the free body diagram is drawn in figure

... associated with the targeting of LRH-1 into nuclear bodies that is inhibited by cAMP signaling Because the ovary expresses LRH-1, we further examined the effect of sumoylation site mutation on the nuclear ... LRH-1 activity In response to pituitary gonadotropins, the cAMP signaling pathway is the most important pathway in the stimulation of gonadal steroidogenesis [40] In addition, LRH-1 is a potent ... modification of the homeodomain-interacting protein kinase (HIPK2) by the ubiquitin-like protein SUMO-1 Proc Natl Acad Sci USA 96, 12350–12355 40 Conti M (2002) Specificity of the cyclic adenosine 3¢,5¢monophosphate...

Ngày tải lên: 23/03/2014, 06:20

... emphasis on four skills including listening, speaking, reading and writing and other subjects related to English theoretical linguistics The total time allocation and the training curriculum for these ... main stages: setting up (organizing the pairs and group/ giving instructions), monitoring (listening to the pairs/ groups during the activity and guiding / giving support/ making notes) and winding ... Brainstorming 13 Brainstorming is often put to excellent use in preparing students to discuss a complex issue It is a technique whose purpose is to initiate some sort of thinking process Brainstorming...

Ngày tải lên: 07/11/2012, 14:50

... meaning of words denoting parts of the human body in English 1) Abdomen 1 .The part of the body, below the chest, containing the stomach, bowels The back part of an insect 2) Arm Either of the ... before leaving the body: intestine Bowels [pl] the deepest inner part of something 16) Brain a, The organ of the body inside the head that controls thought, memory and feeling b, Brains : the substance ... Ankle 1 .The joint connecting the foot with the leg The thinner part of the leg between this joint and the calf 4) Arse The part of the body one sits on; the anus A person 5) Artery Any of the tubes...

Ngày tải lên: 18/12/2013, 21:45

... Rights.” They agreed to recognize the importance of the dissemination of information from the other participating States”, “make it their aim to facilitate the freer and wider dissemination of information ... expression, freedom of the media and the free flow of information on the Internet The study assesses how these provisions are applied by the participating States Furthermore, the study assesses the compliance ... system for ISPlevel blocking, other ISP-level blocking systems are used in other participating States where voluntary blocking measures exist In almost all instances, blocking lists and blocking criteria...

Ngày tải lên: 18/02/2014, 00:20

... though it did contain one ADPbinding motif This suggests the ADP-binding motif in the a1 subunit mediates the observed ATP binding, and FMN is likely situated at the interface between the a1 and b1 ... analysis This means that ATG, which was situated bp downstream from the 5¢-terminus of the predicted ORF, is the proper initial codon for the a1 gene The N-terminal amino-acid sequence of the b1 ... that one ADP-binding motif mediates FAD binding and the other is responsible for the dye-NADHDH 4049 FAD, FMN and ATP-containing amino-acid dehydrogenase Fig HPLC analyses of the prosthetic groups...

Ngày tải lên: 20/02/2014, 01:20

... of the current interest in database interfaces and in which considerable research is needed Large, shiny nuggets of theory are waiting to be discovered by enterprising computational linguists! ... generalize to the other The fault lies in the inadequate theories, not in the problem environment, and radically changing the problem environment will not guarantee the development of better theories ... query, but this need not be the case The point of the spectrum is that there is a continuum from "database" to "knowledge base", and that the supposed limitations of one arise from the application...

Ngày tải lên: 21/02/2014, 20:20

... linked to, but distinct from, apoptosis [9,10] Beclin 1, a class III phosphatidylinositol 3-kinaseinteracting protein [11], plays a role in promoting autophagy [12] Beclin contains a Bcl-2-binding ... Cells were incubated for 20 in lm Fluo-2 ⁄ AM at 37 °C in MKH buffer Then the dye-containing solution was replaced with dye -free MKH buffer containing 0.1 mm norepinephrine and cells were incubated ... punctae This result was surprising, as the upregulation of autophagy by starvation has been reported in vivo [19], in isolated primary cells [33], and in other cell lines [52] [14,20] This discrepancy...

Ngày tải lên: 07/03/2014, 09:20

... his3:hisG/his3::hisG trp1::hisG/trp1::hisG S1278b; MATa ura3–52 his3:hisG leu2::hisG ras2::kanMX S1278b; MATa/a ras2::kanMX/ras2::kanMX ura3–52/ura3–52 his3:hisG/his3:hisG leu2::hisG leu)2::hisG ... Moesch This study This study This study This study This study This study [30] [31] B Klebl This study This study This study This study This study This study This study This study This study E ... sut2::S.pombe his5+/sut2::S.pombe his5+ ura3–52/ura3–52 his3:hisG/his3:hisG leu2::hisG/LEU2 TRP1/trp1::hisG S1278b; MATa ura3–52 his3:hisG leu2::hisG FLO11::lacZ S1278b; MATa ura3–52 his3:hisG leu2::hisG...

