the source of the nile is in abyssinia
Tài liệu THE DISCOVERY OF THE SOURCE OF THE NILE docx
... scared by the interminable singing, shouting, bell-jingling, horn-blowing, and other such merry noises of the moving caravan, could be seen disappearing in the distance. Leaving the park, ... be bridged by throwing a tree across it in the wet one. Rising in the Usagara hills to the west of the hog-backed Mkambaku, this branch intersects the province of Ukhutu in the centre, and circles ... consideration is the power held by the magician (Mganga), who rules the minds of the kings as did the old popes of Europe. They, indeed, are a curse to the traveller; for if it suits their inclinations...
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The Discovery of the Source of the Nile docx
... crossing the road to the northward, drains these lands to the Malagarazi river, and thence into the Tanganyika lake. Thence, having spent the night in the jungle, we next morning pushed into the ... be their chief, answerable for the actions of the whole. Being in the position of "boots" to the camp, the tending of goats fell to their lot. Three goats were missing this evening, ... XIXChapter XX The of the Source of the Nile, by SpekeProject Gutenberg's Etext The of the Source of the Nile, by Speke Copyright laws are changing all over the world, be sure to check the laws...
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Tài liệu Báo cáo khoa học: Glucuronate, the precursor of vitamin C, is directly formed from UDP-glucuronate in liver pptx
... the formation of glucuronate. Interestingly, vitamin C for-mation is induced in Gunn rats by phenobarbital [8],an inducer of UGT2s, which is indirect evidence for the involvement of members of the UGT2 ... to the ability of this nucleotide to stimulate UDP-glucuronate in ux into microsomes [11]. This involvesconversion of UDP-glucuronate to UMP in the lumen of the vesicles and exchange of the ... UDPGlcNAcindicates that this enzyme is present in the same type of vesicles as UDP-glucuronosyltransferases.Further analogy between the two types of enzymes is found in the similarity of the effect of detergents.All...
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Báo cáo khoa học: Arabidopsis thaliana CYP77A4 is the first cytochrome P450 able to catalyze the epoxidation of free fatty acids in plants potx
... into the cutin. In this context, it is interesting to note thatinhibition studies allowed LeQueu et al. [49] to demon-strate the involvement of a peroxygenase in the forma-tion of cutin of corn. The ... regioselectivity of CYP77A4 wasdetermined on the basis of the peak area of each metabolitedetected by GC.Metabolites of linoleic acidFor the analysis of the products generated by recombinantCYP77A4 on incubation ... are given in Fig. S2. The regioselectivity of CYP77A4 was determined on the basis of the peak area of each metabolite detected by GC.Metabolites of oleic acidFor the analysis of the products...
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Báo cáo khoa học: ATP-binding domain of heat shock protein 70 is essential for its effects on the inhibition of the release of the second mitochondria-derived activator of caspase and apoptosis in C2C12 cells potx
... the role of HSP70 in the inhi-bition of the release of Smac and apoptosis. The role of the ATP-binding domain of HSP70 in the prevention of the release of Smac andapoptosis after exposure to ... eliminating inhibition of caspases by inhibitor of apoptosis protein (IAP) and is known to be a new andimportant regulator of apoptosis in a variety of cancercells. The evidence obtained in ... H2O2-induced apoptosis in transfectedC2C12 cells. Furthermore, there was no direct interac-tion between HSP70 and Smac proteins, and the ATP-binding domain of HSP70, rather than the pep-tide-binding...
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Báo cáo khoa học: Transcriptional regulation of the desferrioxamine gene cluster of Streptomyces coelicolor is mediated by binding of DmdR1 to an iron box in the promoter of the desA gene doc
... for the treatment of iron overload duringmetabolic alterations in humans. Initial work on the biosynthesis of desferrioxamine B in S. pilosus indica-ted that the first step in the desferrioxamine ... containing the desA coding regionwas cloned into the pBluescript SK EcoRV site. As the DdesA mutant is apramycin resistant, the kanamycinresistance marker was cloned into an XbaI site of the ... box), explaining the regulation of desAexpression by binding of DmdR1 to the iron box. The same overlapping was found in S. pilosus.DmdR1 binds to the promoter region of desABCD in both S....
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Báo cáo khoa học: Oxidative stress is involved in the permeabilization of the inner membrane of brain mitochondria exposed to hypoxia/reoxygenation and low micromolar Ca2+ Lorenz Schild1 and Georg Reiser2 doc
... to the induction of oxidative stress during ischemia ⁄ reperfusion in brain.There is a growing body of information concerning the mechanism of ROS generation by the respiratorychain in mitochondria. ... ADP inhibitsopening of the mPTP by occupying binding siteslocated in the inner and outer mitochondrial mem-brane [39,40]. The binding of ADP stabilizes the matrix conformation of the adenine ... presence of theseelectron donors. This is of relevance in brain, because in this tissue glucose is metabolized providing the NADH-yielding substrate pyruvate. Under these con-ditions, some succinate...
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Báo cáo Y học: The role of the second binding loop of the cysteine protease inhibitor, cystatin A (stefin A), in stabilizing complexes with target proteases is exerted predominantly by Leu73 pdf
... Search FixingÕ of the side chains within the Leu73–Asn77 segment in the second binding loop of cystatin A. After each of these steps, the conformation of the second binding loop in the complex ... the inhibition of papainand most likely also of cathepsin L. The side chains of Leu73 and Pro74 jointly contribute 45% of the totalunitary free energy of binding of cystatin A to cathepsin ... B,demonstrating a major role of the second binding loop of cystatin A in the inhibition of this enzyme. Pro74 may bedirectly involved in the interaction with cathepsin B byproviding hydrophobic interactions...
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The Duality of Memory and Communication in the Implementation of a Multiprocessor Operating System
... notice and the title of the publication andits date appear, and notice is given that copying is by permission of the Association of Computing Machinery.To copy otherwise, or to republish, requires ... than in the inheritance case in that no sharing map is involved; an attempt to vm_write one mapping of the memory object would merely replace that mapping, rather thanreflecting it in other ... only in the organization of distributed and parallelapplications, but in the implementation of the operating system kernel itself. Mach uses memory-mappingtechniques to make the passing of large...
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In the Shadow of the Glen
... and the mists again, and they rolling up the bog, and hearing nothing but the wind crying out in the bits of broken trees were left from the great storm, and the streams roaring with the rain. ... stitching one of the tags in his coat, saying the "De Profundis" under his breath. In an instant the sheet is drawn slowly down, and Dan Burke looks out. The Tramp moves uneasily, then ... passing below on a dark night the like of this night, and the sheep were lying under the ditch and every one of them coughing, and choking, like an old man, with the great rain and the fog. Then...
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