the contribution of forensic molecular pathology in medical science

... conformation In this way, Curtis-Fiske et al were able to identify native a-helices of the N-terminal 185 residues of the functional domain of the HA2 subunit of the in uenza virus hemagglutinin protein ... multidomain proteins, fusion proteins In the following we summarize recent progress in this field, whereas the use of IBs in the study of amyloid aggregation is developed in the accompanying review ... refolding is often a critical step in the production of recombinant proteins Interestingly the approach has been successfully tested with proteins not related in their structure, among them the...

Ngày tải lên: 06/03/2014, 00:20

... membrane [30] The identication of proteins located on the extracellular surface and involved in the decrease in Eh would be of interest for increasing our understanding of the mechanisms involved ... by the production of end-products with reducing metabolisms L lactis is able to maintain a low Eh7 until the end of fermentation and for 24 h [16] The role of the active mechanisms in maintaining ... attractive model for investigating new mechanisms involved in the reducing activity of microorganisms This was the aim of the present study Thiol groups in the reducing activity of L lactis 50 5.0...

Ngày tải lên: 22/03/2014, 21:21

... on the interaction of the intrinsic strength of a boundary with the strengths of other boundaries in the sentence, as well as the distance between these boundaries The most salient of the interactions ... phrases-like Fina[Iv as dominated by the comi~lementizer node in the s)ntax tree and it is difficult to determine whether the) ' integrate the material in the comptemennzer Wltla the material in the core ... rightadjoining: on each, in 48-channel, can power, the echo, that are and in that These groups of adjoined words a p p e a r as terminals in the prosody tree in Figure In subsequent processing the...

Ngày tải lên: 24/03/2014, 02:20

... and facts in legal cases that also offers expert opinions regarding their findings in court of law The science in question here is accounting science, meaning that the examination and interpretation ... Reviewing of the relevant documentation to form an initial assessment of the case in an identified area of loss Examination for discovering, including the formulation of the act regarding the financial ... require the service of forensic accounting in Nigeria An average of about 32% belief the experts are more required in the remaining areas TESTING OF HYPOTHESIS Hypothesis one null states that there...

Ngày tải lên: 29/03/2014, 14:20

... is critical in providing proper docking sites, either directly or indirectly, by modifying the conformation of PSII on the lumenal side, making efficient binding of PsbQ and PsbP of the OEC possible ... Dynamic interaction between the D1 protein, CP43 and OEC33 at the lumenal side of photosystem II in spinach chloroplasts: evidence from lightinduced cross-linking of the proteins in the donor-side ... accumulating all three proteins of the OEC and traces of the D2 and CP43 core proteins as well (Fig 1B) The presence of minor amounts of D2 in both DpsbE and DpsbF supports the suggestion that the...

Ngày tải lên: 30/03/2014, 13:20

... well with the estimated doubling time of EL4 cells in logarithmic growth No major variation in the mRNA half-life of cyclin mRNAs in the cell cycle In order to test whether changes in mRNA steadystate ... the cell cycle [11–15] Certain transacting proteins such as HuR were proposed as regulators of changes in mRNA stability during the cell cycle [15] In this context it is of interest that during ... the changes in mRNA half-life may explain almost fully the accumulation of the short A2 and B1 transcripts as well as partially the 3.0-kb A2 transcript In contrast, the greater increase of the...

Ngày tải lên: 30/03/2014, 20:20

Ngày tải lên: 31/03/2014, 14:20

... challenges in recruitment and employment The interviews provided insights in the perceptions of the organization regarding the role and contribution of their international health volunteers In a third ... doing on -the- job training and bedside teaching; ▪ Strong management (including infrastructure) capacity of certain expatriates; ▪ Improved quality of teaching in educational institutions Most informants ... experienced medical officers from sub-Saharan African countries The participants were drawn from the students of the international master in public health of the Institute of Tropical Medicine, Antwerp,...

Ngày tải lên: 18/06/2014, 17:20

... altitude forests (e.g Zejda 1973) In all of them Cg is one of the dominant species In our study we concentrated on the study of the population of this species as also some other authors did (Alibhai, ... (2004) and some others, large crops of tree seeds in forests positively influence the dynamics of seed eating small mammals in a year after the “seed year” In RB the population of Cg was permanently ... DISCUSSION During the study of small mammal populations in three large forest complexes in southern Moravia Cg was one of the most dominant species The lowland forest was characterized by the highest...

Ngày tải lên: 07/08/2014, 03:22

... stands In the present paper, the population dynamics of As is described in larger forest complexes of southern Moravia depending on the biotope and food supply including the response of the population ... stand and the number of acorns was determined on each of the plots The acorns were then hulled and the net weight of kernels without peel was determined in grams These weights were then averaged ... course of monitored years depending on the crop of small-seed species in 2001 and of acorns in 2003 and 2006 The preference of small seeds of tree species can influence its abundance there (Flowerdew...

Ngày tải lên: 07/08/2014, 03:22

... identication of the species and the estimation of the degradation intensity of crown structure of each inventoried tree are accurate when they are based on the use of three-dimensional information obtained ... absorption in the SWIR is less intense than in the visible range for typical green leaves and therefore the reectance of tree canopies in the SWIR is greater than in the visible range and lower than in ... assessment Finally, the feasibility of depicting forest decline is closely depending on the topography of the study area, on the structure of forest stands, on the date and frequency of data acquisition...

