t 14 18 q32 q21 follicular and diffuse large b cell lymphomas

báo cáo khoa học: "ALK-positive diffuse large B-cell lymphoma: report of four cases and review of the literature" pptx

báo cáo khoa học: "ALK-positive diffuse large B-cell lymphoma: report of four cases and review of the literature" pptx

... identify patients with a better prognosis and < /b> to develop newer therapeutic techniques Consent Written informed consent was obtained directly from patients and < /b> from the parents of patient for publication ... in transplanted cases was between and < /b> 44 months after diagnosis The case treated with allogeneic HSCT died of thrombotic thrombocytopenic purpura (TTP) months after transplantation [30] From the ... [1,5,7,10,11 ,14,< /b> 30] Four patients received autologous HSCT, one patient underwent allogeneic HSCT and < /b> patients were treated with non-specified HSCT All but one of the cases died after transplantation; the...

Ngày tải lên: 10/08/2014, 22:20

10 300 0
báo cáo khoa học: "eneration of diffuse large B cell lymphomaassociated antigen-specific Va6/Vb13+T cells by TCR gene transfer" pdf

báo cáo khoa học: "eneration of diffuse large B cell lymphomaassociated antigen-specific Va6/Vb13+T cells by TCR gene transfer" pdf

... common antiDLBCL cytotoxicity, which was thought to target the TAA of DLBCL This study provides substantial new data for a better understanding of the strategy of adoptive immunotherapy in DLBCL Acknowledgements ... both types of transgene cassettes, indicating that the recombinant plasmids had been constructed successfully and < /b> that the expression of exogenous TCR a and < /b> b genes could be detected in the transduced ... cassette aIb (P = 0. 014)< /b> , suggesting that the TCR transgene vector bIa yielded a better function of human antigen-specific TCR-redirected T < /b> cells than did vector aIb Cytotoxicity of TCR gene-transduced...

Ngày tải lên: 10/08/2014, 22:21

9 204 0
báo cáo khoa học: " Diffuse large B-cell non Hodgkin’s lymphoma in a 65-year-old woman presenting with hypopituitarism and recovering after chemotherapy: a case report" pptx

báo cáo khoa học: " Diffuse large B-cell non Hodgkin’s lymphoma in a 65-year-old woman presenting with hypopituitarism and recovering after chemotherapy: a case report" pptx

... as reflected by the PET scan imaging and < /b> no abnormal activity is now present in the pituitary Unusually, the pituitary was not enlarged on imaging and < /b> we speculate that the infiltration behaved ... pituitary’s large < /b> reserve capacity When symptomatic, posterior lobe involvement is Table Endocrine investigations before/after R-CHOP chemotherapy At presentation Four months after treatment Eight ... patient with diffuse < /b> large < /b> B- cell lymphoma metastasizing to the anterior pituitary, in whom pituitary function was restored after successful treatment of the lymphoma An early report of complete...

Ngày tải lên: 10/08/2014, 23:20

4 272 0
Báo cáo y học: "High nuclear expression of STAT3 is associated with unfavorable prognosis in diffuse large B-cell lymphoma" doc

Báo cáo y học: "High nuclear expression of STAT3 is associated with unfavorable prognosis in diffuse large B-cell lymphoma" doc

... Shaknovich R, Zhang Y, Cattoretti G, Ye BH: Constitutively activated STAT3 promotes cell proliferation and < /b> survival in the activated B- cell subtype of diffuse < /b> large < /b> B- cell lymphomas Blood 2008, 111(3):1515-23 ... for STAT3, anti-P-STAT3 antibody ( 9145< /b> , rabbit monoclonal antibody, Cell Signaling Technology) for P-STAT3Tyr705, and < /b> antibodies for BCL6, CD10, MUM1 (Santa Cruz Biotechnology) Subsequently, ... et al [15] also demonstrated that high STAT3 expression in ABC-DLBCL patients correlated with inferior overall survival, but not with GCB-DLBCL patients However, STAT3-high and < /b> STAT3-low subsets...

