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the prime minister of japan beginning in 1941 was

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Báo cáo y học: "PKC and PKA Phosphorylation Affect the Subcellular Localization of Claudin-1 in Melanoma Cells"

Y học thưởng thức

... (CLDN1-NLS), there is increased expression of claudin-1 in the nucleus, but there are still large amounts of claudin-1 in the cytoplasm as well. B) All of the claudin-1 in the nucleus can be shuttled into ... expression of claudin-1 in the cytoplasm, with some nuclear expression of claudin-1. B) Treatment of these cells with PKA inhibitor results in nuclear translocation of claudin-1 in as little as 15 minutes, ... seeded onto the filters. The total volume on the top of the filter was adjusted to 800μL of serum free medium and 800μL of medium containing 20% fetal calf serum was placed in the lower well...
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Tài liệu Đề tài

Tài liệu Đề tài " The topological classification of minimal surfaces in R3 " pptx

Thạc sĩ - Cao học

... carried out independently of the other planes since the modified plane is contained in the union of the components of W that intersect P and when P intersects W ∈W, then noother plane in P intersects ... S into subslabs each of which contains a single end of F . Furthermore the addition of these planes toP gives a new collection satisfying Lemma 3.1.Proof. Here is the idea of the proof of the ... endpoints of k lie in the same boundary component of the samepair of pants. The arc of the boundary of the disk extending E lying in Γ defines acycle. As ∂E does not ever enter and leave a pair of...
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Tài liệu Báo cáo khoa học: "The Effect of Corpus Size in Combining Supervised and Unsupervised Training for Disambiguation" pdf

Báo cáo khoa học

... (without Collins) are given in the first lines. #is the size of the test set. The baselines are 73.1% (RC) and 51.4% (PP). The combined methodperforms better for sm all training sets. There is no ... giving rise to th e same set of dependen-cies (a piece of a tile of a roof of a house vs.a piece of a roof of a tile of a house) cannotbe distinguished. We believe that an invertedindex is the ... One of its vari-ants computes the estimate in question as the average of three b ackoffs. In addition to the maximum used here, testing other combina-tion strategies for the MI values in the...
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Tài liệu The high price of pain: the economic impact of persistent pain in Australia pdf

Tài liệu The high price of pain: the economic impact of persistent pain in Australia pdf

Cao đẳng - Đại học

... widespread pain at the outset. During the 12-year period of the study, 23 out of 214 individuals died (or 10.7%): 5 from the 73 individuals without chronic pain at the start of the study (or ... Cousins, 2004). Some of the changes in nerve functions thought to explain the abnormal sensations and sensitisation found in neuropathic pain include reduced descending inhibition in the CNS (the ... death was 72 (range 48–83) and 12 individuals out of 23 were females. Only one of the deceased individuals in the group with widespread pain had a known malignancy at the time of the initial...
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Tài liệu Báo cáo Y học: BIGH3 (TGFBI) Arg124 mutations influence the amyloid conversion of related peptides in vitro Implications in the BIGH3-linked corneal dystrophies pptx

Tài liệu Báo cáo Y học: BIGH3 (TGFBI) Arg124 mutations influence the amyloid conversion of related peptides in vitro Implications in the BIGH3-linked corneal dystrophies pptx

Báo cáo khoa học

... suggesting both these elements are of equal importance for the formation of amyloid from the C110)131 peptide.Role of the NH2-terminal sequence The role of the NH2-terminal sequence of the ... The second is the putative participation of local factors on the appearance of the disease. The TGFBIprotein, in addition to the cornea, is abundantly expressed in the skin. However, the clinical ... NH2-end of the peptides. In the same way, removing the CONH2-terminus of the peptides resulted in increasedamyloid fibril formation. This increase may be due to adirect inhibitory effect of this...
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Tài liệu Báo cáo khoa học: Characterization of the promoter for the mouse a3 integrin gene Involvement of the Ets-family of transcription factors in the promoter activity doc

Tài liệu Báo cáo khoa học: Characterization of the promoter for the mouse a3 integrin gene Involvement of the Ets-family of transcription factors in the promoter activity doc

Báo cáo khoa học

... binding factors. The introduction of mutation in one of the Ets-bindingsequences greatly decreased its promoter activity, suggestingthat the transcription of the a3 integrin gene in these cells ... includingEts, GATA, and MyoD/E-box binding factors. The introduction of mutation into one of the putative Ets-binding sequences suppressed the promoter activity. In addition, the specific binding ... assay (EMSA) using the Ets consensus site at )133As the involvement of the Ets consensus binding site at )133 in the promoter activity of the mouse a3 integrin gene was suggested by the luciferase...
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Occupational therapy interventions and physical activity interventions to promote the mental wellbeing of older people in primary care and residential care pdf

Occupational therapy interventions and physical activity interventions to promote the mental wellbeing of older people in primary care and residential care pdf

Sức khỏe người cao tuổi

... activities are intended as starting points; they should be tailored to meet the needs of the participants, as opposed to the activities dictating the group. The organisation of themes within the manual ... isolation (including older people from minority ethnic groups). 5. How does the effectiveness of interventions depend on the characteristics of those delivering the intervention, the involvement of ... around the home • keeping safe in the community • keeping safe in the home Personal circumstances • dealing with finance • social relationships and maintaining friendships • dining as an...
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Among the Great Masters of Music Scenes in the Lives of Famous Musicians pptx

