... promoters, mutation of the CHR leads to a more pronounced deregulation than the alteration of the CDE [40]. Another gene tested for its cell cycle regulation is the cellular inhibitor of apoptosis protein ... If the DREAM complex is the main regulator of CDE ⁄ CHR cell cycle genes, to which promoter sites does it bind during any par- ticular phase of the cell cycle? What is the exact mechanism of ... turns of the DNA double helix yields binding of the two or three NF-Y complexes on the same side of the DNA. Conservation of spacing is required for optimal pro- moter activity because changing the...
Ngày tải lên: 16/02/2014, 09:20
... into furthering the interests of another country at the expense of Australia’s interests. 9 e end of the Cold War, the rise of al Qaeda, preparations for the 2000 Olympic Games in Sydney, the ... Considering the Creation of a Domestic Intelligence Agency in the United States the Audit and Evaluation Committee, which sets the parameters t for determining the utility and accuracy of ASIO threat ... of unconventional agents for the purpose of mass destruction (ASIO, 2006, pp. 25–26). In pursuing these various functional tasks, ASIO employs a staff of 1,400 (as of October 2007) and, at the...
Ngày tải lên: 15/03/2014, 21:20
Báo cáo khoa học: "The Creation of a Corpus of English Metalanguage" pptx
... language technologies, to the detriment of the performance of systems that could exploit it. This paper describes the creation of the first tagged and delineated corpus of English metalanguage, ... known as duck , and the brothers began making work pants and shirts out of the strong material. NN Digeri is the name of a Thracian tribe mentioned by Pliny the Elder, in The Natural History. ... language 4 . The researcher also identified four categories of mentioned language based on the nature of the substitution phrase X’ specified by the rubric. These categories will be discussed in the...
Ngày tải lên: 16/03/2014, 19:20
fixed broadband wireless system design the creation of global mobile communications
Ngày tải lên: 03/06/2014, 00:52
The chart shows the number of mobile phones and landlines per 100 people in selected countries ppsx
Ngày tải lên: 07/07/2014, 12:20
Báo cáo sinh học: "The nature of cell-cycle checkpoints: facts and fallacies" docx
Ngày tải lên: 06/08/2014, 19:21
báo cáo khoa học: "PVP-coated silver nanoparticles block the transmission of cell-free and cell-associated HIV-1 in human cervical culture" ppsx
Ngày tải lên: 11/08/2014, 00:22
A CFD analysis on the effect of ambient conditions on the hygro-thermal stresses distribution in a planar ambient airbreathing PEM fuel cell
Ngày tải lên: 05/09/2013, 14:58
The Use of Plant Cell Biotechnology for the Production of Phytochemicals
... elucidation of specific biosynthetic enzymes, and the identification of end-products. The complete genetic makeup of an organism has been generated in the plant sciences as well. Because of the success of ... made in plant cell cultures of C. roseusby Dos Santos et al. (1994) concerning equality of the rate of catabolism with the rate of de novo compound biosynthesis. The phenomenon of catabolism ... of the influence of environmental or genetic factors on phenotype sustainability, and (3) alteration of the phenotype of the selected host by genetic manipulation. Chapter 2 The Use of Plant Cell...
Ngày tải lên: 25/10/2013, 05:20
Tài liệu Control the Creation and Behavior of Classes Now that you have code that can prepare all of the pdf
... modifying the values in the data row, and thus the dataset. In short, the data row holds the original state of the Customers row, whereas the class-level variables hold the current state. At the ... from the database. If not, an exception is thrown that notifies the developer of the problem. Of course, a developer could ignore your exception and attempt to access the properties of the ... constructor, other developers must provide a CustomerID when they attempt to create an instance of the CCustomer class. If a corresponding row is in the Customers table, the properties of the class...
Ngày tải lên: 24/12/2013, 06:17
Tài liệu Báo cáo khoa học: MicroRNA-23a promotes the growth of gastric adenocarcinoma cell line MGC803 and downregulates interleukin-6 receptor pdf
... confirmed the active role of miR-23a in the growth promotion of malignant cells. The fundamental function of miRNAs is to regulate their targets by direct cleavage of mRNA or by inhibi- tion of protein ... further studies. Collectively, our studies demonstrate that miR-23a potently promotes the growth of the gastric adeno- carcinoma cell line MGC803, providing the first proof- of- concept that there ... with the 3¢ UTR of target genes. Further- more, the 2–8 nucleotides of miRNA, known as the ‘seed region’, have been suggested to be the most important region for target recognition [16]. Therefore, we...
