the role of the coagulation system in preterm parturition

... (for the purpose of splicing of yarn) Use of Compressed Air in Textile Industry  Stacking Device  Printing machines  Thread Detector  Sewing Machine Applications  Texturising  System Cooling ... following Compressed air powered pneumatic systems are used:  Spinning machine (for control purpose through valves and cylinders)  Loom Jet Weaving (for the insertion of weft)  Winding machine ... consumption points (machines) The air receiver helps also in cooling of air and this facilitates removal of much of the moisture in the air which is harmful for the pneumatic system Air-dryer...

Ngày tải lên: 22/07/2015, 21:53

... unique Therefore, the study of the cross-talk between cancer cells and the immune system must be analyzed in the context of the organ in which the tumor exists and the type of cells that the tumor ... by the histologically defined layers of the skin However, this can be inaccurate as the thickness of the different layers of the skin can vary between individuals The Breslow’s thickness is the ... to TAMs in other parts of the tumor [8,30] In summary, inflammation and the immune system play critical roles in both tumor suppression and tumor progression Understanding the complex interactions...

Ngày tải lên: 10/09/2015, 15:50

... is the number of melanoma cells at the end of the experiment, N is the number of melanoma cells at the onset of the experiment, k is the fraction of proliferating cells, t is the duration of the ... is the number of melanoma cells at the end of the experiment, N is the number of melanoma cells at the onset of the experiment, k is the fraction of proliferating cells, t is the duration of the ... is the ratio of Dct expression in the lungs of control vs PMNMDSC-depleted mice, k c is the fraction of proliferating cells in the lungs of control mice and k d is the fraction of proliferating...

Ngày tải lên: 10/09/2015, 15:50

... achievements in the sphere of Microloans In 2000-2002:  banks increased the intensiveness and volumes of the small business financing;  reduced a minimal loan sum;  began to use flexible credit interest ... simplified the procedure of application examination and allowance of credits Last achievements in the sphere of Microloans (continued)  November 1999: Informal “Working group on microfinance policy” ... attracting resources from financial institutions reinvestments the National Business Incubator Association of Russia Founded in 1997 by 22 Russian business incubators and SME support institutions...

Ngày tải lên: 24/10/2013, 03:15

... satisfactory in the evaluation of nodal status in this patient group Since the highly cellular tissue in reactive lymph nodes may also show increased intensity, the role of DWI and ADC in distinguishing ... tissue in the uterine cervix and endometrium In the uterine myometrium, the ADC value may play a limited role due to the large overlap between sarcomas and benign leiomyomas The role of DWI for the ... enhancing cervical cancer (arrow) The tumor invades the cervical stroma (arrowhead) c DWI with b = 1,000 s/mm2 shows a well-defined hyperintensity mass in the cervical area The shape of the uterine...

Ngày tải lên: 13/02/2014, 06:20

... Protein targeting to the microsomes requires the cotranslational insertion of the newly synthesized protein into the microsomal membrane, where the N-terminal hydrophobic signal sequence of the ... mitochondria-targeting signal in the yeast system Mitochondrial localization of intact CYP2E1 in yeast cells Because of the existing ambiguity in the literature on the nature and extent of CYP2E1 import into ... consistent with the model suggesting a transmembrane topology of CYPs with a single N-terminal membrane anchor and most of the remaining protein exposed to the cytosolic side [15,17,30,31] The intramitochondrial...

Ngày tải lên: 18/02/2014, 16:20

... lysine reduces the probability of forming the fully closed form of the protein The results obtained with the K22V/R120K double mutant protein point toward a central role of arginine 120 in the ... enthalpies of binding and stoichiometries were determined from the binding isotherm by fitting a : binding model to the data using the software provided by the manufacturer Results Reaction of fosfomycin ... chain of K22 participates in fosfomycin binding, thus providing a rationale for the loss of fosfomycin binding to the K22V and K22E mutant proteins However, two other positively charged amino...

Ngày tải lên: 19/02/2014, 13:20

... iron-peroxo intermediate [11] The sum of these ndings points at the involvement of more than one active oxidant in the diverse types of P450-catalyzed substrate processing [1215] The goal of the present ... reect ring opening of an epoxide intermediate at either of its two C-O bonds [219,220] The sum of these ndings strongly invokes the notion of oxygen activation during redox cycling of the diverse ... alterations in the environment can cause drastic changes in the reactivity of the active species [76] Further support in favour of the idea of the involvement of a high-valent iron-oxene in P450...

Ngày tải lên: 19/02/2014, 16:20

... (1992) Role of the antithrombin-binding pentasaccharide in heparin acceleration of antithrombinproteinase reactions Resolution of the antithrombin 4847 Control of the coagulation system by serpins ... these result in the irreversible inactivation (generally) of the serpins, and, in the case of the anticoagulant serpins, a lowering of the effective concentration of the serpins and therefore diseases ... combination of the changes in the structure of the RCL, allowing the interaction of residues on the RCL with subsites in the active site of fXa [16,17], and the exposure of a new exosite on the...

Ngày tải lên: 20/02/2014, 02:21

... Regional Learning Alliance – workforce development and training/collaborations with business and industry; meeting the training and education needs of businesses within 60 mile radius in Northern Allegheny ... $28,000 in average annual salary) Preserving Value Continuing education is important to preserving the market value of specialized education – particularly in professional fields Continuing education ... Shippensburg University Small Business Initiative in the Frehn Center for Management; offering information and assistance to individuals and groups planning to start a new business Best Practice Highlights...

