systematic reviews and meta analysis of diagnostic studies
Báo cáo y học: "Systematic review and meta-analysis of randomised trials and cohort studies of mycophenolate mofetil in lupus nephritis" pdf
... lupus nephritis from randomised trials and observational studies Materials and methods QUOROM (quality of reporting of meta- analyses) and MOOSE (meta- analysis of observational studies in epidemiology) ... maximum of five points were awarded to studies according to whether they were randomised, double-blind, and accounted for withdrawals or drop-outs and to whether the methods of randomisation and ... generally between and g daily The duration of follow-up of patients on MMF was generally between and 36 months, and average follow-ups were generally of year or longer None of the studies clearly...
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Báo cáo y học: " Effects of cyclophosphamide on pulmonary function in patients with scleroderma and interstitial lung disease: a systematic review and meta-analysis of randomized controlled trials and observational prospective cohort studies" ppt
... of reported standard errors of these studies We used a random-effects model assessing the weighted mean difference in the meta- analysis The overall pooled analysis included the mean changes of ... four our of six studies assessed the FVC at baseline and after 12 months of therapy, and five out of six studies assessed the DLCO at baseline and after 12 months In one study, one-half of the ... evaluation was limited by the small number of eligible studies and a lack of variability in quality across studies Results of the meta- analysis In the randomized clinical trials, the FVC mean difference...
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Tuberculosis in Liver Transplant Recipients: A Systematic Review and Meta-Analysis of Individual Patient Data doc
... tuberculosis skin testing and LTBI treatment, the prevalence and outcome of MTB infections, and the effects of patient factors and treatment on mortality from MTB infection PATIENTS AND METHODS plant ... (1/1945 to 12/ 2006), BIOSIS (1/1969 to 12/2006), and the Cochrane Database of Systematic Reviews and Central Register of Controlled Trials and manually searched retrieved bibliographies to identify ... rate of MTB reactivation,12 some transplant centers neither test for nor treat LTBI because of the perceived lack of efficacy and potential toxicity of drug therapy in liver transplant candidates.13-18...
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Báo cáo y học: "Estimated intelligence quotient in anorexia nervosa: a systematic review and meta-analysis of the literature" pot
... between 10 and 46 The mean IQ of the 14 studies ranged from 96.1 to 116.8 A meta- analysis using a random effects model revealed an estimate of the mean standardised mean difference (SMD) of 0.72 ... Table 2) Three of these studies used the NART and the revised NART (NART-R) and only one study used the WAIS The small number of studies did not allow a formal random effect meta- analysis However, ... USA) using the user-contributed commands for meta- analyses: ‘metan’ [19], ‘metainf’ [20], ‘metabias’ [21] and ‘metatrim’ [22] In order to estimate whether the IQ of those suffering from AN differs...
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Báo cáo y học: "Tolerability and adverse events in clinical trials of celecoxib in osteoarthritis and rheumatoid arthritis: systematic review and meta-analysis of information from company clinical trial report" potx
... trial), particularly discontinuation because of adverse events or lack of efficacy This systematic review and meta- analysis of celecoxib in osteoarthritis and rheumatoid arthritis was conducted using ... conditions Analysis of celecoxib dose, and of duration of studies, was restricted to discontinuations due to lack of efficacy or to adverse events, where there were more R649 than 20 events, and where ... intention-to-treat (number of patients randomised and receiving at least one dose of trial drug) analysis Homogeneity tests and funnel plots, though commonly used in meta- analysis, were not used...
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Báo cáo y học: " A systematic review and meta-analysis of neurological soft signs in relatives of people with schizophrenia" ppsx
... co-segregation (higher prevalence of the endophenotype in ill relatives of ill probands than in well relatives of ill probands); and (v) heritability (the extent of variation of the endophenotype that ... using Comprehensive MetaAnalysis version 2, a dedicated meta- analysis programme (BioStat, Inc, Englewood, NJ) The analysis was based on all included studies and consisted of three comparisons: ... as two separate studies Of the remaining six studies the country of origin of two studies was USA [24,25] and there was one study each from Sweden [27], Italy [14], Turkey [29] and France [26]...
