... wild-type R15K R16K R15K ⁄ R16K Y20K C152S 4 018 13 97 67 29 929 12
Ngày tải lên: 07/03/2014, 11:20
... 219 Q 41L 67N 69E 75I 10 3N 10 8I 11 8I 17 8M 210 W 215 Y 41L 67N 74V 10 1Q 18 4V 215 Y 41L 44D 67N 10 1E 10 3N 11 8I 18 4V 210 W 215 Y 219 E n.d 41L 67ss 69S 10 1Q 18 1C 19 0S 215 Y 65R 70R 10 3N 10 8I 11 5F 15 1M 17 9E ... mutations 41L 44D 67N 98G 10 3N 11 8I 210 F 215 Y 219 R 41L 67ss 69S 18 8L 215 Y 41L 11 8I 18 4V 215 Y 41L 44A 67N 75I 10 3N 10 8I 11 8I 210 W 215 Y 41L 67N 69D 70R 74V 10 3N 18 1C 210 W 215 F 219 Q 67N 70R 10 3NS 19 0A 18 4V ... 17 9E 18 4V 219 E 67N 18 4V 210 W 215 Y 219 Q 41L 44D 67N 75L 11 8I 18 1C 18 4V 19 0A 210 S 215 Y 41L 44D 67N 70R 19 0A 227L 18 4V 210 W 215 F 219 R 41L 67N 74V 98G 11 8I 18 4V 210 W 215 Y 227L 41L 44D 10 3N 11 8I 18 4V...
Ngày tải lên: 10/08/2014, 05:22
Báo cáo y học: " The Vpr protein from HIV-1: distinct roles along the viral life cycle" potx
... N, Kim JE, et al.: Vpr R77Q is associated with http://www.retrovirology.com/content/2 /1/ 11 153 15 4 15 5 15 6 15 7 15 8 15 9 16 0 16 1 16 2 16 3 16 4 16 5 16 6 16 7 16 8 16 9 17 0 17 1 17 2 long-term nonprogressive ... BP: NMR structure of the (52–96) C-terminal domain of the HIV- Page of 14 (page number not for citation purposes) Retrovirology 2005, 2 :11 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 regulatory ... analysis of cell cycle arrest, nuclear localization and Page 11 of 14 (page number not for citation purposes) Retrovirology 2005, 2 :11 92 93 94 95 96 97 98 99 10 0 10 1 10 2 10 3 10 4 10 5 10 6 10 7 10 8 10 9...
Ngày tải lên: 13/08/2014, 13:20
A STUDY ON HOW SCRIPTWRITERS FLOUT CERTAIN MAXIMS OF GRICE’S COOPERATIVE PRINCIPLE TO CREATE VERBAL IRONY THROUGH THE SITCOM FRIENDS FROM EPISODE 1 TO EPISODE 10
... 1. 2 .1 Conversational maxims 1. 2 .1. 1 The maxim of quality 1. 2 .1. 2 The maxim of quantity 1. 2 .1. 3 The maxim of relation 10 1. 2 .1. 4 The maxim ... 10 1. 2.2 Observing the maxims 11 1. 2.3 Non-observances of the maxims 11 1. 2.3 .1 Flouting a maxim 12 1. 2.3.2 Violating a maxim 12 1. 2.3.3 ... not be discussed The reason is that thorough studies on these subjects will be too broad for this research 11 1. 6 Design of the study This thesis is divided into three main parts: Part 1: Introduction...
