the capital city of the cakchiquels

... affair is a copy of part of Gascoigne's account, of which the following is a transcript:— [Pg 20] THE OFFICE OF THE POSTE. In the office of William Dodington, Esquire, Auditor of Her Matie. ... forward in the street; on the east side being another building answerable thereto." These premises served as the Post Office for the long period of 118 years. The first half of the present ... parcel of ground situate in the Parish of St Werburgh in the City of Bristol on the South West side of and fronting to Small Street aforesaid specified in the plan drawn in the margin of the first...

Ngày tải lên: 17/02/2014, 02:20

... improve the human capital or skills of a country’s population, or to facilitate the employ- ment of human capital in diverse sectors of the economy. Table 1.1 provides the categories of reforms ... interest in human capital and economic initiatives. 12 Facing Human Capital Challenges of the 21st Century We used the interview notes to provide an overview of the areas of human capital deficits ... arguably the most comprehensive in the region; changes initiated in 2002 address the management and delivery of educational services, the curriculum, and the quality of teachers and other critical...

Ngày tải lên: 18/02/2014, 02:20

Ngày tải lên: 18/02/2014, 11:20

... obtained with the transition at posi- tions 1915 and 1917. These mutations had an effect on the formation of pseudouridine exclusively at the mutant position and did not affect either of the other two ... by Southern analysis. The rluD::cat strain had a full deletion of both rluD and yfiH, together with their annotated pro- moter sequences. The inserted cat cassette had a distance of 90 nt from the ... primer extension. The primer exten- sion stop on the CMCT treated RNA (+ lane) indicated the presence of pseudouridine at the particu- lar position when the stop was not present in the con- trol...

Ngày tải lên: 18/02/2014, 16:20

... for the opposite-base speci city of Fpg and OGG1. Also, although the buffering capacity of KGlu at pH 7.5 is much weaker than that of KP i , the omission of KP i had a rather minor effect on the ... Fig. 2. In the absence of MgCl 2 , the affinity of Fpg for the THF:C ligand was 1.6-fold higher than for the THF:A ligand. The presence of Mg 2+ had little effect on the binding of Fpg to the THF:C ... 0–5 mm MgCl 2 . The C ⁄ A speci- city of the glycosylase reaction in the absence of KP i was usually higher than in the presence of KP i due to less efficient cleavage of 8-oxoG:A; the highest specific- ity...

Ngày tải lên: 18/02/2014, 18:20

... presumably, contain the sites of O-glycosylation, but we have not identified the specific site(s) or the form of the O-glycans. The CD spectrum of Cel74A looks a lot like that of an unordered protein ... 4, and may be the basis for the unique mode of action of this enzyme. More definitive statements await the solution of the Cel74A structure, which is currently underway. Conclusions The xyloglucanase ... incubation with Cel74A, and the proposed cleavage pattern (C) with the theoretical m ⁄ z value (z in superscript) of the most important fragments (the position of the Gal residues is arbitrary)...

Ngày tải lên: 19/02/2014, 05:20

... has Fig. 5. Analysis of the enzymatic activity of His-CoaB R206Q and A276V. The synthesis of 4¢-phosphopantothenoyl-CMP (–cysteine, upper part of the figure) and of 4¢-phosphopantothenoylcysteine (+ ... synthesized in five steps from D -pantothenate. The Dfp flavoprotein catalyzes the synthe- sis of the coenzyme A precursor 4¢-phosphopantetheine from 4¢-phosphopantothenate and cysteine using the ... formation of 4¢-phosphopantothenoyl-CMP (activation of the carboxyl group of 4¢-phosphopantothenate). In a second step, the amide bond of PPC (shaded in grey) is formed by reaction of 4¢-phosphopantothenoyl-CMP...

Ngày tải lên: 19/02/2014, 12:20

... than the true value, underlining the impact of quite a small level of contamination on these results. Reassessment of the effects of the mutations on coenzyme speci city In view of the dramatically ... moiety of the coenzyme resulting from splitting off the nicotinamide ring, suggesting that the covalent bond between the nicotinamide and the ribose of the coenzyme is particularly labile. The signal ... that apparent rates of NADP + utilization mainly reflected the reduction of con- taminating NAD + , creating an entirely false view of the initial coenzyme speci city and also of the effects of mutagenesis....

Ngày tải lên: 06/03/2014, 00:20

... applicability of the nucleotide affinity cleavage technique to study the speci city of the nucleotide binding sites. Since GTP is a C-terminal-specific nucleotide, we further analyzed the properties of Hsp90 ... an intact adenine ring; the stick model is the structure of the kinked ADP in the Hsp90 crystal, the phosphates pointing out of the domain;Rstandsforphosphates(ATP)orothermoietiesasinNAD or adenosine ... of ADP [20]. The reason for this may be that the ATP-bound resin may impose a steric hindrance to the binding of the terminal phosphate, therefore Hsp90 adopts an ÔADP-conformationÕ [20] on the...

Ngày tải lên: 08/03/2014, 02:21

... conformers of the substrate are suitably oriented to point with the proS-hydrogen atom of the Cb group towards the catalytic iron. With an iron– hydroxyl distance of 3.1 A ˚ , the structure of the VioC•hArg•Fe(II)•succinate ... for the asparagine oxygenase AsnO and other mem- bers of the clavaminic acid synthase-like superfamily. Additionally, the sub- strate speci city of VioC was investigated. The side chain of the ... concerning the adenylation domain (A-domain) speci city of VioF revealed b-ureidoalanine activation, leading to the proposition of a new model for the order of the NRPSs during viomycin biosynthe- sis...

Ngày tải lên: 16/03/2014, 02:20

Ngày tải lên: 16/03/2014, 13:20

Ngày tải lên: 22/03/2014, 16:20

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Ngày tải lên: 28/03/2014, 20:20

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Ngày tải lên: 24/05/2014, 08:55

Ngày tải lên: 24/05/2014, 20:29