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Báo cáo y học: "Efficacy of different types of aerobic exercise in fibromyalgia syndrome: a systematic review and meta-analysis of randomised controlled trials" potx
... MSt, MSc and AB participated in the collection of the data and analysis of the studies (see Materials and methods) AB and MSc participated in the study design and the interpretation of the data ... reliability determined the adequacy of randomisation, concealment of allocation, blinding of outcome assessors and adequacy Page of 14 of data analysis (was intention-to-treat -analysis performed?) (internal ... Page of 14 Table 1: Risk of bias (internal and external validity) of the randomised controlled trials' analysis Author, year Adequate randomisation Adequate allocation concealment Blinding of assessor...
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báo cáo hóa học:" Tooth loss and oral health-related quality of life: a systematic review and meta-analysis" potx
... these studies As far as we are aware of, this is the first systematic review and meta- analysis of the relationship between OHRQoL and tooth loss Data from our systematic review and meta- analyses of ... Summary of primary and additional outcomes of all included studies Additional file 2: Summary of data of all included studies and feasibility for meta- analysis 14 15 Author details Department of Oral ... Tooth loss and oral health-related quality of life: a systematic review and meta- analysis Health and Quality of Life Outcomes 2010 8:126 Submit your next manuscript to BioMed Central and take full...
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Báo cáo y học: "The effect of tight glycaemic control, during and after cardiac surgery, on patient mortality and morbidity: A systematic review and meta-analysis" pptx
... Haga et al.: The effect of tight glycaemic control, during and after cardiac surgery, on patient mortality and morbidity: A systematic review and meta- analysis Journal of Cardiothoracic Surgery ... biochemical markers of inflammation, and thus were not combinable with the other identified studies Two of the studies contained both diabetic and non-diabetic patients, with random allocation to ... Page of 10 Haga et al Journal of Cardiothoracic Surgery 2011, 6:3 http://www.cardiothoracicsurgery.org/content/6/1/3 Page of 10 Figure Results of the meta- analysis performed on the incidence of...
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Báo cáo y học: "Diagnostic imaging for chronic plantar heel pain: a systematic review and meta-analysis" ppsx
... Figure Forest plot of studies reporting the thickness of the proximal plantar fascia by MRI Forest plot of studies reporting the thickness of the proximal plantar fascia by MRI of 47% and did not apply ... objective of this systematic review was to investigate the diagnostic imaging features associated with CPHP and evaluate study findings by meta- analysis where appropriate The majority of studies ... assessor and had a quality index score of 43% A description of the methodological variability between studies is available in Additional file As the protocols and participant Figure Forest plot of studies...
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Báo cáo y học: "Effect of children’s shoes on gait: a systematic review and meta-analysis" potx
... 11 of 13 shoes [8,23] Unfortunately, meta- analysis of kinematic variables was restricted by inconsistencies in biomechanical models and under-reporting of standard deviations/ error Meta- analysis ... did not standardise the shoe worn [7,9,10,25,26] Description and methodological approach of included studies The description and nature of the included studies are shown in Table Nine studies investigated ... comprised the average of angle of gait relative to ipsilateral line of progression and angle of gait relative to the direction of gait The variable length comprised the average of stride and step length...
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báo cáo khoa học: " Efficacy of pharmacotherapies for short-term smoking abstinance: A systematic review and meta-analysis" pptx
... patients are at increased risk of complications or repeat Figure effects meta- analysis of varenicline versus placebo at weeks post-TQD Random6 Random effects meta- analysis of varenicline versus placebo ... with “nicotine” AND “smoking” AND “gum OR Patch OR spray OR inhalers OR Tablet OR lozenge” AND “random*” 280 abstacts were obtained when using “bupropion” and “smoking” and “random” and “clinical ... smoking reduction studies 4: smoking abstinence and craving studies 12: not NRT side effect and abstinence related studies 1: genotype and NRT response 115 NRT studies included in analysis 101 in...
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Báo cáo y học: " Parental and household smoking and the increased risk of bronchitis, bronchiolitis and other lower respiratory infections in infancy: systematic review and meta-analysis" ppsx
... review 29 studies included in updated meta- analysis 31 studies included from Strachan and Cook Review 60 studies included in updated meta- analysis Figure Flow diagram of included and excluded studies ... Prevention and Health Promotion, Office on Smoking and Health 2006 Department of Health Department of Health and Social Services Northern Ireland, The Scottish Office Department of Health and Welsh Office: ... socioeconomic status, and maternal education Page of 11 Methodological quality of studies and publication bias The methodological quality of the 60 studies included in the meta- analysis, as judged...