Ngày tải lên: 02/03/2015, 14:22
A STUDY ON HOW SCRIPTWRITERS FLOUT CERTAIN MAXIMS OF GRICE’S COOPERATIVE PRINCIPLE TO CREATE VERBAL IRONY THROUGH THE SITCOM FRIENDS FROM EPISODE 1 TO EPISODE 10
... 1. 2 .1. 3 The maxim of relation 10 1. 2 .1. 4 The maxim of manner 10 1. 2.2 Observing the maxims 11 1. 2.3 Non-observances of the maxims 11 1. 2.3 .1 Flouting ... 1. 1.3 Types of implicature 1. 2 Grice’s cooperative principle 1. 2 .1 Conversational maxims 1. 2 .1. 1 The maxim of quality 1. 2 .1. 2 The maxim ... 1. 6 Design of the study PART 2: THE DEVELOPMENT CHAPTER 1: THEORETICAL BACKGROUND 1. 1 Implicature 1. 1 .1 Definition of implicature 1. 1.2...
Ngày tải lên: 02/03/2015, 14:22
A study on how scriptwriters flout certain maxims of Grice's cooperative principle to create verbal irony through the sitcom Friends from episode 1 to 10
... not be discussed The reason is that thorough studies on these subjects will be too broad for this research 1. 6 Design of the study This thesis is divided into three main parts: Part 1: Introduction ... irony Furthermore, the data are only collected from scripts of the American sitcom “Friends” in the first season (from episode to episode 10 ) in regard with the limit of time Also, this paper ... review This chapter is supposed to provide the readers with the frame of the theory of the study and some basic concepts Chapter II: The study This chapter includes the methods employed by the study,...
Ngày tải lên: 10/08/2015, 19:47
the american practical navigator table 1 logarithms of numbers
... 14 14 14 14 14 13 14 13 14 14 13 13 13 13 13 13 13 13 13 13 13 13 12 13 13 13 13 13 13 13 15 15 14 14 14 14 14 14 14 14 14 13 14 14 14 14 13 13 14 14 14 14 13 13 13 13 14 13 13 13 13 12 13 13 12 ... 13 14 14 14 13 13 13 14 13 13 13 14 13 13 14 13 13 13 13 13 13 13 12 12 13 12 12 12 14 15 15 14 15 14 14 14 14 14 14 13 14 13 14 14 14 13 14 14 13 13 13 13 13 13 13 13 13 13 12 12 13 13 13 13 13 ... 14 14 13 13 13 13 13 12 13 13 13 13 13 13 12 12 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 13 14 14 14 13 13 13 13 13 13 13 12 13 13 13 13 13 12 13 13 13 15 14 14 14 14 14 14 14 14 14 13 ...
Ngày tải lên: 09/05/2016, 08:52
the american practical navigator table 25 change of altitude in given time from meridian ~1
... ′ ′ ′ ″ ″ 1 7 10 12 14 15 17 18 20 21 23 24 26 5 1 3 10 11 13 15 16 18 20 21 23 25 26 28 1 8 10 12 14 16 17 19 21 23 24 26 28 30 1 7 11 13 15 17 19 20 22 24 26 28 30 1 8 10 12 14 16 18 20 22 24 ... 2 1 10 12 15 17 19 21 23 25 27 30 0 1 2 11 13 15 18 20 22 25 27 29 5 1 2 4 12 14 16 19 21 24 26 28 8 1 2 5 10 12 15 17 20 22 25 27 1 2 10 13 16 18 21 24 26 29 1 2 8 11 14 16 19 22 25 28 2 9 11 ... 9 9 9 10 10 10 10 9 9 10 10 10 11 11 11 11 12 18 19 19 20 20 21 22 22 23 23 24 28 28 29 30 ′ ′ ′ ″ 2 7 10 11 12 24 7 10 11 12 25 9 10 11 13 26 1 Caution —If this table is entered with the meridian...