Ngày tải lên: 07/08/2014, 16:20

... decay rate of wood products used in the Finnish buildings, fitting the stocks obtained with a dynamic model to the stocks obtained by direct inventories, by tuning the lifetime parameter of the model ... fraction in paper (0.25) and of the inclusion of inherited emissions before 1961 by assuming an exponential growth of the consumption of wood products in that period The simplification made in this ... that the maximum values of the annual decay rates are the double of the default values (and, consequently, the lifetimes were reduced to half of the default values) The minimum values of the annual...

Ngày tải lên: 08/08/2014, 00:22

... probe inserted in the soil to a depth of 10 cm in the vicinity of the soil respiration chamber Volumetric water content of the soil (&thetas; ) v was measured every 10 cm in depth on the main plot ... trenching The remaining fine root necromass was then compared to initial fine root biomass and necromass in soil cores Coarse roots (2-10 mm in diameter) excavated during the installation of the ... annual fine root production from the number of roots grown into the cores over year [19, 20] Soil Fine root was estimated by coring and dead roots in the trenched plots sorting remaining years...

Ngày tải lên: 08/08/2014, 14:21

... microspheres, thereby minimizing interference with debris (Figure 1a, left panel) The NPA in the clinical sample is then obtained by measuring the mean fluorescence intensity resulting from the loss of ... with the levels of leukocytes, further emphasize the importance of infiltrating leukocytes in controlling the NPA of SF Our results thus illustrate the need to measure the NPA resulting from the ... simply the presence of proteases, in patients during the course of their disease and under the influence of treatment This may represent a sine qua non to achieve clinical success in the development...

Ngày tải lên: 09/08/2014, 08:22

... MRI of the affected region, together with whole skeleton bone scintigraphy and CT of the chest MRI is essential in the determination of the true extent of the tumor It is important to bear in mind ... Reinus WR, Wilson AJ: Quantitative analysis of the plain radiographic appearance of Ewing’s sarcoma of bone Invest Radiol 1997, 32:59-65 10 Reinus WR, Gilula LA: Radiology of Ewing’s sarcoma: Intergroup ... spread of Ewing’s sarcoma, involving small bones to adjacent bones, have not been described in the recent literature It wasn’t possible to determine the exact local extent of the tumor by means of...

Ngày tải lên: 10/08/2014, 23:20

... splicing in concert with protein intrinsic disorder enables increased functional diversity in multicellular organisms Proceedings of the National Academy of Sciences of the United States of America ... are assigned to the individual peptides in the initial in silico peptide populations These pooling probabilities simply reflect the relative abundances of the peptides within the initial populations ... outcome of these in silico experiments involved the pooling probabilities that were assigned to the individual peptides in the initial population We performed the in silico experiments using two...

Ngày tải lên: 11/08/2014, 11:20

... glutathione [18] In addition, the HIV regulatory proteins induce a reduction of expression and activity of MnSOD, the mitochondrial isoform of the enzyme [23], leading to a sustained generation of superoxide ... both the p24 as the precursor p55 formation, revealing the ability of MnTBAP to block the maturation of p24 viral protein Selective inactivation of peroxynitrite in HIV-1 infected macrophges Furthermore, ... in cultures of M/M and compared with the infectivity of not treated HIV-1 infected M/M supernatants taken at the same time-point The infectivity of supernatants of not treated HIV-1 acutely infected...

Ngày tải lên: 13/08/2014, 05:22

... the kinship between breeds, and (2) an increase in the within breed kinships (i.e continued inbreeding within a population) In the latter situation, criterion does not hold, since continued inbreeding ... possible, the average coefficient of kinship in the core set of S should be minimised In the case of the former example the solution would be the removal of population (or equivalently, removal of population ... founder of the pair (i, j)) Essentially the distance between i and j is determined by the increase in kinships (or the amount of inbreeding) since the founder of i and j Given that fij remains unchanged...

Ngày tải lên: 14/08/2014, 13:21

... Finally, the kernel informs the hardware physical map module of the new virtual to physical mapping With the exception of the hardware validation, all of these steps are implemented in a machine-independent ... efficiently support the large body of UNIX software used within the academic community [16] In addition, from the point of view of a system designer, the Accent style of message/memory integration lacked ... once, possibly in different tasks The memory region specified by address in the vm_allocate_with_pager call will be mapped to the specified offset in the memory object The offset into the memory...

Ngày tải lên: 12/09/2012, 15:05

... non-lexicalization of the concepts, the lack of super ordinates of hyponyms etc The main contribution of this paper is to draw out the main ways of dealing with the hurdles by investigating how an experienced ... some minor inappropriateness such as the inconsistency in translating the same words, the misuse of some lexical items and the translation of nominal group 2.2.2 Other types of equivalence In the ... words is that the translations of the same words are not consistent from the beginning The other inappropriateness, to the best of my understanding, is the translation of nominal group There are...

Ngày tải lên: 07/11/2012, 14:31