Figure 1 shows the typical XRD pattern of the product. All the reflections of the XRD pattern...

Ngày tải lên: 19/03/2014, 16:48

... 35 6 * Sp3 Sp1/3 * 12 612 12 25 256 9 10 111 2 15 13 16 17 14 12 3 64785 18 19 20 21 22 23 10 0 24 25 26 25 50 25 50 10 0 10 0 5 010 0 10 0 50 10 0 10 0 AB CD Fig. 6. AbH-J-J promoter P1 elements homologous to the Sp1 ... concentration of 0 .12 5 m. The cells were then suspended in 1. 5 mL of lysis buffer (1% SDS, 10 mm EDTA, and 50 mm Tris ⁄ Cl, pH 8 .1) plus protease inhibitors (1 lgÆmL )1 pepstatin A, 1 lgÆmL )1 leupeptin, 1 ... promoter; this finding is of interest, when related to the different tissue specificities of these two promoters [1, 13 ,16 ]. Identification of GC boxes within the ) 512 ⁄ +33 AbH-J-J P1 promoter region Sequence...

Ngày tải lên: 23/03/2014, 07:20

... are close enough to hydrogen-bond to the distal ligand. We have proposed that, if the amide nitrogen of Gly143 is the proton donor hydrogen-bonded to the iron-bound oxygen of the ferric hydroperoxide, ... stabilize the negatively charged oxygen and facilitate the electrophilic addition of the terminaloxygentothea-methene bridge [11 ]. The recent findings by Liu et al. [17 ] that Gly143 mutants, all of which have ... additions of 0 (–), 1. 1, 1. 7, 2.6 (ÆÆÆ), and 3.3 eq (spectrum a, - - -) of NADPH, in the presence of NADPH-cytochrome P450 reductase, to the synthetic verdohaem complexed with rHO -1. (B) The spectrum...

Ngày tải lên: 23/03/2014, 21:20

... spectrometer; the remainder of the flow was diverted to the UV detector ( 215 nm monitored). The flow split was monitored by using a Humonics Optiflow 10 00 flowmeter (Sigma) coupled to the outflow of the UV ... DESCRCEGLRMM(20– 31) or MDESCRCEGLRM (19 –30) ESCRCEGLRMM( 21 31) MSECCEQLEG(9 18 ) or SECCEQLEGM (10 19 ) 3 31. 75 212 0.0 19 76.0 2033.2 211 9.9 19 76.0 2032 .1 AENIPSRCNLSPMRCPMGGS(54–73) AENIPSRCNLSPMRCPMG(54– 71) AENIPSRCNLSPMRCPMGG(54–72) 4 ... conditions 1 2 3 4 5 6 7 -20 0 20 40 60 80 10 0 12 0 14 0 0 5 10 15 20 25 30 35 40 45 50 55 Time (min) Absorbance 215 nm -10 -5 0 5 10 15 20 25 30 0 5 10 15 20 25 30 35 40 45 50 55 Time (min) Absorbance 215 ...

Ngày tải lên: 30/03/2014, 15:20

... Hemingway 15 2 How to make great grilled chicken 15 3 How to learn to fly fish 15 5 How to prevent identity theft 15 8 How to compete at altitude 16 0 How to watch the Tour de France 16 1 How to get rid of ... speaking 18 3 How to save the Earth 18 4 How to turn a mountain back into a molehill 18 7 How to get rid of all those frequent flyer miles 18 8 How to live to 10 0 18 9 How to run a democracy 19 2 How to ... a securities for this company. banana peel and the other in Chapter 11 . Disregard our exuberance. 5 text.p65 1/ 29/2003, 3:32 PM18 11 How to travel to space 11 Hey, if a codger like former Senator John...

Ngày tải lên: 03/06/2014, 01:09

... Sacrifice of Happiness? 10 7 63. Love, Self-Concern, and Concern for Others 10 9 64. Eudaemonism and Concern for Others 11 1 6. Aristotle: Happiness 11 4 65. Interpreting Aristotle 11 4 66. Aristotle’s ... describe these criticisms as a series of nails in the coffin of Aristotelian naturalism. According to one view, the criticisms are so cogent that enlightened moralists are right to discard the Aristotelian ... trying to reconcile Aristotle with Kant. If we try to explore the history of reflexion on Aristotelian naturalism, we may be able to see whether Sidgwick’s view is right. To clarify some of the issues...

Ngày tải lên: 11/06/2014, 10:28

... PEP -1- SOD1-His or PEP -1- CAT-His had the similar enzymatic activities as the wild type SOD1 or CAT. Transduction of PEP -1- SOD1 or PEP -1- CAT into H9c2 cell The subcellular transduction of PEP -1- SOD1 ... 9:73 http://www.translational-medicine.com/content/9 /1/ 73 Page 6 of 11 Figure 3 Effect of PEP -1- SOD1 and PEP -1- CAT on LDH level and apoptosis rate. (A) Effect of PEP -1- SOD1 and PEP -1- CAT on LDH level. *P < 0. 01 vs. control (CTL) ... expression was further increased by the treatment with both PEP -1- Figure 1 Transduction of purified PEP -1- SOD1 or PEP -1- CAT into H9c2 cells. A: purific ation of PEP -1- SOD1-His and PEP -1- CAT-His fusion proteins....

Ngày tải lên: 18/06/2014, 19:20

Ngày tải lên: 20/06/2014, 23:20

Ngày tải lên: 01/07/2014, 14:20