Ngày tải lên: 09/05/2016, 09:02
Tài liệu Báo cáo khoa học: The Arabidopsis protein kinase Pto-interacting 1-4 is a common target of the oxidative signal-inducible 1 and mitogen-activated protein kinases docx
... Grierson FEBS Journal 278 (2 011 ) 11 26 11 36 ª 2 011 The Authors Journal compilation ª 2 011 FEBS C Forzani et al 10 11 12 13 14 15 16 17 18 CS, Hirt H et al (2004) OXI1 kinase is necessary for oxidative ... further analysed (Fig 1B) Three of the prey cDNAs encoded two other FEBS Journal 278 (2 011 ) 11 26 11 36 ª 2 011 The Authors Journal compilation ª 2 011 FEBS 11 27 pBD-OXI1 pBD-OXI1 pBD pBD-OXI1 pBD-PTI1-4 ... pGreenII 0029 [40] The MYC tag was cloned SmaI-XbaI into this FEBS Journal 278 (2 011 ) 11 26 11 36 ª 2 011 The Authors Journal compilation ª 2 011 FEBS 11 33 PTI1-4, a common target of OXI1 and MAPKs C...
Ngày tải lên: 14/02/2014, 19:20
Tài liệu Báo cáo khoa học: The PA-TM-RING protein RING finger protein 13 is an endosomal integral membrane E3 ubiquitin ligase whose RING finger domain is released to the cytoplasm by proteolysis ppt
... 9.4 10 .3 8 .1 9 .1 10.9 9 .1 12.6 11 .2 9.4 11 .8 11 .3 2.9 1. 5 6.7 3.6 1. 0 11 .5 1. 0 2.7 5.5 1. 0 1. 5 in both liver and brain, consistent with our findings in adult tissue Fig 10 RNF13 expression is increased ... or 16 .5 days of development (Table 1) Our analysis of embryonic tissue showed similar expression of RNF13 B RNF13 +DMSO C RNF13 +MG132 RNF13 ICD Fig Expressed RNF13 ICD is not localized in the ... proteolysis from the TM anchor localized approximately in the middle of the protein A Anti-FLAG B Anti-HA 54 - 38 Ctl Virus ICD RNF13 +DMSO+MG132 RNF13 +MG132 Fig RNF13 undergoes proteolysis on...
Ngày tải lên: 18/02/2014, 08:20
Tài liệu An Aviator''''s Field Book Being the field reports of Oswald Bölcke, from August 1, 1914 to October 28, 1916 doc
... Field Near the North Sea 14 5 Ready for the Start 16 0 Bölcke and His Brother Max in France (August, 19 16) 16 1 One of His Last Victims 18 2 Starting on His Last Ride, October 28, 19 16 P M 18 3 FOREWORD ... Bölcke was born on the 19 th of May, 18 91, in Giebichenstein, a suburb of Halle on the Saale Here his father was professor in the high school His sister, Luise, and his two brothers, Wilhelm and ... his machine; then he "fluttered" to earth; i.e., fell This was the fourth one OCTOBER 17 , 19 15 Yesterday, the 16 th, I shot down a French Voisin biplane near P R., NOVEMBER 2, 19 15 On the 30th of...
Ngày tải lên: 18/02/2014, 09:20
Tài liệu Báo cáo khoa học: Helix mobility and recognition function of the rat thyroid transcription factor 1 homeodomain – hints from 15N-NMR relaxation studies pdf
... (0.04) (0 .19 ) (0.09) 19 83 2493 14 86 18 85 10 30 16 30 13 45 10 38 19 60 805 514 (406) (13 74) (780) ( 710 ) ( 613 ) (809) (740) (542) (10 47) (752) (277) 19 64 15 61 1008 15 96 905 12 97 11 42 468 14 03 276 206 ... ¨ 13 14 15 16 17 18 19 20 21 22 23 24 25 26 nuclear 1H 13 C correlation spectroscopy J Am Chem Soc 11 0, 7557–7558 Kay LE, Torchia DA & Bax A (19 89) Backbone dynamics of proteins as studied by 15 N ... Leu26 Table lists the mean J(x) values together with the corresponding standard deviations for the different secondary structure elements of the TTF -1 HD It is readily seen that the 15 N–1H vectors...