Ngày tải lên: 18/02/2014, 04:20
Tài liệu Báo cáo khoa học: Osmosensing and signaling in the regulation of mammalian cell function docx
... that cell volume fluctuations release signals of (patho)physiological relevance. The understanding of how cell swelling integrates into the cell cycle machinery and how cell shrinkage sensitizes cells ... H4IIE rat hepa- toma cells to pro-apoptotic signaling by the protea- some inhibitor MG-132 [40]. These and other studies on hyperosmotically shrun- ken cells support the view that the apoptotic volume decrease, ... apoptotic stimuli requires further scientific effort. Cell hydration may markedly affect the action of drugs. For example cell hydration changes may switch the outcome of proteasome inhibitors from...
Ngày tải lên: 18/02/2014, 16:20
Tài liệu Báo cáo khoa học: Hypoxia reduces the expression of heme oxygenase-2 in various types of human cell lines A possible strategy for the maintenance of intracellular heme level pdf
... degrada- tion in the population of hemoglobin-positive cells. To the best of our knowledge, there has been no report on the promoter function of the human HO-2 Fig. 7. Characterization of the human ... indu- ces the expression of the a-globin gene in K562 human erythroleukemia cells [33] and the number of hemoglo- bin-producing cells in YN-1 cells [27,34]. Conversely, the deficiency of heme in ... analyzed the promoter function of the 1.5 kb 5¢-flanking region of the HO-2 gene in the present study. YN-1 cells were transfected with each construct of the HO-1 and HO-2 gene promoters (Fig. 7B). The...
Ngày tải lên: 19/02/2014, 06:20
Tài liệu Báo cáo khoa học: Altered expression of CD1d molecules and lipid accumulation in the human hepatoma cell line HepG2 after iron loading pptx
... of CD1d molecules at the cell surface of iron-loaded HepG2 cells in a non-native form may have implications at two different levels; at the level of the hepatic cell itself and at the level of ... cytometry revealed that the inhibition of cell growth was due to a decrease in the percentage of cells in the S and G2 ⁄ M phases of the cell cycle (Fig. 3B). In a total of seven separate determinations, ... of the relationship with neighboring cells. At the level of the hepatocyte, CD1d redistribution may influence quanti- tatively and qualitatively the intracellular lipid pool by either intracellular...
Ngày tải lên: 19/02/2014, 16:20
Tài liệu THE MANAGEMENT OF SICKLE CELL DISEASE ppt
... information about the specific type of SCD that affects their child (4-6). The ini- tial counseling session sets the tone for how the parents regard their child’s condition and the new health care ... precipitating factors, so that they do not blame themselves or their children. Likewise, health care providers should not assume that the pain is due to the fault of the parent. Children with pain ... localize the exact site of pain, to ensure that a limp is due to pain and not weakness, and to assess the degree of pain for appropriate treatment. The object of pain management is relief, even in the...
Ngày tải lên: 21/02/2014, 12:20
Hydroxyurea for the Treatment of Sickle Cell Disease docx
... reviewer reconciled the results of the first two reviewers; for the other study designs, the results of the two reviewers were averaged. The overall score was the percentage of the maximum possible ... Most of the therapies offered to patients with sickle cell disease are supportive and do little to change the underlying pathophysiology of the disease. These supportive measures include the ... hydroxyurea treatment of hematologic diseases, the toxicity of hydroxyurea in the treatment of any disease, and the barriers to the treatment of sickle cell disease with hydroxyurea or other agents....
Ngày tải lên: 05/03/2014, 10:20
Báo cáo khoa học: Characterization of a cathepsin L-associated protein in Artemia and its relationship to the FAS-I family of cell adhesion proteins pot
... major bands in e and f, while the numbers at the left are the pI values of standard proteins. The arrow at the right represents the pI value of 6.84 calculated for the unmodified CLAP p rotein based ... of the fasciclin I domains in CLAP with selected proteins in the protein database. The Conserved Domain Database of NCBI was screened with the protein coding sequence of clone 1 of CLAP and the ... sequence analysis of CLAP and cDNA clones coding for CLAP s how it to be a cell adhesion protein and member of the fasciclin I family of proteins. These results support the hypothesis that CL in...
Ngày tải lên: 07/03/2014, 16:20