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Báo cáo y học: " Female smokers beyond the perimenopausal period are at increased risk of chronic obstructive pulmonary disease: a systematic review and meta-analysis" ppsx
... currently the 4th-leading cause of mortality and the 12th-leading cause of disability, by the year 2020 it will be the 3rd-leading cause of death and the 5thleading cause of disability worldwide [3,4] ... The abstracts of these articles were selected and reviewed Of these, 67 articles were retrieved for a detailed review After excluding studies that used identical cohorts (n = 41) and studies that ... to analysis of the relationship between age and gender-related differences in the annual decline in FEV1% pred Unweighted smoking status Unweighted analysis of the relationship between age and...
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Báo cáo y học: "Efficacy and safety of non-invasive ventilation in the treatment of acute cardiogenic pulmonary edema – a systematic review and meta-analysis" docx
... critical analysis of the safety of NPPV and CPAP in the treatment of ACPE A very recent meta- analysis unfortunately addressed only some of the questions to which clinicians need answers Masip and ... pressure support ventilation Materials and methods Study design A systematic review and meta- analysis of RCTs focusing on the effect of CPAP and NPPV in the treatment of ACPE was undertaken The methodological ... initiation and direction of the review LFA is responsible for study design, methods and statistical analysis JCW and LFA selected studies and extracted data JCW, LFA and AC-P interpreted results and...
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Báo cáo y học: "Utility and safety of draining pleural effusions in mechanically ventilated patients: a systematic review and meta-analysis" pps
... TA: Meta- Analyst: software for meta- analysis of binary, continuous and diagnostic data BMC Med Res Methodol 2009, 9:80 21 The Newcastle-Ottawa Scale (NOS) for assessing the quality of nonrandomised ... difficult), and risk Goligher et al Critical Care 2011, 15:R46 http://ccforum.com/content/15/1/R46 Page 11 of 14 Figure Forest plot of meta- analysis of studies reporting the rate of hemothorax ... Moher D, Becker BJ, Sipe TA, Thacker SB: Meta- analysis of observational studies in epidemiology: a proposal for reporting Meta- analysis Of Observational Studies in Epidemiology (MOOSE) group JAMA...
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Báo cáo y học: "Endothelial A comparison of early versus late initiation of renal replacement therapy in critically ill patients with acute kidney injury: a systematic review and meta-analysis" pdf
... meta- analysis of 15 unique studies compared “early” versus “late” initiation of RRT Figure Funnel plot of all 15 studies X-axis is log of risk ratio of death Y-axis is Standard error of Log Risk ratio of ... Summary of the completed checklist of quality measures for reporting of systematic reviews and meta- analyses Additional File 2: Summary of search strategy Detailed summary of search terms and strategy ... cohort and/ or randomised/quasi-randomised clinical trial (RCT) design; 2) adult critically ill population; 3) diagnosis of AKI; 4) description of factors related to timing of initiation of RRT; and...
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Frailty as a predictor of future falls among community dwelling older people a systematic review and meta analysis
... log-transformed upper and lower limits of 95% CI by 3.92 These data of each study were entered into the Review Manager and Comprehensive Meta- Analysis to perform meta- analysis and meta- regression analysis ... Longitudinal Study of Meta- analysis of studies presenting OR ORs from studies, including a total of 60,577 individuals, were combined to calculate a pooled OR and 95% CI using a random-effects model ... Each of the included studies was assessed using this scale and considered to have adequate quality to be included for meta- analysis if it met or more items out of Statistical Analysis OR, RR, and...
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Single and dual task tests of gait speed are equivalent in the prediction of falls in older people a systematic review and meta analysis
... Equivalence of single and dual task gait speed in the prediction of falls M This systematic review and meta- analysis of 31 studies revealed that slower gait speeds under both single and dual task ... Assessment of Diagnostic Accuracy in Systematic Reviews (QUADAS) tool was also used to provide a general standardised rating of methodological quality (Whiting et al., 2003) Page of 52 2.4 Selection of ... when standing and walking, which are required in many real-life situations 4.3 Strengths and limitations of the analysis This is the first meta- analysis focusing on the predictive ability of walking...
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