Among the Great Masters of Music Scenes in the Lives of Famous Musicians pptx

Cao đẳng - Đại học

... dark against the sky, and what a sky! full of clear sun in the morning,full of pure heat all day, and bathed with ineffable tints in the cool of the evening, when the light lay low uponvinery ... recognised their valueby appointing Palestrina one of the singers of the papal choir, which was against the rules of the Church,married singers being debarred. Nor was the composer's voice ... nothing about them. After a long search, the boots were found; theywere hid under the trunk; the handkerchief lay in one of the boots; the coat in the box; and the waistcoat in the drawer of the...
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Báo cáo khoa học: Analysis of Lsm1p and Lsm8p domains in the cellular localization of Lsm complexes in budding yeast ppt

Báo cáo khoa học: Analysis of Lsm1p and Lsm8p domains in the cellular localization of Lsm complexes in budding yeast ppt

Báo cáo khoa học

... the latter, indicating that in the absence of an N-terminaldomain distinct localization is lacking. Finally, the Lsm1p Sm domain by itself (LsmDN1DCp) accumu-lates in both the nucleus and the ... carrying the N-terminus of one protein and the Sm domain of the other localize according to the N-terminal contri-bution: Lsm81DCp shows nuclear accumulation andLsm18DCp accumulates in cytoplasmic ... cytoplasmic foci understress conditions (Fig. 6A). Thus, in the absence of the C-terminal domain, the N-terminal domain, not the Sm domain, determines the subcellular localization. Bycontrast, LsmDN18p...
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WHO guidelines on the pharmacological treatment of persisting pain in children with medical illnesses docx

WHO guidelines on the pharmacological treatment of persisting pain in children with medical illnesses docx

Sức khỏe trẻ em

... providing basic pain care (66).Managingpainstartswithrecognizingandassessingpain.Therefore, planning pain assessment as an integral element of pain management at all levels of the health ... 33Box2.3Step-by-stepguidanceforadministeringandinterpretingaself-reportpainscale 34Box3.1Excludedmedicineforpainrelief 39Box3.2Formulations of morphinelisted in the WHO model list of essential medicines ... Breakthrough pain is characterized as a temporary increase in the severity of pain over and above the pre-existingbaselinepainlevel,e.g.ifachildistakingpainmedicinesandhasgoodpaincontrolwithastableanalgesicregimenandsuddenlydevelopsacuteexacerbation of pain.Itisusually of suddenonset,severe,and of shortduration.Anumber of episodes of breakthroughpaincanoccureachday.It...
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Báo cáo khoa học

... text.A.200A.400A.600A.800A.1000A.1200A.14000.860.880.900.920.94B.200B.400B.600B.800B.1000B.1200B.14000.860.880.900.920.940.860.880.900.920.94FC.200C.400C.600C.800C.1000C.1200C.14000.860.880.900.920.940.860.880.900.920.94FFigure 6: The graph of micro-average F -measureagainst the number of training sentences duringtext chunking (A: MHHMM, B: HHMM and C:HMM) The first finding is that the size of training datadramatically ... poor accuracy. In the text chunk-ing task the number of observation symbol relieson the number of part -of- speech tags contained in training data. Figure 6 plots the relationship of micro-average ... (PP IN) (NP NNP)) (O . ))where the model makes no use of the word infor-mation contained in the sentence.4.2 Grammar ParsingCreation of a parse tree involves describing lan-guage grammar in...
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Báo cáo khoa học: The subcellular organization of strictosidine biosynthesis in Catharanthus roseus epidermis highlights several trans-tonoplast translocations of intermediate metabolites docx

Báo cáo khoa học: The subcellular organization of strictosidine biosynthesis in Catharanthus roseus epidermis highlights several trans-tonoplast translocations of intermediate metabolites docx

Báo cáo khoa học

... in experiments testing the LAMT–TDC cross-interactions(Fig. 6 and Table 1). Interestingly, an analysis of the distribution of the BiFC complex in vivo revealed the restriction of the proteins to the cytosol ... of b-galactosidase activity allowing the confirmation of proteininteractions and the evaluation of the strength of proteininteractions.Table 1. Analysis of TDC and LAMT interaction using yeast two-hybrid ... on the subcellular organiza-tion and possible protein interaction of TDC, LAMTand SLS, comprising the three enzymatic steps preced-ing the biosynthesis of the first MIA strictosidinewithin the...
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Báo cáo khoa học: Modeling the Qo site of crop pathogens in Saccharomyces cerevisiae cytochrome b ppt

Báo cáo khoa học: Modeling the Qo site of crop pathogens in Saccharomyces cerevisiae cytochrome b ppt

Báo cáo khoa học

... affect the fitness of the cells. In combinationwith other factors, this could explain the differences in the evolution of QoI resistance in fungal and oomycetepathogens. Interestingly the characteristic ... might explain differences in the emergence of such resistance. One factor may be subtlevariations in the structure and function of the Qobindingdomain of the pathogens. In this work, the resistance ... (using2.5 nMbc1complex), as in Table 2, was measured in presence of increasing concentration of inhibitors. The concentration of stigmatellin required for 50% decrease of activity (I50) was...
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Báo cáo khoa học:

Báo cáo khoa học: "On the Computational Complexity of Dominance Links in Grammatical Formalisms" doc

Báo cáo khoa học

... encod-ing of an instance of the membership problem forATMs working in polynomial space into an in- stance of the coverability problem for 1-boundedMLIGs. The upper bound is a direct application of ... amultiset of productions in N × V∗and D is a re-lation from nonterminals in the right parts of pro-ductions in P to nonterminals in their left parts,and S in N is the start symbol.A terminal ... Di) in W , at least one of the pi,jshould contain at least one terminal in its rightpart—we have then L(UVG-dl) ⊆ L(MLIG).More on Dominance Links Dominance linksare quite common in...
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