Ngày tải lên: 10/08/2014, 21:23

6 453 0
báo cáo khoa học: "Genomic profiling of plasmablastic lymphoma using array comparative genomic hybridization (aCGH): revealing significant overlapping genomic lesions with diffuse large B-cell lymphoma" ppt

báo cáo khoa học: "Genomic profiling of plasmablastic lymphoma using array comparative genomic hybridization (aCGH): revealing significant overlapping genomic lesions with diffuse large B-cell lymphoma" ppt

... Delecluse et al [1] They proposed that this constituted a new subtype of diffuse < /b> large < /b> B cell lymphoma (DLBCL); it was suggested as a distinct entity based on its blastic morphology, its clinical behavior ... Institute The use of these materials was approved by the Institutional Review Boards of participating institutions One H&E section of each case was reviewed to confirm that more than 80% of cells ... classified as a subtype of DLBCL at least at the genomic level However, it should be noted that most of PL cases studied not arise from oral cavities It would be of great interest to study more cases...

Ngày tải lên: 10/08/2014, 22:20

6 288 0
báo cáo khoa học: "Routine use of ancillary investigations in staging diffuse large B-cell lymphoma improves the International " ppsx

báo cáo khoa học: "Routine use of ancillary investigations in staging diffuse large B-cell lymphoma improves the International " ppsx

... can be seen that rIPI1 provides the best differentiation between the IPI categories and < /b> the largest point estimate hazard ratios To study the effect of treatment with Rituximab on survival, this ... Prednisolone and < /b> Bleomycin (MACOP -B) [15] Nine patients were treated with palliative intent with steroids alone or in combination with non-anthracycline based drugs Treatment details were not available ... (14.< /b> 9%) and < /b> (4.7%) and < /b> an IPI of and < /b> respectively The mean baseline IPI of the patient cohort was 2.41 with a standard deviation of 1.3 Treatment data showed that of 152 patients on whom data...

Ngày tải lên: 10/08/2014, 22:20

9 261 0
Báo cáo y học: "Clear cell variant of diffuse large B-cell lymphoma: a case report." docx

Báo cáo y học: "Clear cell variant of diffuse large B-cell lymphoma: a case report." docx

... Patients with GCBDLCBL had significantly better overall survival than those with ABC-DLBCL [18,< /b> 19] The patients with GCB-DLCBL had better prognosis than the non-GCB subtype Both ABC-DLBCL and < /b> ... immuno-phenotypic and < /b> cytogenetic morphological features that are intermediate between DLBCL and < /b> BL, and < /b> thus cannot be classified into either of these categories with certainty [25] The overlap between ... DLBCL [22] Commonly observed genetic abnormalities that likely contribute to pathogenesis include translocation of BCL6, BCL-2, c-Myc and < /b> FAS (CD95) mutations and < /b> aberrant somatic hyper-mutation...

Ngày tải lên: 11/08/2014, 00:23

6 449 0
báo cáo khoa học: "Management of stage one and two-E gastric large B-cell lymphoma: chemotherapy alone or surgery followed by chemotherapy?" potx

báo cáo khoa học: "Management of stage one and two-E gastric large B-cell lymphoma: chemotherapy alone or surgery followed by chemotherapy?" potx

... 0.551) between the two groups (figure and < /b> 2) Consent and < /b> statement of ethical approval Treatment-Related Toxicities As the treatment of each patient was decided by the medical staff of the centre, ... Cancer Centre in Rabat This study was approved by the institutional review boards of National Institute of Oncology, in Rabat Results Patients Characteristics Patients' characteristics are summarized ... competing interests Authors' contributions YS: Analysis and < /b> collected data, designed study and < /b> drafted the manuscript NI: participated in the design of the study, in the statistical analysis, and...

Ngày tải lên: 10/08/2014, 22:21

6 194 0
báo cáo khoa học: " Cardiac tamponade and paroxysmal third-degree atrioventricular block revealing a primary cardiac non-Hodgkin large B-cell lymphoma of the right ventricle: a case report" pptx

báo cáo khoa học: " Cardiac tamponade and paroxysmal third-degree atrioventricular block revealing a primary cardiac non-Hodgkin large B-cell lymphoma of the right ventricle: a case report" pptx

... intra-right ventricle obstruction Surgical resection of the mass was difficult and < /b> incomplete The tumor had infiltrated his right atrium, the atrioventricular septum and < /b> the proximal side of the right ... right ventricle Surgical removal was laborious but without complications The tumor was submitted to the pathology laboratory as white and < /b> red soft fragments measuring cm by cm by cm (Figures and < /b> 6) ... Chemotherapy remains the preferred initial treatment It should be guided by the immunohistological characteristics of the lymphoma and < /b> its extension to other Page of organs At the end of the treatment,...