Ngày tải lên: 21/02/2014, 01:20

... Amino–aromatic interactions in proteins FEBS Lett 203, 139–143 19 Chakrabarti, P & Samanta, U (1995) CH/, p interaction in the packing of the adenine ring in protein structures Advan Protein ... determined as part of the investigation into the shielding from solvent of the electrostatic interaction between Asp113 and His210 With increasing NaCl, the maximum activity decreased, while the ... deviation, the solvent ASA of the side-chain of His210 increased with the decrease in size of the side-chain at residue 169 (Table and Fig 3A) However, the ASAs of Asp113 and His57 remained constant...

Ngày tải lên: 21/02/2014, 03:20

... Ala219 of the catalytic site and His135 of the Mg2+ binding site The most striking result was the loss of the psychrophilic character of mutant W260K/A219N (as reflected by a threefold increase of the ... value in this temperature range is considerably lowered On the basis of the model, the behavior of the G261A variant can be interpreted in terms of constraints introduced by the Ala side chain The ... our incomplete understanding of the relation between enzyme properties and conformational flexibility limits the exploitation of the full potential of protein engineering in the redesign of psychrophilic...

Ngày tải lên: 22/02/2014, 04:20

... against a sequence between the N-terminal and the first transmembrane domain of the protein of the human and rat CB2 receptor The specificity of the CB1 and CB2 antibodies was described in McIntosh ... nonspecific interactions is supported by the observation that preabsorbing of the CB1 antibody with its corresponding blocking peptide eliminated almost all of the staining of these bands (Fig 3A) The ... marrow stem cells, are the most potent antigen-presenting cells of the immune system They play a central role in the initiation of primary immune response and in the enhancement of secondary immune...

Ngày tải lên: 22/02/2014, 07:20

... dissecting the role of the endocannabinoid system in physiology as well as in pathological processes The system incorporates the endocannabinoids, their synthetic and degradative enzymes, the endocannabinoid ... endothelial isoform of this enzyme are beneficial by, among other mechanisms, sustaining blood flow in the periphery of the ischemic brain On the other hand, under normal circumstances, stimulation of NMDA ... [42] The endocannabinoid system in cerebral ischemia The ‘dark side’ of CBs An independent line of research supports a contrasting, neurotoxic role for CB receptor activation in ischemia, a role...

Ngày tải lên: 07/03/2014, 03:20

... by the C domain of the initiation module of daptomycin That DptE and DptF are involved in the lipidation process of daptomycin was first shown by Miao et al [1] In their work, the daptomycin gene ... is GLDSV, indicating that this putative ACP domain is one of the few ACPs in which valine replaces isoleucine (I) or leucine (L) in the conserved sequence To determine whether DptF is the putative ... tryptophan of the nonribosomally synthesized peptide is necessary Here, we report the results of a steady-state kinetic analysis of DptE The aim of this kinetic study was to determine the specificity of...

Ngày tải lên: 07/03/2014, 04:20

... evaluate the OS-fitness of the clone, the ratio of the specific absorbance in the presence of 10 lgÆmL)1 HEL to that in the absence of HEL was taken as an index To analyze the effect of the type of each ... clarify the effect of the interface mutations on the antigenbinding affinity To investigate systematically this unsought relationship between the antigen-binding affinity of Fv and the VH ⁄ VL interaction ... antigen binding, this ‘increasing the affinity by increasing the VH ⁄ VL interaction’ might represent a mechanism of increasing Fv affinity This is also supported by the kinetic study of purified...

Ngày tải lên: 07/03/2014, 12:20

... Cardie, Vincent Ng, David Pierce, Chris Buckley Examining the role of statistical and linguistic knowledge sources in a general-knowledge que stion answering system In Proceedings of the 6th Applied ... hypernyms in the answer semantic form Step 3: The assessment of the similarities of dependencies In the third step, two classes of similar dependencies are considered, generating unications of the ... example, in the case of question Q209: Who invented the paper clip ?, the expected answer type is P ERSON and so is the subject of the verb invented , lexicalized as the nominalization inventor...

Ngày tải lên: 08/03/2014, 05:20

... change their brand attitude, may suggest an interesting implication for the new brand advertising strategy Instead of focusing on the content of the message which only emphasizes the benefits of the ... birthday This finding is just reverse of the finding of Belk (1973) Ruth, Brunel, Otnes (1999) classified categories of gift-giving into public occasion (i.e., Christmas, Chinese New Year), individual ... situational conditions of gift-giving may differ according to characteristics of the gift-giving occasion, whether the presentation of the gift is public, private, or anonymous, and whether the gift is...

Ngày tải lên: 14/03/2014, 14:20

... important for explaining wilt In the case of income, youth living in low-income households experience higher levels of wilt (45%) than youth living in either modest-income (35%) or high-income (23%) ... financing school Conley (2001) finds that a doubling of net worth results in an 8.3% increase in the probability of attending college Further, when net worth is included in the model, Black youth are ... youth Youth savings Youth were asked in 2002 whether they had a savings or bank account in their name If they had an account, they were also asked whether they were saving some of this money for...

Ngày tải lên: 15/03/2014, 10:20

... that the increase of Glc6P in the presence of S4048 was caused by the inhibition of Glc6P hydrolysis in the absence of detectable changes in glucose phosphorylation S4048 causes inactivation of ... [31], for evaluating the role of Glc6P, we determined the effect of different inhibitor concentrations on the Glc6P content and the rate of glycogen synthesis in hepatocytes incubated with 15 ... Harndahl et al ¨ levels through the interaction of glucokinase with binding proteins [5,6] The glucokinase regulatory protein (GKRP) is a specific inhibitor of glucokinase [5] and also a nuclear...

Ngày tải lên: 16/03/2014, 14:20