Ngày tải lên: 18/02/2014, 16:20
Tài liệu Báo cáo khoa học: An alternative transcript from the death-associated protein kinase 1 locus encoding a small protein selectively mediates membrane blebbing pdf
... 13 14 of the DAPK -1 gene Its coding region starts from the 10 th base pair on exon 15 of the DAPK -1 gene, and shares the same splicing as full-length DAPK -1 through the rest of exons 15 , 16 , 17 , ... PLACE7 011 559, from the NEDO human cDNA sequencing project The mRNA of this expression clone starts on intron 13 14 of the DAPK -1 gene and stops on intron 20– 21 (Fig 1A) The start codon, ATG, of this expression ... 16 , 17 , 18 , 19 and 20 s-DAPK -1 s coding region stops at the 12 6th base pair of intron 20– 21 of the DAPK -1 gene, and the 3¢-UTR extends through the middle of intron 20– 21 (B) Comparison of the protein...
Ngày tải lên: 18/02/2014, 17:20
Tài liệu Báo cáo khoa học: Different modes of dipeptidyl peptidase IV (CD26) inhibition by oligopeptides derived from the N-terminus of HIV-1 Tat indicate at least two inhibitor binding sites doc
... (M) 2.67 2.30 1. 50 4.87 1. 75 4.27 2 .12 1. 70 1. 24 2.69 2.00 4.36 5.02 1. 59 2.45 · · · · · · · · · · · · · · · a )4 10 10 )4 10 )4 10 )4 10 )3 10 )5 10 )6 10 )6 10 )5 10 )4 10 )4 10 )5 10 )6 10 )5 10 )5 c d Type ... 1. 13 · 10 )5 M, S Lorey, unpublished results) The substitutions of Met1 [Trp1-Tat (1 9)] or Pro3 of Tat (1 9) [Gly3-Tat (1 9), Ile3-Tat (1 9)] did not change the inhibition type The Ki values of the ... of the Dixon plot and/or Lineweaver–Burk plot Compound Tat (1 9) Tat (1 9)a Trp1-Tat (1 9) Gly3-Tat (1 9) Ile3-Tat (1 9) Lys2-Tat (1 9) Trp2-Tat (1 9) Trp2-Tat (1 9)* Met-Trp1-G-CSF (1 8) Met-IL-2 (1 12 )...
Ngày tải lên: 20/02/2014, 11:20
Tài liệu Báo cáo khoa học: Phenol hydroxylase from Acinetobacter radioresistens S13 Isolation and characterization of the regulatory component docx
... radioresistens S13 is identical (from residue number 3) to the sequence of the corresponding component of PH from A calcoaceticus NCIB 8250 (11 /11 identity) [3] and very similar to that of the corresponding ... radioresistens S13 strain used in this work was isolated as previously described [16 ,17 ] This bacterium bears several natural plasmids and is able to grow on either phenol or benzoate as the only ... Tris/sulfate buffer, pH 8.5, using NADH as the electron donor Cytochrome c NBT Km (lM) PHR PHR + PHI kcat (s )1) kcat/Km (s )1 lM )1) Km (lM) kcat (s )1) kcat/Km (s )1 lM )1) 1. 3 ± 0.3 1. 5 ± 0.2 61...
Ngày tải lên: 21/02/2014, 00:20
Tài liệu The Days of Bruce Vol 1 A Story from Scottish History ppt
... the commands of his master "They said not the direction of their course, my liege; 'tis thought to reconnoitre either the movements of the English, or to ascertain the cause of the delay of the ... from foreign foe, and give the rightful heir his due?" "I know not, Isabella There remain but few with the pure Scottish blood within their veins, and it is but to them our land is so dear: they ... in the superstition of the time, argue well for the fortunes of one brother from the marvellous effect observable in the countenance and mood of the other The hopefulness of youth, its rosy visions,...