Ngày tải lên: 07/03/2014, 15:20

... change in the spectra was observed, indicating that the temperature-induced change in the fold of the structure is indistinguishable between the three proteins at this protein concentration Furthermore, ... 7.2), showing that the binding of the prosthetic group is considerably impaired Y42H MCAD shows a slight increase in the peak-to-peak ratio (ratio Y42H ¼ 7.5), indicating that FAD binding is also ... the MCAD protein, and at high concentrations the differences between the thermal stabilities of the three proteins becomes almost indistinguishable We could show that the decisive factor is the...

Ngày tải lên: 07/03/2014, 16:20

... of this domain is critical for high affinity agonist binding but not antagonist binding [14] The corresponding residue in the OTR is also an arginyl (Arg34) and furthermore this arginyl is required ... arginyl at this locus is a constraining residue which contributes to maintaining the conformational switch of the V1aR in the off-state The unique ability of arginyl to fulfil this constraining ... the V1aR is required for high affinity agonist binding and signalling It is one of the constraining residues which maintain the V1aR in the inactive conformation and as such is part of the receptor...

Ngày tải lên: 07/03/2014, 21:20

... possibly involved in the anchoring of the protein to the membranes This part of the protein is absent in the prokaryotic MgPIXMT From databank surveys, we detected highly similar proteins in other ... determined by the TMPRED program They are indicated in white letters on black background The amino terminus end of the recombinant truncated proteins (D80-protein and D161-protein) is indicated ... 0.1 M NaOH, indicating that the protein is not a transmembrane protein It is therefore possible that the protein is associated with one lea¯et of the membrane via lipid interaction As the plant...

Ngày tải lên: 08/03/2014, 16:20

... to declines in income by reducing both spending and saving, thereby generating changes in spending that are smaller than the changes in income And the effects on income of some of the tax increases—for ... of the reduction in the employee’s portion of the payroll tax Other expiring provisionsa Taxes included in the Affordable Care Act Subtotal Changes in Specified Spending Policies Effects of the ... reduce national saving, thereby curtailing investment in productive capital and diminishing future output and income Interest payments on the debt would consume a growing share of the federal budget,...

Ngày tải lên: 15/03/2014, 20:20

... replicating the previous findings In contrast, attributing the affecfive response to the music did eliminate the effect of processing facilitation on liking That is, participants who were informed ... in higher perceptual fiuency, and training in arts gives meaning to complex structures in paintings, poems, or music, which results in an additional increase in processing ease Accordingly, the ... perceiver Is beauty therefore in the eye of the beholder? In a sense it is, if folk wisdom thinks of the eye as the perceptual processes of the beholder However, beauty "in the eye of the beholder"...

Ngày tải lên: 16/03/2014, 18:20

... ADP suggests that the mitochondrial injury is caused by opening of the mPTP There is evidence that ADP inhibits opening of the mPTP by occupying binding sites located in the inner and outer mitochondrial ... relevance in brain, because in this tissue glucose is metabolized providing the NADH-yielding substrate pyruvate Under these conditions, some succinate is formed by the citric acid cycle, oxidizing ... micromolar Ca2+ generate H2O2 during reoxygenation that is released into the extramitochondrial space This is in line with in vivo studies of ischemia ⁄ reperfusion showing increased ROS production by...

Ngày tải lên: 16/03/2014, 22:20

... some kinds of chromosome 16 serine proteases, including testisin and prostasin We investigated the expression of prosemin in ovarian cancers using immunohistochemistry Western blot analysis showed ... that prosemin is secreted into the pancreatic fluid is required In other tissues, prosemin may not be involved in the reconstitution of the extracellular matrix, because recombinant prosemin does ... of serine proteases Neurosin ⁄ KLK6, expressed predominantly in the brain, is up-regulated in ovarian carcinomas [10,15] Neuropsin ⁄ KLK8 mRNA is not detected in the normal ovary, but is overexpressed...

Ngày tải lên: 16/03/2014, 23:20

... another band of 82 kDa when the MREa-protein band from the EMSA was excised from the native gel and resolved by SDS/PAGE (unpublished data) We purified the MREa-binding proteins using the avidin–biotin ... N-terminal sequencing of the 70-kDa protein was inhibited by modification, consistent with previous reports showing that the amino terminus of the human Ku-70 protein is blocked and therefore inaccessible ... will also be of interest to examine whether additional proteins bind to the other three MREs in the WD promoter, and if so, to determine the precise mechanisms by which such proteins modulate WD...

Ngày tải lên: 17/03/2014, 23:20

... thêm chi tiết từ đó) Neither of the children is interested in learning 2 Các bạn di chuột vào cụm từ để biết chức cụm câu: Neither of the children is interested in learning 3 Tại câu lại dịch ... *Neither of the children is interested in learning • Hình thức cấu trúc ngữ pháp: Neither of + the/ these/ those…/ my/ your/ his … + N (số nhiều)” – không (trong ... đứa bọn trẻ - is interested in learning” – thích học Cấu trúc từ “to be interested in + Ving” = “to be fond of + V-ing” = “to be keen on + Ving” – thích, hứng thú làm việc Ở “learning” danh động...

Ngày tải lên: 20/03/2014, 00:20