Ngày tải lên: 10/08/2014, 23:20

5 298 0
The role of paxillin superfamily members  hic 5 and leupaxin in b cell antigen receptor signaling 1

The role of paxillin superfamily members hic 5 and leupaxin in b cell antigen receptor signaling 1

... factor B (NF- B) activity (Cantrell, 2002; Dal Porto et al., 2004) Brieftly, Akt was thought to play an important anti-apoptotic role by phosphorylating Bad, a pro-apoptotic protein (Datta et al., ... raft together with SFKs at resting state (Brdicka et al., 2000; Kawabuchi et al., 2000) BCR ligation will first activates CD45, a phosphatase that dephosphorylates the Cterminal inhibitory tyrosine ... FCγRIIB is a potent regulatory receptor that inhibits antigen-induced B cell activation Similar to CD22, it contains the ITIM motifs which can be phosphorylated by Lyn Phosphorylated FCγRIIB binds...

Ngày tải lên: 12/09/2015, 08:16

191 553 0
The role of paxillin superfamily members  hic 5 and leupaxin in b cell antigen receptor signaling 2

The role of paxillin superfamily members hic 5 and leupaxin in b cell antigen receptor signaling 2

... immunoprecipitation; IB, immunoblot stimulated via BCR The total cell lysates were subjected to immunoprecipitation with anti-FLAG antibody-agarose beads and < /b> immunoblotted with anti-phosphotyrosine antibody ... immunoblotted with anti-HA antibody to control for Lyn expression WT, wild-type It was possible that by generating the Y72F mutant, we had disrupted the interaction between LPXN and < /b> Lyn To test this ... various time points, and < /b> cells lysates were subjected to immunoprecipitation with anti-phosphotyrosine antibody and < /b> immunoblotted (IB) with anti-LPXN and < /b> anti-Lyn antibodies C, membrane recruitment...

Ngày tải lên: 12/09/2015, 08:16

11 334 0
Hóa 11 CB tiết 14

Hóa 11 CB tiết 14

... ch t < /b> hoá học T< /b> nh axit Axit nitric axit mạnh, dung dòch loãng phân li hoàn toàn thành ion H+ ion NO3 Dung dòch HNO3 làm đỏ quỳ t< /b> m; t< /b> c dụng với oxit bazơ; bazơ muối axit yếu t< /b> o muối nitrat Thí ... ph t < /b> Ho t < /b> động GV giới thiệu lọ đựng dung dòch HNO3 Yêu cầu HS quan s t < /b> nghiên cứu SGK để r t < /b> tính ch t < /b> v t < /b> lí HNO3: trạng thái, màu sắc, t< /b> nh tan nước… Ho t < /b> động HS: Trả lời theo SGK ph t < /b> Ho t < /b> ... HNO3 t< /b> nh ax t < /b> tính oxi hoá HS: HNO3 có t< /b> nh ch t < /b> chung axit: - Làm quỳ t< /b> m hoá đỏ - T< /b> c dụng với bazơ - T< /b> c dụng với oxit bazơ - T< /b> c dụng với muối axit yếu Ho t < /b> động GV biểu diễn thí nghiệm:...

Ngày tải lên: 08/07/2013, 01:25

4 345 1
TChon 14 PRESENT PERFECT WITH SINCE AND FOR.doc

TChon 14 PRESENT PERFECT WITH SINCE AND FOR.doc

... electricity light in the kitchen It was some thing quite unexpected: a house with electricity but without a kitchen light It was quite puzzling because our kitchen was a large < /b> room, perhaps the largest ... Yes, that’s fine h Oh, no I don t < /b> really like watching it Keys 12345678- V Give the correct form of the verbs in the blankets: My father (listen) ………………………………… to the radio last night Mr Tan (not ... September day It was not really a new house It was a hundred and < /b> four years old, but it was new to us The house had running water, gas and < /b> electricity but for some reasons, there was no electricity...