Ngày tải lên: 22/02/2014, 03:20
Báo cáo khoa học: SAF-3, a novel splice variant of the SAF-1/MAZ/Pur-1 family, is expressed during inflammation pptx
... stimuli such as cytokines [12 ], phorbol 12 -myristate 13 -acetate [13 ], lipopolysaccharide [14 ] and oxidized low-density lipoproteins [15 ] have been shown to activate SAF -1 protein and increase its ... FJ532357), with SAF -1/ MAZ/Pur -1 being the originally identified isoform [1 3] Comparison of amino acid sequences indicated that the N-terminal region of SAF-3 is different from that of SAF -1, after which ... of the SAF-3 splice variant A kgt -11 cDNA library was prepared using mRNAs isolated from IL-1b-induced human HTB-94 cells The library was screened using an SAF -1 cDNA probe The DNA inserts from...
Ngày tải lên: 07/03/2014, 02:20
Báo cáo khoa học: NMR investigations of subunit c of the ATP synthase from Propionigenium modestum in chloroform/methanol/water (4 : 4 : 1) pot
... [28], 3D 13 C-resolved HCCH-TOCSY (sm ¼ 14 ms) [29], 3D 15 N-resolved [1H,1H]-NOESY (sm ¼ 60 ms) [30], 3D 13 Cresolved [1H,1H]-NOESY (sm ¼ 60 ms) [ 31] , and 3D 13 Cresolved [1H,1H]-NOESY (sm ¼ 15 0 ms) ... overlap The 13 C chemical shifts were obtained by 3D 13 C-resolved HCCH-COSY, 3D 13 C-resolved HCCH-TOCSY and 3D 13 C-resolved [1H,1H]-NOESY experiments However, chemical shift dispersion of the methyl ... J Magn Reson 10 1, 2 01 205 Marion, D., Kay, L.E., Sparks, S.W., Torchia, D.A & Bax, A (19 89) Three-dimensional heteronuclear NMR of 15 N-labeled proteins J Am Chem Soc 11 1, 15 15 15 17 Bax, A., Clore,...
Ngày tải lên: 08/03/2014, 10:20
Báo cáo khoa học: An intermediate step in the evolution of ATPases ) the F1F0-ATPase from Acetobacterium woodii contains F-type and V-type rotor subunits and is capable of ATP synthesis Michael Fritz and Volker Muller ¨ docx
... c1 does not abolish ATP synthesis by the Na+ F1F0-ATP synthase from A woodii Discussion The Na+ F1F0-ATP synthase from the anaerobic, acetogenic bacterium A woodii purified here contained all the ... synthesis by F1F0 ATP synthases J Exp Biol 203, 51 59 Kaim G & Dimroth P (19 99) ATP synthesis by F-type ATP synthase is obligatorily dependent on the transmembrane voltage EMBO J 18 , 411 8– 412 7 ... Characterization of the Na+ F1F0-ATP synthase from A woodii The specific ATPase activity of the complete enzyme was in the range 5–9.9 UÆmg )1 protein, depending on the batch This is in the same range as the one...
Ngày tải lên: 23/03/2014, 09:20
Báo cáo khóa học: Fidelity of targeting to chloroplasts is not affected by removal of the phosphorylation site from the transit peptide doc
... Wintz, H (20 01) Overlapping destinations for two dual targeted Chloroplast targeting fidelity (Eur J Biochem 2 71) 515 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 glycyl-tRNA synthetases ... bar is 50 lm in the images on the left, and 10 lm in the higher magnification images from regions in (A), (C) and (E), shown on the right acyl-tRNA synthetases, CtRS and HtRS, from A thaliana These ... (P/G)Xn(K/R)Xn(S/ T)Xn(S*/T*) [13 ], where the asterisk indicates the site of phosphorylation and n is a spacer of 0–3 residues (Fig 1A) Figure 1B indicates the phosphorylation motifs in the transit peptides...
Ngày tải lên: 23/03/2014, 12:20