Ngày tải lên: 08/07/2013, 01:27

2 582 8
Giáo án  HH 9 (3 cột T17 - 18)

Giáo án HH 9 (3 cột T17 - 18)

... GV gọi hs cho ∆ thoả mãn yêu cầu toán * Ta t< /b> m số đo góc thông qua t< /b> m ? * B i t< /b> p 35 / SGK + HS + T< /b> m số đo góc thông qua t< /b> m t< /b> số lượng giác góc sử dụng máy t< /b> nh b t< /b> i đổi t< /b> t< /b> số lượng giác ... lại t< /b> p giải làm tiếp t< /b> p ôn chương lại SGK n t< /b> p chương I Trang Hình học - Vũ Đình Phương – THCS Thò trấn – NH : 06 - 07 Ti t < /b> 18 < /b> (tiếp theo) I.MỤC TIÊU :  Rèn luyện kỹ sử dụng máy t< /b> nh b t< /b> i ... cách hai thuyền A B ntn?  Hướng dẫn HS cách làm Vũ Đình Phương – THCS Thò trấn – NH : 06 - 07 Học sinh * B i t< /b> p 38 / SGK + T< /b> nh khoảng cách hai thuyền A B cách lấy đoạn thẳng IB trừ đoạn thẳng...

Ngày tải lên: 06/08/2013, 01:26

4 369 0
t 14

t 14

... thông tin liên lạc: - Máy bay siêu âm, t< /b> u hoả t< /b> c độ cao TTLL? - GV nêu thêm số thành t< /b> u: Ô t< /b> - Những phơng tiện thông tin liên lạc, ph t < /b> chạy lợng m t < /b> trời, t< /b> u hoả chạy t< /b> c sóng vô tuyến ... cho bi t < /b> thành t< /b> u công Máy t< /b> nh điện t< /b> , máy t< /b> động, hệ thống cụ sản xu t?< /b> máy t< /b> động - GV giới thiệu thêm T< /b> m nguồn lợng mới: ? Nguồn lợng đợc t< /b> o nh Năng lợng nguyên t< /b> , m t < /b> trời, gió, thuỷ ... tinh Đ t < /b> thành t< /b> u kì diệu lĩnh vực độ 300km/ h chinh phục vũ trụ: ? Em có nhận x t < /b> thành t< /b> u - 1957 phóng vệ tinh CMKHKT lần thứ hai? - 1961 bay vào vũ trụ ? Em lấy số ví dụ thành - 1969 đặt...

Ngày tải lên: 21/08/2013, 11:10

3 231 0
Unit 2 (period 14-18)

Unit 2 (period 14-18)

... to use the telephone in her family Listen to her talk and < /b> decide whether the statements are true (T)< /b> or false (F) Ask Ps to look at the pictures in the textbook and < /b> answer the questions Elicit ... Let students listen twice time - Write on board from to and < /b> call some students to come and < /b> write their answers - Let them listen on again and < /b> correct - Correct Task 2: Gap- fill T:< /b> Now listen to ... the context in the sentences - Check that Ss understand the word correctly - Call some students to give the answers - Ask others students to correct - Give the true answers Task - Ask students...

Ngày tải lên: 17/09/2013, 03:10

8 344 0
Phúc. T 14 - Luyện tập $ 8

Phúc. T 14 - Luyện tập $ 8

... thức chứng minh Ho t < /b> động 2: (20’) B i 62: R t < /b> gọn - Đưa thừa số dấu - HS thực theo hướng 33 k t < /b> hợp với vận dụng công 48 − 75 − +5 dẫn GV Hai HS lên a) 11 thức chia hai b c hai b ng, em khác làm ... vở, theo dõi nhận x t < /b> 16.3 − 25.3 − +5 = 11 - Nhân t< /b> mẫu làm b n b ng 4.3 3.3 5.2 = − 10 − + 17 =− = − 10 − + cho đưa thừa số dấu - Đưa thừa số dấu k t < /b> hợp với vận dụng công thức nhân hai b c ... 1,6 60 + 4,5 Củng Cố - Xen vào lúc làm t< /b> p, GV nhắc lại kiến thức cũ Dặn Dò: (5’) - Về nhà xem lại t< /b> p giải làm t< /b> p 62cd, 6 3b, 64 R t < /b> Kinh Nghiệm Ti t < /b> Dạy: …………………………………………………………………………………………………………...

Ngày tải lên: 26/09/2013, 20:10

2 283 0
GDCD 8 t 14 Lao Cai

GDCD 8 t 14 Lao Cai

... ông b Tuấn +Việc làm trai cụ Lam đợc,anh ta đứa b t < /b> hiếu Câu 3: +Chúng ta phải bi t < /b> kính trọng yêu thơng chăm sóc ông b cha mẹ -GV :Gia đình nôi nuôi dỡng ngời , môi trờng quan trọng học t< /b> p ... vệ ,t< /b> n trọng ý kiến con,không phân bi t < /b> đối xử -Ông b : trông nom,chăm sóc,giáo dục ,nuôi dỡng cháu c thành niên b t< /b> n2 ,nếu ngời nuôi dỡng V T< /b> ng k t-< /b> HDVN( 10) B i t< /b> p 1(sgk-33) B i t< /b> p 1(sgk-33) ... Hãy kể việc làm thể quan t< /b> m +Chăm sóc b mẹ b ốm thành viên gia đình em +Chăm sóc ốm đau sống hàng ngày? -GV gọi HS lên b ng làm , b sung -GV nhận x t < /b> Ch t < /b> kiến thức ti t < /b> (?) Thế gia đình ?Nêu...

Ngày tải lên: 09/10/2013, 20:11

3 326 1
lơp 4 t 14

lơp 4 t 14

... lớp Trường PTCS B i Thơm 1) KTBC: - GV: Gọi 3HS lên y/c làm BT ltập thêm - 3HS lên b ng làm b i, HS ti t < /b> trc, đồng thời ktra VBT HS lớp theo dõi, nx t < /b> làm - GV: Sửa b i, nx t < /b> & cho điểm HS b n ... lên sửa BT ltập thêm - 2HS lên b ng làm b i, HS GV: Phạm Tuy t < /b> Huyền Trang 23 Giáo án lớp Trường PTCS B i Thơm ti t < /b> trc, đồng thời ktra VBT HS lớp theo dõi, nx t < /b> làm - GV: Sửa b i, nx t < /b> & cho ... 2b, 3b Giáo viên giao việc HS làm Cả lớp làm t< /b> p HS trình b y k t < /b> làm HS trình b y k t < /b> tập B i 2b: l t < /b> ph t,< /b> đ t,< /b> nhấc, b t < /b> lên, HS ghi lời giải vào nhiều, b c tam cấp, l t,< /b> nhấc b ng, b c thềm...

Ngày tải lên: 18/10/2013, 12:11

43 275 0
giao an tin chuan tu tuan 14-18

giao an tin chuan tu tuan 14-18

... Mydocuments dụ thư mục My Documents Ho t < /b> động 3: Đổi t< /b> n t< /b> p tin, xoá t< /b> p tin G: T< /b> ơng t< /b> thư mục, em có  Đổi t< /b> n: thể đổi t< /b> n xoá t< /b> p tin Hãy nêu thao t< /b> c đổi − Nháy chu t < /b> vào t< /b> n t< /b> p t< /b> n thư mục? ... t< /b> ợng Gv: Ở ti t < /b> trước ta t< /b> m hiểu biểu t< /b> ợng hình Có loại biểu t< /b> ợng? Hs: Có loại: biểu t< /b> ợng biểu t< /b> ợng chương trình Gv: Chúng ta bi t < /b> cách chọn thực biểu t< /b> ợng trước Hãy nhắc lại cách thực hiện? ... n t < /b> Start xu t < /b>  Các thay đổi hình thức hiển thò b ng chọn Start, có dạng là: Start b ng chọn Start: menu (đầy đả) Classic Start menu (thu − Nhấn chu t < /b> phải Start ⇒ gọn) Gv hướng dẫn cách thay...

Ngày tải lên: 24/10/2013, 15:11

18 256 0
w